Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75509	Roscovitine	GSE92742	MCF10A	Human	6h	0.08uM	EID0434

Response Information :

Types	Number	Response transcription factors
Up-regulation	145	FOXC1; ECD; ASH2L; CXXC1; LMCD1; ASXL1; MYBL2; TRIM28; NFKBIA; PRKDC; NR1H2; AGO2; NFX1; RFX7; NELFB; DNAJC1; CRK; USP22; TRIM25; AFF4; YY1; TMF1; ZNF276; SREBF1; RUNX1; MKL1; TAF1; RUVBL2; CAPN15; MEF2C; HEY1; SKI; IRF3; ENO1; IL16; GATA4; BLM; HOXA5; CTR9; HOXC6; ZEB2; SMARCB1; GATA2; ARNTL; MED6; KDM5C; ID3; NUP62; ERF; TGIF2; ELF1; SFPQ; PHOX2A; ATF7IP; IRF5; EGR1; KDM2A; TEAD1; CNOT3; RBM14; NFIB; KLF6; C1QBP; FOSL1; ORC2; AATF; GTF2I; BATF; TAF10; PPRC1; FEV; HOXC8; TRIP6; MXD4; SMAD5; TGFB1; STAT3; MAX; TXNIP; SPIB; TWIST1; LIMD1; TRPS1; EPAS1; PHOX2B; MNT; BAZ2A; HIVEP2; MED1; INSR; PPARGC1A; CARHSP1; HTATIP2; ZFP64; ASCL1; ELF3; XBP1; CBFB; HNRNPD; TFDP1; TSC22D4; PML; PROX1; POU2F2; MAFG; UBE2I; KMT2B; BHLHE40; LYL1; FOSL2; HOXA1; IRX5; MSX1; ETS2; TRIM29; MEF2A; BMI1; CRY1; SMARCD2; ID1; PBX3; KLF2; NCOR2; KLF7; FOSB; BTG1; JUNB; SMARCA2; EGR3; HLX; NR1D2; DDIT3; PDLIM1; MTA1; FLNA; PSMD9; CREB3L1; RUVBL1; NR2F6; SMARCC1; PUF60; CALR; SNAI2; RBPMS; SOX9
Down-regulation	197	DRAP1; PHIP; ZNF12; TBL1X; TCEA2; ARID5B; ZNF500; PIAS1; IRF1; BASP1; HIVEP1; NFE2L3; CRYM; MYBL1; IKBKAP; MECP2; ATF5; CD3D; TEAD3; TCEB2; HIPK1; CLOCK; CALCOCO1; ITGB3BP; RUNX3; CERS4; ZHX2; SP3; TGIF1; TDP2; ZNF654; PITX2; GMNN; ZNF467; ZNF184; FOXA1; BNC1; TCF25; SOX13; MAK; CTBP2; CBX7; KDM5D; ZNF586; ZNF22; ZFPM2; ELF2; FOXF1; ZNF415; TAF7; TOX3; ZNF324; TRIB3; NEUROD1; HDAC4; KDM4C; SOX12; TCF7L1; RERE; ZBTB16; GTF2IRD1; PIAS4; WT1; HMGB1; TOPORS; NFYB; ADNP2; ZSCAN9; URI1; TRIM22; ZNF268; ZNF3; ZNF423; FOXF2; MYCL; ZNF274; STAT4; ZNF239; NFE2L2; ZNF492; ZNF606; PFDN5; MEOX1; ZNF180; MYB; CREBL2; SSX1; TGFB1I1; RRN3; ZBTB18; SALL2; PKNOX2; ESR1; OSR2; ZNF571; RREB1; BACH2; TULP3; ELK4; ZNF354A; ARNT2; JUN; KAT2B; MNDA; POU2AF1; CNOT6; AR; CCDC59; TCF21; LOXL2; ZNF140; IRF2; SRCAP; HOXD11; ZNF148; DLX4; ARID1A; ZNF350; HLF; ZNF43; ZNF75D; JUP; MED23; ZNF257; PHF1; ZIC1; ZNF711; ZSCAN31; ZNF468; MXI1; JAK2; EZH2; FOXN3; MED20; TCF4; ZNF263; MEIS2; ZNF329; EHF; ZEB1; DEK; ZNF611; ZFP36L1; FOXG1; BNC2; TLE2; CBX5; SOX11; SETDB1; ZNF83; CCNE1; DAXX; NKX3-1; HIRA; KLF11; RBPJ; SMARCC2; TFDP2; CBFA2T3; MEOX2; HOXB13; IRF9; ZMYND8; MED13; ZNF32; ZBTB20; ZSCAN18; TFEC; NANOG; ERBB4; TP63; HBP1; CUX2; ZNF302; GRHL2; IRF6; LPIN2; ZBED2; CUX1; CNOT2; ZZZ3; LEF1; SMARCA1; CITED2; ETV5; HOXB2; ZNF217; MAFB; SUB1; NR3C2; MEIS1; INSM1; ID4; NFKB2; TFAP2C; NR2F1; E2F2