Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75533	Fostamatinib	GSE92742	MCF10A	Human	6h	0.08uM	EID0434

Response Information :

Types	Number	Response transcription factors
Up-regulation	121	GABPA; SREBF1; HMGA1; FOXD1; RFX7; NCOA4; FOXC1; AFF4; CRK; SMARCB1; TRIM28; BLM; HOXA5; NFKBIA; YY1; PATZ1; TRIM29; KDM2A; FOSL1; MED4; HOXA1; HOXC6; PIAS2; SIM2; ELK1; BRD8; ASXL1; MYBL2; YAF2; RNF14; RBBP4; POLR2A; DNAJC1; NPAS2; SAP18; MNAT1; NFIB; TAF9B; HIVEP2; HTATIP2; CTR9; EGR3; NKX2-2; TSC22D4; NRBF2; SMARCA2; XBP1; HIPK3; RUNX1; PPARGC1A; PRKDC; EP400; RUVBL2; WHSC1; RNF10; TRIM25; SOX4; TCEA1; E2F2; AIP; NCOR2; RNF4; KMT2A; RNF141; MNT; BHLHE40; ZHX3; CEBPG; TBPL1; MAGED1; EGR1; CBX3; CREB3L1; NR0B1; ZNF23; FOSB; MAFF; COPS5; BMI1; EYA2; TP53; KLF5; PA2G4; SMAD1; DDIT3; HDAC1; POU4F1; BCL11B; TFDP1; ZNF226; BACH2; RBL2; ELF1; ST18; MED1; SMAD3; CNOT1; JUP; IRX5; SMAD2; TGFB1; ARNTL2; GABPB1; MEF2A; DPF2; PDLIM1; FLNA; PITX1; RHOA; SMARCC1; NR2F2; PSMD9; PUF60; YBX3; NKX3-1; MED24; ZNF165; RUVBL1; CALR; SNAI2; PARP1
Down-regulation	141	ZNF12; ZNF124; MNDA; ARID5B; ZNF44; ARNT2; ERBB4; ZNF665; PHIP; CHD9; ZNF544; CBX7; ZNF623; PBX2; ZNF423; ZNF611; BNC2; ZNF415; ZNF721; NFE2L3; ZNF117; CREB3L2; REPIN1; ZNF91; ZSCAN9; ZNF444; IRF7; ZNF512B; SMARCD3; SCAI; DACH1; ZNF652; ZNF264; RLF; ZFPM2; PIAS1; HLF; WNT4; RBFOX2; CRYM; BCL6; JUN; TCF4; ZNF160; TRIM24; IRF9; ZNF562; SOX17; SP3; NFATC4; ESR1; PAWR; ZEB1; ESRRG; ZNF606; ZNF467; PRDM2; HDAC4; IRF6; ITGB3BP; TRIM22; RREB1; CERS6; ZNF136; ZNF551; UBE3A; TDP2; ZNF304; ZNF93; ZNF43; ZNF350; IRF1; SALL1; BBX; RXRG; AHR; TCF7L2; ID4; NFE2L2; PEX14; NFKB2; AES; KLF13; AR; ZNF14; DAXX; HIRA; HOXD1; HMGB2; BCL11A; TEAD3; NR1H4; ISL1; ZNF180; SALL2; MEIS2; RERE; SIX3; PCGF1; CD3D; TCF7; CREB1; CTNNB1; RBM39; TBX2; RXRA; ID1; MYCL; RYBP; ZNF329; CBFA2T3; TCERG1; MAF; NR2F6; ZNF394; TOX3; WT1; ZFP36L1; MED13; ZNF587; ZNF331; AEBP1; L3MBTL1; MDM2; SSBP3; KLF4; SMARCA1; KAT2B; ZSCAN31; NR3C2; STAT4; NR2F1; SOX11; HHEX; MAFB; PAX8; RBPJ; CITED2; ZBTB20; PEG3; HOXB2