Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75506	Roscovitine	GSE92742	MCF10A	Human	6h	10uM	EID0434

Response Information :

Types	Number	Response transcription factors
Up-regulation	110	MYBL2; SCAND1; CRK; KLF5; HMGA1; ZFHX4; PTRF; PRKDC; KMT2B; YY1; SMARCB1; NFIB; PPARD; CARM1; UBTF; NFKBIA; TSC22D4; CXXC1; NCOR2; VPS72; TGFB1; CAPN15; TRIM28; RNF14; TWIST1; BRPF1; LOXL2; ASXL1; TXNIP; ID1; NR1I2; MED15; TAF10; FLNA; BHLHE40; FOXC1; SPIB; RUNX1; PPRC1; AATF; ZNF131; KLF7; FOXA2; MAFG; CITED1; RUVBL2; MLXIPL; HOXA1; TRIM25; PHOX2B; ID3; ARNTL; CTR9; DLX2; TRIM29; SATB1; CNOT3; TOB1; MNT; FOXD1; NRBF2; PA2G4; HOXC6; EPAS1; UBE2L3; NUP62; KLF6; SMAD1; KDM2A; SMAD5; MYRF; HEY1; BAZ2A; MLLT10; CBX6; PML; MLXIP; NR1H3; TSC22D3; GTF2I; MED1; SOX4; CBFB; YWHAB; SSRP1; ZBTB7A; PAX6; TFDP1; ZNF281; HTATIP2; SMARCD2; ELF1; LITAF; DDIT3; BANP; DPF2; C1QBP; BASP1; BRD4; PAX5; ELK3; PBX3; SNAI2; TERF2; PDLIM1; PSMD9; NR2F6; CREB3L1; ZIC1; RUVBL1
Down-regulation	136	IKBKAP; MNDA; PHIP; TBL1X; CRYM; ZNF248; TCEA2; SOX13; ECD; SOX17; FHL2; ARID5B; HMGB3; CREBL2; NR4A2; CHD9; ZNF124; HIVEP1; ZNF467; NR4A1; GTF2A2; ERBB4; STAT1; HDAC2; MED23; NR4A3; ZNF184; FOXA1; SP3; CCNA2; TGIF1; ZNF12; ZNF571; SMAD4; HLF; ZNF107; TRIB3; PLAGL1; ZNF239; SOX11; JUN; HEY2; ZNF331; NFE2L2; WT1; CBX7; HDAC4; ZNF415; TAF11; ZSCAN31; FLI1; CERS6; CCNC; NFE2L3; HMGB2; JAK2; CERS4; PIR; RREB1; PCGF3; AR; ZNF135; BCLAF1; SCMH1; ITGB3BP; SIAH2; ZNF274; KLF4; IRF9; SMARCD3; CLOCK; ID4; MED21; ZNF544; REL; EZH2; PITX2; TBL1XR1; RSF1; THAP10; PKNOX2; NR0B1; ZNF304; TOX3; TFEC; ZNF512B; SALL1; APEX1; ZBED2; CD3D; NR1H4; TCF21; SMAD6; REPIN1; ESR1; HOXB2; WWP1; MYCL; FOSB; ZSCAN18; KDM5D; ZNF93; HMGN3; MEIS2; NCOA1; ETV5; TEAD4; SATB2; NFKB2; MAF; ZNF329; ZNF83; STAT4; RBPJ; BNC2; CBX5; BCL11A; SMARCA1; HOXC10; TCF4; MYB; KAT2B; GRHL2; KLF11; EGR3; CREM; FOXF1; RYBP; POU4F1; EMX2; ZBTB16; NR3C2; NKX3-1; TFAP2C; LEF1; ZFP36L1