Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75514	Alvocidib	GSE92742	MCF10A	Human	6h	10uM	EID0434

Response Information :

Types	Number	Response transcription factors
Up-regulation	152	ZMIZ1; NR0B2; SOX2; LZTR1; RING1; HDAC6; ZNF83; KDM5C; HDAC9; MED14; BARX2; NHLH2; PBX2; TCEA2; NR1H2; NEUROD1; HINFP; ZNF586; ATF3; AFF2; GFI1B; MXI1; PRDM12; MEIS2; HIF3A; TRIM22; KLF13; ST18; ZFPM2; SP100; VGLL1; CERS4; CNOT3; EHMT2; ZNF117; INSM1; SUPT3H; ZNF467; MEIS1; ERBB4; SSBP3; ZBED2; ZNF141; ARNT2; MXD4; TRPS1; ZNF512B; IRF7; SMARCA1; TTF2; CSDE1; CREBL2; ZNF816; ZNF835; TCF7L1; ZNF768; SSBP2; LHX3; ESRRG; SUMO1; ZNF224; RARG; TGFB1; DBP; SOX17; ZNF264; BNC2; ZNF423; ID4; CNBP; NOC2L; ILF2; ZNF91; TAF11; KLF7; WDR77; NFE2; VPS72; ING4; CREB1; SIM1; DACH1; IRF9; TBX21; SREBF1; ZNF93; HSF1; NFATC3; GCFC2; EMX2; MED12; TADA3; TCEA1; SRF; MYCN; SPDEF; CREB3L2; IRF3; ZNF43; NFE2L3; ZNF665; SPIB; SLC2A4RG; TBX2; UBE2L3; PEX14; TRIP4; DLX2; HOXD1; HIRA; KAT2B; TFEC; NFIC; MED15; IRF8; ZNF232; WNT4; TCF21; C1QBP; HDAC5; NFE2L1; HIPK2; NR2F1; CDK2; ETS1; MTA1; JUP; AES; CITED2; HOXB6; TRIM29; SHOX2; AR; JAK2; ZNF331; MECOM; ZIC1; NKX2-1; PBX3; KLF11; IRF6; PIR; PEG3; HOXB2; TFAP2A; ZSCAN18; LITAF; PSMC3; KLF9; ZNF430; FLNA; PSMD9
Down-regulation	310	MYC; ADRB2; NFKBIA; CCNA2; SUV39H1; KAT6A; FOS; HOXA10; HOXA5; FOXO3; FOSL1; CEBPB; ARID4B; CRK; SFPQ; USP22; MTF2; ZBTB24; TGIF1; TLE1; CHD1; BIRC2; TRIM32; NCOA4; TAF1A; ZNF324; PLAGL2; SAFB2; PATZ1; FOXJ3; TSC22D2; ADNP; ZNF131; ZNF443; ZMYM2; CEBPD; ETS2; ZNF146; ING2; BRD8; RFX5; DNAJC2; MAX; CDYL; ZBTB1; TBP; ZHX2; MAGED1; ZNF12; XBP1; FHL2; FOXA1; RBM14; VGLL4; E2F3; ZNF672; MGA; CRYM; BCL10; KDM5A; ELF1; MED7; ZNF629; ZNF200; KLF2; SMAD7; ADNP2; SMAD1; MLX; AFF1; BCLAF1; RUNX3; BAZ1B; ZBTB38; ATF5; ZNF248; SUB1; NUP62; NFKB1; SMARCE1; NFIL3; NRBF2; JARID2; RNF4; IRX4; TFAM; ZNF7; RNF6; MED6; PHF20; STAT3; TRAF6; UIMC1; HOXA11; HMGB1; ZFP30; REST; TRAK1; ERBB2; SETD2; SIAH2; SOX9; ZNF473; ITGB3BP; RBBP4; TEAD1; POLR2A; TBL1XR1; BRPF1; EED; CEBPZ; ZSCAN32; SATB2; HNRNPD; PTTG1; PCGF2; BAZ1A; CXXC1; SMARCD3; MAFG; CCDC59; MTF1; ZNF267; TSC22D1; DDX5; ZBTB43; TAF4; RBBP5; ZNF107; UBE2I; HOXA1; HES1; AGO2; TRRAP; ZSCAN12; ZNF410; DDX54; TOPORS; SUZ12; NKX3-1; LOXL2; YWHAB; HIVEP2; BASP1; CTNNB1; TCERG1; ATF1; NFIB; ZNF408; BTF3; PSPC1; ABL1; ZSCAN5A; ZNF764; PARP1; HOXA7; CENPF; CTR9; HMGB3; HDAC4; ZNF189; FOXC1; BCOR; RNF138; SIX1; BRD3; TAF9; PHF2; CLOCK; ELF2; BANP; ZNF263; ZBED4; CCNC; ZNF3; SIX2; WWC1; ELK3; PIAS2; SNIP1; PBRM1; POLR3F; SNW1; MSX1; AATF; HSF2; ZNF16; ERG; MKL2; TTF1; ZFP36L2; ING3; NR1D2; TCFL5; BTG1; CCNE1; VEZF1; MYB; PHF8; ARID5A; RLF; HMG20A; RREB1; ZNF721; ZFP64; DPF2; KMT2A; PQBP1; E2F6; HOXD10; BAZ2B; HDAC1; MED1; NFATC1; BRD2; KDM5B; PRRX2; SMAD3; MED13; CRY1; TRIM16; ARNTL; TSC22D4; ZBTB16; SOX4; BMI1; NPM1; TRIM27; PURA; EP400; HOXD11; RUNX1; HMGB2; PPARGC1A; SP3; CCNH; ZBTB11; NR3C1; ZBTB40; JUNB; CBFB; IRF2; EGR3; TCF20; TERF2; ZNF148; HOXC6; GTF2IRD1; HSBP1; CREBZF; KDM2A; HOXB7; TBPL1; SFMBT1; TULP4; UBE2B; TCF7; NPAT; EZH2; ZNF302; ETV5; CHD7; BATF3; CBX5; POU2AF1; SMAD2; NR3C2; DNMT3B; SMARCA2; SF1; ESR1; ZMYND8; SMAD5; PAXBP1; CENPB; NR0B1; DMTF1; RNF111; MITF; HLTF; RBPJ; IRX5; ZNF14; FOXD1; KLF6; ID1; SAP30; HLF; PMS1; ZNF516; HTATIP2; NRIP1; KAT7; THAP10; TFAP2C; PDLIM1; MAFB; TOB1; HOXB13; BRCA1; KLF10; NLK; NR2F2; ZBTB20; ID2; SNAI2; TBX3; LEF1; CDK7; E2F2