Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75517	Alvocidib	GSE92742	MCF10A	Human	6h	0.08uM	EID0434

Response Information :

Types	Number	Response transcription factors
Up-regulation	90	GATA3; CEBPD; TRPS1; CD3D; TAF7; DLX5; ATF3; HOXC13; GTF2F1; MYBL1; NAB2; HOXB1; PIAS4; HEY1; PHOX2B; ZNF195; SRCAP; CNOT3; RARG; DMTF1; ERF; HSF1; DEAF1; TBX2; ZNF467; MED15; MXD1; TCF25; RING1; PRRX1; SMARCA1; KDM5C; IRF6; RBFOX2; WNT4; YBX1; PHOX2A; TRIM29; HMGA1; TRIM28; SUPT6H; NKX2-1; SSBP3; TCF7; USP16; TGFB1; ZNF281; GLI3; MBD1; JUP; HDAC5; PAX6; AES; PFDN5; SHOX2; TP63; KLF6; HLX; TBX3; FOXF2; KLF7; BHLHE41; ISL1; ZNF512B; ST18; BACH1; SPDEF; ZEB1; SOX9; ID3; HOXC6; ELF3; PSMC3; EPAS1; HIPK2; PEG3; HIC2; ATN1; ID4; MAF; ZBTB18; IRF8; NFKB2; VDR; HOXC10; DAXX; CREB3L1; KLF10; SNAI2; PSMD9
Down-regulation	127	MYCBP; ADRB2; FHL2; CCNA2; ATF5; HOXA10; FOS; ZMYM2; TSC22D2; TFDP1; ZBTB24; BASP1; EZH2; POLR2A; HMGB3; HOXA5; ZMYND8; PHIP; TBL1X; MECP2; PHF2; HOXB6; SOX4; PATZ1; AFF1; PBRM1; TFAM; ARNT; SREBF1; PMF1; SIAH2; SFMBT1; RERE; ZNF124; RBBP5; TGIF1; RUNX3; INSR; ING1; CHD1; MAGED1; ZNF415; SOX13; ING3; ZHX2; TULP4; YAP1; BBX; CCNC; MITF; HOXB7; RBBP7; ELF1; BTG1; FOXJ2; MSX1; SMAD1; HSF2; ZBTB1; NPAS2; SOX17; NR1D2; BMI1; TOPORS; HDAC2; ZNF426; ETV5; REST; HOXA11; PIR; ZBTB38; TCF21; PHF8; KDM5D; PPARG; ZNF131; MYB; ZNF189; JARID2; GTF2IRD1; GATAD2A; ZBTB20; SFPQ; ZSCAN31; GABPB1; RREB1; NFIB; SMARCE1; KLF2; ZBTB16; RLF; TOX3; BTAF1; ZNF329; ZEB2; MED1; SMAD5; DDX5; CHD7; BRD2; ZFP64; SMARCA2; NR2F2; FOXO1; PBX1; TFCP2L1; CRY1; HTATIP2; HDAC1; EGR3; HMGN3; GATA6; RHOA; PDLIM1; TOB1; CEBPA; ZNF516; DPF2; SOX11; DNMT3B; SAP30; KLF4; BRCA1; ZNF652; SATB2; EMX2; E2F2