Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75541	Torin-2	GSE92742	MCF10A	Human	6h	0.08uM	EID0434

Response Information :

Types	Number	Response transcription factors
Up-regulation	162	MYBL2; RELB; HOXC6; TSC22D4; TAF10; ATF3; TSC22D3; RNF141; CRK; CEBPD; POU3F1; FOXD1; NFKBIA; FOXJ3; EHMT1; YY1; EGR1; FOXO4; ARNTL; ASXL1; CAPN15; YBX1; HOXA1; HOXC4; TCF15; GABPA; POU2F2; USP22; KDM2A; ARID3B; NR1H3; ZNF646; ZNF205; TADA2A; PRKDC; SMAD3; DYRK1B; CTR9; BLM; CXXC1; KLF6; BRD8; PPARD; FLNA; NFIB; SOX4; SMARCB1; HMGA1; ZBTB14; MNAT1; SPIB; TAF9B; CCNC; SLC2A4RG; GFI1; IRF5; RUNX3; NRBF2; NR3C1; NCOR2; TGFB1; HR; HOXB7; TMF1; FOXC1; KDM4A; TCEA1; BCL3; CBX3; NFYB; MEF2A; BLZF1; RNF14; PROX1; BTG1; KLF5; CBFB; WHSC1; RB1; TBPL1; GTF2I; PBRM1; CNOT3; MSX1; TRIM28; NPAT; EGR2; KLF7; MXD4; KDM5C; VPS72; TP53; SKI; NUP62; BRPF1; KMT2B; NFE2L1; PDLIM1; MAZ; MNT; MED15; NKX2-2; MLXIPL; LOXL2; APBB1; CSDE1; BRD3; ELF3; CBX6; HIPK3; NR0B1; SMARCE1; MAFG; ZNF226; HLTF; ID4; PAX5; ELF1; TERF2; EPAS1; TWIST1; EP300; ING3; HTATIP2; RBL2; VEZF1; RBBP8; AATF; RBPMS; DDIT3; PA2G4; LMCD1; SMARCC1; MED1; IRF8; POU4F1; BMI1; CREBZF; SMAD2; FOSB; BHLHE40; MTA1; ZBTB20; BCL11B; MAFB; CHD7; SOX9; ELK3; KLF2; JUND; SSRP1; LITAF; EGR3; ID3; TOB1; PURA; ATF4; CALR; BHLHE41; ZBTB18; NR2F6; RUVBL1
Down-regulation	191	TCEA2; IKBKAP; MNDA; ARNT2; GMNN; CRYM; TRIB3; HIVEP1; ABT1; TAF11; ZNF467; DNMT1; JUN; ZNF12; ZNF184; FOXA1; ZNF274; ELF2; MEIS2; SIX2; CCDC59; ZNF124; ZNF22; SMARCD3; ZNF586; TRPS1; ZNF512B; ARID5B; KLF1; NFE2L3; ZNF239; TAL1; TBL1X; CCNE1; HLF; RBFOX2; SAFB2; ZSCAN9; ZNF215; ZNF76; PIAS4; BCL11A; RREB1; FOXF2; AFF2; PBX2; TCF21; ZNF423; TAF1A; DEK; FOXN3; NFE2; PQBP1; PKNOX2; AR; ADNP2; CD3D; HOXA10; DNAJC2; JAK2; ILF2; ZNF84; PRDM2; ZEB1; ZNF174; TOPORS; ZNF667; ZFPM2; CBX7; ZNF107; PHIP; MGA; PFDN5; THAP4; CCNH; ZNF268; TDP2; WWC1; FLI1; MYBL1; ERCC3; ZNF140; TRIM27; NEUROD1; CDC5L; PHF2; PHF1; KAT8; BCL6; BNC2; ZNF232; POLR3C; TFAM; ZBTB11; RING1; GLI3; IRF6; ZNF544; GABPB1; CITED1; ZNF263; UBE3A; SP3; ZNF136; HDAC4; MYB; ZNF415; NCOR1; ZBED2; ZNF337; COPS2; HIPK1; TEAD4; EHF; PSMD9; ZNF112; ZNF43; MED17; RNF138; FOXE1; CDK2; KAT2B; E2F8; ZNF148; EHMT2; NFE2L2; HOXA11; IRF9; ISL1; RXRA; CERS6; ZNF180; SP140L; ZNF593; RSF1; ERBB4; STAT4; NR1H4; ZFP36L2; NKX3-1; FOSL2; SP100; RERE; PRDM1; ZNF329; DAXX; ETS1; MDM2; RFXANK; OSR2; SOX18; WT1; TFEC; CUX2; MYCL; HHEX; FOXF1; SMARCA4; RYBP; TAF9; SMARCA1; SIX3; ZNF14; ESR1; GRHL2; REPIN1; TGFB1I1; ZNF32; SUB1; AES; EYA1; TXNIP; NFAT5; BACH2; SNAI2; ZNF331; ETV5; PEG3; ZNF652; CREB3L2; INSM1; HIC2; HIRA; SALL1; SAP30; PBX3; CREM; NFKB2; MECOM; ZFP36L1; E2F2