Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75537	Torin-1	GSE92742	MCF10A	Human	6h	0.08uM	EID0434

Response Information :

Types	Number	Response transcription factors
Up-regulation	127	CEBPD; NFKBIA; RUVBL2; TGFB1; ENO1; SPIB; TAF10; PPARD; NCOR2; TSC22D3; DNAJC1; HMGA1; FOXO4; TRIM28; CRK; PMF1; ASXL1; RELB; ZNF205; DDX54; TSC22D4; AFF4; PBXIP1; NFIB; ATF7IP; POU2F2; KLF6; SMAD5; USF2; HES1; KMT5A; CNOT3; HCFC2; BRD8; MYBL2; ZBTB32; IRF3; SREBF1; TCEA1; ERCC2; SMAD3; KDM5B; HOXA5; SIRT2; ELK1; FOSL1; KLF13; RUNX1; IL16; PPP1R13L; CAPN15; MXD4; TRIP6; KMT2B; EGR1; SOX4; TSC22D1; STAT3; TRRAP; NFAT5; NR1H3; MLXIPL; PA2G4; BTAF1; SUPT5H; FOXD1; KLF7; TXNIP; CALR; PPARGC1A; RBPMS; VPS72; RNF141; BCL3; SND1; FLNA; SKI; DBP; CITED1; RUNX3; HOXA1; TMF1; KAT2A; ELF3; ARNTL; MTA1; HEY1; NR3C1; MEF2A; BTG1; MAGED1; STAT6; RBL2; MNT; KLF9; MKL2; CBX6; ZNF580; BAZ2A; ID3; GTF2I; MED1; EPAS1; SOX9; BATF; CAMTA2; NR1D2; ELK3; LITAF; ZBTB18; FOXC1; KLF2; PCGF2; NKX2-1; YBX3; HTATIP2; FOXG1; HOXC6; PSMD9; TFCP2L1; CREB3L2; MED24; RHOA; PURA; PDLIM1; SMARCA2; SMARCD2
Down-regulation	139	HMG20B; TBL1X; MNDA; ZNF423; PHIP; DACH1; ZNF12; TDP2; ZNF248; TAF1A; HDAC4; UBE3A; ZNF184; IKBKAP; ZNF74; MTF2; ZNF467; ZNF443; ZNF239; JUN; ZNF623; RRN3; TRIB3; ZHX2; TAF11; ITGB3BP; ARID5B; MYBL1; FOXF2; ZKSCAN7; RREB1; ZSCAN32; E2F8; ARNT2; BCOR; NFE2L3; WT1; PATZ1; HMGB1; SUMO1; ERBB4; KLF1; PITX2; ZNF770; FOXF1; ZNF124; THAP10; HIPK1; SOX17; RNF138; EZH2; CERS6; MYB; NFE2L2; ZSCAN16; TAL1; CRYM; IRF1; TCF21; MEIS2; NFYC; BCL11A; ZNF250; SHOX2; CTCF; ZNF3; TEAD3; CNOT6; GTF2IRD1; SIAH2; RAD21; HDAC2; TRIM32; ZEB2; SOX11; ENY2; ZNF263; ZFPM2; ZBTB1; AEBP1; MED21; CBFA2T3; DAXX; LEF1; THAP4; JAK2; REPIN1; TEAD4; CD3D; ZNF43; TGFB1I1; ZNF93; HOXD3; CHD7; PIR; THAP7; HIC2; WWP1; ZNF711; IRF9; CAMTA1; AR; ZNF611; SALL1; ESR1; ZNF232; SMARCD3; ZNF160; NR2F6; NANOG; ZEB1; TBL1XR1; ZNF329; SATB2; CEBPZ; HOXB2; ZZZ3; BNC2; SMAD6; SP140L; URI1; CREM; TOX3; ZSCAN31; KLF11; KLF10; HOXD1; STAT4; HOXC10; HIRA; NFKB2; GRHL2; POU4F1; ZIC1; ZBTB20; ZFP36L1; NKX3-1; TBX3; E2F2