Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75530	Fostamatinib	GSE92742	MCF10A	Human	6h	10uM	EID0434

Response Information :

Types	Number	Response transcription factors
Up-regulation	109	RELB; CEBPD; TBL1X; SP110; RUNX3; SPIB; PBXIP1; MEOX1; BCL3; MNDA; EZH1; BRD8; MXD1; PSPC1; CBFA2T2; YEATS2; MYRF; TRIM29; DNAJC1; NR0B1; RELA; HMGB2; GON4L; NR2C1; RERE; ZNF467; CALCOCO1; ZBED2; PNRC1; JUP; NAB2; BAZ2B; PLAGL1; ZBTB17; KDM5D; ITGB3BP; ZHX2; ARNTL2; MZF1; FOXO4; ST18; IRF2; PHF20; FOXE1; RCOR1; ZMYM2; EMX2; TGIF1; NFKB2; ELF5; GTF3A; E2F2; HOXC10; RORA; PBX1; ZNF354A; IRF7; HDAC4; JAK2; SIAH2; TAF12; VGLL1; ERBB4; IRF9; LITAF; IRF8; GATA6; ZNF217; RBBP8; HMGXB4; HOXB2; SP100; HOXB6; ZNF148; ZNF45; KAT2A; TOB1; HOXB7; EHF; EN1; PFDN5; NFE2L2; TAF1D; ELF3; CBX5; BACH1; OSR2; SOX9; JUNB; HOXC6; TP63; MYCL; PAX8; SPDEF; ZIC1; DDIT3; NAB1; SMAD2; PEG3; CITED2; BAZ2A; YBX3; PDLIM1; INSM1; IFI16; ZNF331; NR2F2; CDK7; PSMD9
Down-regulation	102	ADRB2; LZTS1; ZNF443; IRX5; PBX3; POLR2A; STAT3; KLF12; HNRNPD; SREBF1; DACH1; ZNF107; ASH2L; RNF138; ZNF282; CLOCK; PLAGL2; ZNF232; SF1; BCOR; ERG; HEY2; ORC2; ZNF134; ZNF672; HAND1; CHD9; CCNC; ZNF292; MED7; CTNNB1; MAFG; RRN3; ZMYND11; TRIM24; RUNX1; NPAT; NPM1; SMARCD3; ZNF93; UBE3A; PHOX2B; PARP1; SUZ12; PURA; SFMBT1; ENO1; BCLAF1; RNF14; CSDE1; EGR2; PCGF2; E2F3; CERS6; TFCP2L1; BATF3; ZNF468; WHSC1; TBX2; ZNF85; GATAD2A; SMAD1; RCOR3; EPAS1; YWHAB; RBBP4; BACH2; HMBOX1; ZMYND8; PCGF1; NUP62; REPIN1; PAX5; GTF2I; C1QBP; TOX; BHLHE40; ETS2; ETS1; DNMT3B; BANP; MAFB; BCL11B; SOX10; BTG1; BCL11A; AEBP1; RREB1; LEF1; TWIST1; PSMC3; ID2; ZFP36L2; VPS72; VDR; TXNIP; NKX3-1; HTATIP2; SMARCD2; TFAP2C; FLNA; HEY1