Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75529	Vemurafenib	GSE92742	MCF10A	Human	6h	0.08uM	EID0434

Response Information :

Types	Number	Response transcription factors
Up-regulation	148	RELB; NCOR2; YBX1; FOXD1; PRKDC; RFX7; RNF14; EED; EP400; DLX5; PMF1; XRCC6; POU4F2; FOXA2; AGO2; NFKBIA; ZNF432; PIAS2; PPARGC1A; NFX1; KAT5; BCL3; NFE2; KMT5A; TAF4B; TAF9B; HOXA1; MED14; TCEA1; ENO1; KLF7; ERG; GATA2; FOSL1; ING2; ZBTB40; BMI1; RBBP7; HEY1; TSC22D4; ARNTL; YAF2; ASXL1; BLM; LOXL2; MKL1; HOXB7; HCFC2; KDM2A; ID3; PHOX2B; MAZ; SMAD2; ZNF24; TFDP2; MKL2; SREBF1; RNF141; TAL1; MED20; CBX3; ZNF84; TAF10; NR2C1; HLTF; HOXA5; ZNF266; CARM1; CAPN15; KDM5C; DLX2; KLF6; NCOA4; BTAF1; NONO; TRIM28; BRD8; GTF3A; ALX1; PEX2; EGR4; HDAC9; ZNF222; HIVEP2; FOXC1; MNT; FOXJ3; NPAS2; FOSB; TWIST1; ISL1; PPP1R13L; CBFB; FOXO3; TGFB1; ATF3; SFPQ; CREB3L1; NCOA6; NR0B1; KLF5; TSC22D3; JARID2; SMAD1; ATF4; MAGED1; NKX2-2; CBX6; NUP62; HOXC6; HIC2; HLX; HDGF; AFF1; ZNF226; SSRP1; ID4; ZBTB18; ING3; RAN; EYA2; TCF7; RNF111; XBP1; BCL11B; CNOT3; RUNX1; COPS5; ELF3; GABPB1; TBPL1; FOXO1; TFDP1; E2F5; DPF2; ASCL1; DDIT3; VPS72; EGR2; TCERG1; PSMD9; SOX9; RHOA; NAB1; BHLHE41; PUF60; RUVBL1; LEF1
Down-regulation	106	FHL2; MYCBP; CRYM; EHF; ZHX2; ZNF12; AR; DACH1; CERS4; FOXF2; TULP3; AFF2; ESR1; PHIP; ZNF22; PRDM12; ARID5B; TCEA2; MEIS2; OSR2; ARNT2; ARHGAP35; MSC; CITED1; FOXF1; UBP1; ITGB3BP; HLF; CTBP2; TEAD3; ZNF593; MNDA; ZBED2; TGFB1I1; PTRF; MYB; RBPMS; IRF7; ZNF184; MYBL1; CERS6; RBFOX2; BASP1; TCF21; TOX3; ERBB4; SOX10; UBE3A; ZNF611; SIAH2; TRIM22; ZFPM2; SALL2; CBX4; IRF9; OVOL2; PTTG1; MYCL; CD3D; TXNIP; JUP; WNT4; RYBP; BCL11A; NFE2L2; HOXD1; ZNF189; ZBTB20; ZNF580; ZSCAN31; IRF6; TRIP6; PEG3; SP3; PLAGL1; NANOG; TBL1XR1; BNC2; DAXX; WT1; ETV5; ZFP36L1; TOX; PRMT2; ZBTB16; CUX2; FOXL2; TFAP2C; ZBTB38; NFKB2; RREB1; ZNF43; NR2F2; NR2F1; MITF; AES; MDM2; GRHL2; STAT4; NR3C2; NR4A2; KAT2B; CREM; TBX3; ID2; E2F2