Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75538	Torin-2	GSE92742	MCF10A	Human	6h	10uM	EID0434

Response Information :

Types	Number	Response transcription factors
Up-regulation	103	ZNF586; PPARD; TSC22D3; NFX1; KLF6; CEBPD; RELB; HOXC6; FUBP1; HMGA1; ARID4B; DNAJC1; ARID3B; FOXJ3; BTAF1; PMF1; ARNTL; FOXO4; POU5F1B; ATF4; BTG1; BRD8; NFKBIA; SOX4; HBP1; UIMC1; GATA2; TBX19; KLF7; EZH1; ZMIZ2; CARM1; LITAF; DDIT3; HOXC4; TXNIP; ASXL1; MMS19; NR3C1; BLM; KMT2B; PSPC1; TCEA1; PHOX2B; TGFB1; NCOA4; CNOT3; RBBP4; SOX10; RNF141; SLC2A4RG; ASCL1; RNF10; KLF5; TRIM28; IL16; BRPF1; SPIB; RBM39; DMTF1; LMCD1; MAZ; TRIP6; TP53; KDM5B; MLXIP; FOXD1; MLLT10; ZNF83; HTATIP2; JUP; RBPMS; FLNA; NFIB; FOSB; FOXC1; MED15; TAF10; CNBP; ELF1; PLAG1; NCOR2; PCGF2; RCOR3; RBL2; XBP1; JUND; TLE4; VPS72; ELF3; GTF3A; SMAD3; BHLHE40; ZBTB18; ZNF217; SMARCC1; HOXC10; PSMD9; ZSCAN18; TCERG1; CREB3L1; MAFB; BHLHE41
Down-regulation	112	IKBKAP; ADRB2; HMGA2; FOSL1; ZNF12; MYC; DACH1; FOXF2; HES1; ZNF557; PLAGL2; ZNF22; TFAM; MNDA; HOXA10; TAF1A; WT1; RNF6; HDAC4; ID1; SIX1; TGFB1I1; FOXA1; MED17; ZNF423; BASP1; ARID5B; ZNF184; ERBB4; CLOCK; SSX1; TOPORS; ZNF180; ZNF136; SIAH2; RRN3; SMARCD3; ZNF148; ZNF107; ZNF124; ZNF571; ITGB3BP; NFE2; NR4A2; CUX2; REST; CD3D; MED21; HLF; HHEX; SOX17; MEIS2; MEOX1; ZBTB38; ZNF112; NR5A2; CEBPZ; HOXD1; ZEB1; NEUROD1; ZNF44; ZBED2; CBX7; TCF21; TRIM32; SMAD1; ETV5; KLF10; RREB1; AR; ZNF43; JUN; NFE2L3; BARX1; FOXF1; MYB; ESR1; PEG3; ZFPM2; NR4A1; TEAD4; ZNF14; SATB2; TAL1; DAXX; POU2AF1; SHOX2; NR3C2; CREB5; L3MBTL1; RBBP8; TOX3; LEF1; MECOM; KLF4; URI1; MEIS1; E2F5; KLF11; SMARCA4; SMARCA1; NKX3-1; TOX; EGR3; HOXB2; MDM2; KAT2B; BCL11A; NFKB2; ZFP36L1; SNAI2; E2F2