Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75611	Gw-5074	GSE92742	MCF10A	Human	6h	2uM	EID0435

Response Information :

Types	Number	Response transcription factors
Up-regulation	110	IKZF1; EGR3; ELF1; PSMD9; SMARCE1; KDM2A; TCFL5; HOXA1; RNF4; EED; EGR4; DDIT3; UBE2B; BATF; WHSC1; CEBPA; CRK; ING3; NCOA6; TOB1; ZNF226; RUVBL2; RUNX3; SFPQ; ATF1; PATZ1; YBX2; NR1D2; POU2F2; VEZF1; NFAT5; ARID4A; PRRX2; DLX2; POU5F1B; SMAD5; SMAD2; NAB1; BHLHE40; TSC22D4; HLTF; ZBTB25; TAF1D; MED7; CARM1; ELK1; RBL2; TSC22D1; KLF9; DNAJC1; TEAD1; IRF4; TGIF1; RNF6; ZNF23; ZFP64; MTF2; PMS1; BTAF1; PLAGL2; MAFG; SMAD3; STAT5A; PURA; MYB; BIRC2; NUP62; DNMT3B; ARNTL; MTA1; HMGB3; HDAC1; BRD8; C1D; BRCA1; STAT3; RUNX1; SCAND1; TAF10; POLR2A; RBBP7; PLAG1; MAGED1; KAT6B; LPIN2; CBX6; PIR; STAT6; FOXO1; HMGN3; SMAD1; BBX; PHF20; KDM5D; PTTG1; PDLIM1; SATB2; CREB3L1; SMARCA2; SREBF1; HMGA1; SAP30; HOXC10; TWIST1; TLE1; BHLHE41; LMCD1; HOXC6; ERBB2; BASP1
Down-regulation	91	TRIB3; ARNT2; TCEA2; TRIM29; IRF6; APEX1; TEAD4; ZNF117; TP63; JUP; TAF7; ZNF512B; ZNF551; ZFP69B; MEIS2; ZNF12; NFE2L3; TRIM16; GTF2I; ZHX2; GMNN; GTF2IRD1; ZNF586; CDK2; TRIM22; ZNF43; PITX1; SOX11; FOXN3; TFEC; ZEB1; ZNF274; CAMTA1; EYA1; ERBB4; PSMC3; MYT1; AES; MYBL1; ZNF219; FOXK2; GRHL2; ZKSCAN1; EN1; MYCL; IKBKAP; CREBL2; ZNF711; TBL1XR1; CUX1; ZNF268; MED24; ACTL6A; ARNTL2; SMAD4; IFI16; INSM1; SSBP3; TRPS1; IRF9; MNDA; NHLH2; GATA6; FLI1; ZNF532; CHD9; NR2F1; EHF; ZNF107; NR2F2; TCF7L1; HBP1; NPM1; NFKB2; ZNF467; ZFP36L2; TFAP2C; TCF21; CREB3L2; CUX2; ZNF91; DAXX; WT1; BTG1; PCGF2; FOXF1; TBX3; ZFPM2; ARID5B; ISL1; TOX3