Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75536	Torin-1	GSE92742	MCF10A	Human	6h	0.4uM	EID0434

Response Information :

Types	Number	Response transcription factors
Up-regulation	107	TCFL5; ETV1; SPIB; SP110; EED; NFIX; RBBP7; TSC22D3; RUNX3; RORA; CARM1; SP140; GATA4; YY1; TSG101; TRAK1; KLF6; JUP; MNT; EHF; ELF5; PAX5; KLF5; CITED1; MED4; SLC2A4RG; FUBP1; TP63; NFKBIA; RNF14; PRKDC; ASXL1; HOXC6; HAND1; HMGA1; FLNA; ARNTL; RUVBL2; ELF1; EYA2; PPARGC1A; CARHSP1; TEAD1; RNF141; MBD2; ATF7IP; TAF9B; DNAJC1; TRIM28; ID1; FOXO4; E2F2; FOXD1; RBL2; ZNF580; SMAD3; HOXB6; PHOX2A; NCOR2; TCF7L1; XBP1; STAT6; JUND; PROX1; PFDN5; MTA1; TAF10; KLF9; IRF4; MKL2; HEY1; PA2G4; TBPL1; NKX2-2; CNOT3; MSX1; ID3; FOXG1; NFIB; RBBP8; BCL3; BTG1; HDAC1; TFCP2L1; VPS72; PDLIM1; TGFB1; ASCL1; BRCA1; NFE2L1; SOX9; INSM1; VEZF1; ZNF281; SMARCC1; MYRF; BRD4; HOXC10; EPAS1; PSMD9; CALR; ELK3; MAFB; HTATIP2; ID2; SNAI2; CDK7
Down-regulation	123	MNDA; ZNF248; DACH1; SMARCD3; STAT1; ZNF12; TAF1A; GTF2IRD1; IRF1; SOX2; ZNF652; HSBP1; CD3D; PIAS1; UBE3A; REPIN1; ZNF329; TRIM22; RRN3; ZNF394; SP3; ZNF467; MAK; E2F3; TRIM24; COPS2; BNC2; MGA; SUPT4H1; ZNF423; THRA; ZSCAN9; ZBTB43; RNF138; AHR; HNRNPD; RLF; RHOA; HMGB3; LEF1; HLX; TCF7L2; CTCF; AR; SOX11; CHD1; NR4A1; BAZ2B; SIX1; ILF2; SFMBT1; NR4A2; CUX2; ZNF43; HDAC2; ZNF468; CERS6; PEX14; ZNF175; BRD3; ZNF304; ZNF45; ZNF331; ZNF93; ZNF529; TEAD3; ZNF189; PREB; RYBP; ZNF573; CTBP1; TAL1; KAT7; ZSCAN31; MLXIP; ZNF263; ZEB1; RREB1; FOSL2; NRIP1; TCF12; WT1; BACH1; TSC22D2; DAXX; OSR2; CREB3L2; AEBP1; SHOX2; FOSB; HOXB2; ZNF136; PLAG1; ZNF721; CBFA2T3; LMCD1; ING3; KLF4; ST18; MYB; TRIP6; CEBPZ; NFKB2; DNMT3B; TCF7; TEAD4; TFEC; AFF1; ATF3; PBX3; ZNF264; HOXD1; TBX3; ZEB2; ZFPM2; TOX; IRF9; MEIS1; TCERG1; SATB1; MEIS2; ZNF91; NKX3-1