Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75540	Torin-2	GSE92742	MCF10A	Human	6h	0.4uM	EID0434

Response Information :

Types	Number	Response transcription factors
Up-regulation	188	IKZF1; RELB; TSC22D3; CEBPD; KLF6; TAF10; HOXC6; SCAND1; KLF5; NFKBIA; CRK; ARNTL; FOXO4; TSC22D4; FOXD1; MYBL2; HDAC6; HMGA1; USP22; ASXL1; MAZ; KLF9; ERBB2; MXD4; BRD8; STAT3; TXNIP; KDM5A; ELF1; DNAJC1; YY1; KLF7; USF2; CBX3; ARID4A; TSG101; YBX2; ELK1; KLF13; RNF141; RBL2; SMAD3; SKI; POU3F1; AFF4; NRL; FOXC1; SPIB; PPARD; DDIT3; RFX7; SMARCB1; PMF1; STAT5A; ASH1L; HIVEP2; TAF1; MEF2A; MNAT1; SETD3; ZBTB25; RUNX1; MNT; NFAT5; KDM2A; TCFL5; NR1H3; NCOR2; PPP1R13L; TCF15; MKL1; YBX1; STAT5B; SIM2; BATF; MMS19; ING3; TOB1; HOXC4; CARHSP1; EGR1; KLF2; TGFB1; IRF5; ERCC2; ETV6; CHD3; TRIM28; BBX; ING1; NFE2L1; MYT1L; BLM; RB1; DLX2; ZFP64; NUP62; BRPF1; MLXIPL; NR3C1; IRX5; MXD1; PPARGC1A; BRD3; MED15; NFIB; LITAF; NR1D2; ZHX3; NCOA6; ZMIZ2; BCL11B; BCL3; LMCD1; FEV; SAP30; SLC2A4RG; POU2F2; KMT2B; PHOX2B; TGIF1; NRBF2; MAFF; MTA1; KDM5C; PNRC1; GTF3A; MED1; CAPN15; BMI1; PDLIM1; SNAI1; NCOA3; UBE2B; HDAC5; NR2E1; AFF1; ATF4; SIRT2; PIAS2; STAT6; TDRD3; BTAF1; RBBP4; ELF3; AATF; HLTF; HOXA1; CBFB; MSX1; MLXIP; BRD2; PA2G4; EPAS1; FLNA; PURA; JUNB; MBD2; TP53; BANP; CNOT3; IRF7; SOX4; XBP1; BRCA1; NFATC1; BTG1; FOSB; PSMD9; BHLHE40; TSC22D1; BAZ2A; ZEB2; ID3; EDF1; ZNF217; MYRF; ZNF281; ZNF165; VPS72; JUND; FOXO1; CITED2; ZBTB38; CALR; ZIC1; HTATIP2; ELK3
Down-regulation	204	GMNN; ARNT2; TCEA2; IKBKAP; ZNF586; DNMT1; PHIP; ZNF12; TRIB3; RBFOX2; TAF1A; ZNF623; ZSCAN9; PIAS4; SOX13; CRYM; MEIS2; JUN; FOXF2; ZNF274; ZNF557; ZNF551; GTF2A2; ZNF180; ZNF248; PITX2; MED21; NFE2L3; MYBL1; ZNF544; ZBED2; HIVEP1; ARID5B; MGA; RRN3; ZNF682; ZNF512B; ZNF146; TCF21; XRCC6; ZNF141; POU2F3; CUX2; ZNF492; FOXF1; ZNF467; ZFPM2; TDP2; KAT2B; ZNF239; ZNF112; ZNF235; TGFB1I1; WT1; MNDA; SOX2; ZNF334; TAF11; CHD9; ABT1; HOXB5; ZNF304; AR; AFF2; ZNF215; UBE3A; ZEB1; THAP10; SSX1; KLF1; ZNF667; CERS6; CTCF; ZNF74; ZFP69B; TEAD3; MYBBP1A; ZNF273; STAT1; ZNF135; NEUROD1; SOX17; HLF; ZNF43; RNF138; PLAGL1; ZNF136; HOXD1; SOX18; ZNF227; WDR77; ZNF124; NFE2L2; PKNOX2; CCNC; BNC2; MED17; TOX3; CBX7; CDK2; RREB1; ZNF268; CBFA2T3; ESR1; ZNF571; RSF1; BASP1; ZNF711; SRY; ZKSCAN4; ZNF331; ZNF257; ZNF107; E2F8; PARP1; HEY2; TEAD4; DACH1; CD3D; DLX5; MAF; SUPT4H1; FOXA1; TOPORS; DDX17; TBX3; NANOG; ZBED4; WWP1; SOX11; TRPS1; SRF; ID4; AHR; ZNF350; IRF6; ZNF140; SALL2; SMARCD3; ZNF593; TAL1; ZNF75D; IRF9; HOXB2; HIPK1; ZNF611; DAXX; ZNF329; REL; EYA1; ZNF675; SALL1; FOXE1; POU2AF1; ZNF232; RXRG; TFCP2; TFAP2C; TFEC; HMGXB4; ZFHX3; SHOX2; NR1H4; OSR2; L3MBTL1; PFDN5; PIR; ACTL6A; CBX5; TLE2; ATN1; NR5A2; CCNH; EHF; BCL11A; SATB2; ZNF264; ZNF468; ZFP36L1; NR0B1; NKX3-1; TP63; SP140L; ZBTB20; HOXB13; MED13; MEIS1; CREM; MYCL; SMAD6; ZNF652; HIC2; NR4A2; VDR; HHEX; RBPJ; TOX; IFI16; IRF8; BHLHE41; LEF1; NR2F1; SMARCA1; NFKB2