Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75508	Roscovitine	GSE92742	MCF10A	Human	6h	0.4uM	EID0434

Response Information :

Types	Number	Response transcription factors
Up-regulation	113	MYBL2; HEY1; YY1; XRCC6; NFIB; PRKDC; NFKBIA; TRIM28; REXO4; SCAND1; CRK; NELFB; KLF7; SPIB; RUVBL2; GATA4; CCNT1; KMT5A; PA2G4; HOXC6; TGIF2; SMAD1; CARM1; TDRD3; ID3; MSX1; SREBF1; TSC22D1; CAPN15; BHLHE40; DNAJC1; ZBTB18; MTDH; EGR1; ENO1; KLF5; SMAD5; ERF; MAZ; TGFB1; MED1; PAX5; AATF; NR1I2; NKX2-2; FOXG1; HMGA1; FOXA2; BLM; PHOX2B; KMT2B; TP53; BBX; TOB1; GLI3; PROX1; TSC22D3; ZNF576; FLNA; MLX; ARNTL; INSR; ASCL1; CBX6; XBP1; PAX6; SATB1; NR1D2; CNOT3; ETS1; IRX5; CBFB; NUP62; HMBOX1; PTTG1; ELF1; NCOR2; NR1H3; EYA2; CEBPG; BMI1; KLF9; BATF3; IKZF5; HLTF; BAZ2A; DLX2; MAFB; BCL11B; ELK3; CREB3L1; C1QBP; PBX3; HOXB7; EPAS1; SMARCA2; CALR; ATF4; NKX2-1; INSM1; SAP30; MED24; PSMD9; SNAI2; SATB2; TXNIP; POU4F1; ID1; HTATIP2; PDLIM1; BHLHE41; NR2F6; RUVBL1
Down-regulation	113	GTF2A2; MNDA; HMGA2; HIF1A; ZNF12; TCEA2; KDM5D; ZKSCAN7; HIVEP1; ZNF248; PHIP; CRYM; ZSCAN9; PLAGL1; ARID5B; ZNF239; TFDP1; CDK7; TGIF1; SMARCD3; HMGB3; ERBB4; RREB1; KLF1; WT1; HMGB1; TEAD3; AR; SUMO1; NFE2; ZNF22; ZNF423; ITGB3BP; ZNF415; SIAH2; SOX17; TRIM22; ZNF117; ZFPM2; ZNF467; NFE2L2; TAF11; MYBL1; ZKSCAN4; HDAC2; E2F8; ZNF571; TEAD4; ZNF544; IRF9; GTF2IRD1; SOX11; ZBED1; OSR2; ZNF329; ZNF257; COPS2; ID4; NFE2L3; ESR1; ZNF85; ZNF93; ZSCAN16; STAT4; CCNE1; DACH1; BACH1; THAP10; CREBL2; CBX7; NCOA1; ZSCAN31; ZFHX3; TAL1; JUN; ZNF43; CITED2; RLF; RSF1; CBFA2T3; ZSCAN18; NR4A2; ZNF136; ZNF350; BNC2; HOXB2; MDM2; DAXX; TAF9; MYB; HLF; PIR; ZNF331; YBX3; CUX1; ZNF711; SP140L; PEG3; MEIS2; FOXF1; ZZZ3; TFEC; KLF4; NFKB2; GRHL2; MYRF; SALL1; BCL11A; EMX2; ZFP36L1; CREM; TFAP2C; E2F2