Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75492	Tak-715	GSE92742	MCF10A	Human	6h	2uM	EID0434

Response Information :

Types	Number	Response transcription factors
Up-regulation	134	RBBP7; MYT1L; HOXC6; HOXB7; CBFB; RNF14; TAF10; NKX2-2; TSC22D4; SCAND1; ASXL1; POU4F2; KDM5B; MLXIPL; RNF6; ERF; NR1H3; GATA4; PREB; CTR9; GATA3; RNF141; HOXA1; TMF1; CRK; ELK1; EGR3; MSC; HOXA5; BLM; SMAD3; TAF9B; PIAS2; PPARGC1A; ZNF189; BATF; IRF5; ASH2L; HOXB9; ORC2; SMAD5; POU2F2; MYBL2; KDM5C; MSX1; EED; PROX1; FOSL1; HOXC4; E2F6; SFMBT1; ZNF302; CCNC; HABP4; FOXO4; ZBTB32; NFIB; SP140; EGR4; TEAD1; LMCD1; AATF; HOXD10; MED7; CBX6; RUVBL2; KMT2B; NR2F2; ZNF23; MYCN; HMGN3; ENO1; BRD8; AFF1; RBBP4; POLR2A; SETD3; NR0B1; JARID2; CAPN15; ZBTB38; PTRF; KLF9; CHD7; TRIP6; FOXG1; BRD3; SND1; ASCL1; HOXB6; ATF1; C1QBP; XBP1; CARHSP1; ZNF226; BMI1; C1D; ZNF432; ZBTB18; GTF3A; PEX2; KDM2A; TGFB1; TP53; PAX5; TAF1D; MED1; TSC22D3; DNMT3B; NCOA6; EMX2; HLTF; SOHLH2; CRY1; MAF; TBP; MEF2A; KLF7; BHLHE40; TSC22D1; HTATIP2; HEY1; NFAT5; RHOA; FLNA; MAFB; ST18; BCL11B; ELK3; RUVBL1; PDLIM1; WT1; HDAC2; PARP1
Down-regulation	166	DNMT1; ZHX2; ARNT2; FOXF2; TCEA2; ZNF12; TRIB3; PHIP; MYBL1; MNDA; ARID5B; TRPS1; ZNF423; AFF2; ZNF586; HIVEP1; ZNF654; NFE2L3; TLE4; REL; ZNF500; PIAS1; ZEB1; HEY2; GMNN; KLF3; CBX7; NFE2L2; SIX2; TCF4; RAD21; ERBB4; SMAD7; CHD9; TGFB1I1; BCL11A; HIPK1; ZNF444; FOXF1; SNAPC4; ZNF117; TULP4; ZBED2; TRIP11; ZNF611; ZNF304; KDM4C; TCF21; TRIM22; ZNF551; SSBP2; TOPORS; HOXD1; FOXI1; SP3; ZNF274; ZNF273; PQBP1; AES; JUN; ZNF44; ZNF217; ZFP69B; HIC2; NPAS2; SMARCD3; MYB; RSF1; ZNF184; MEIS2; TBX3; TCF7L2; PLAGL1; NFYC; ITGB3BP; PSMD9; ZNF467; DEK; TRIM29; IRF7; JAK2; ZSCAN18; EHF; CNOT6; ILF2; LYL1; ZNF711; NR4A1; GTF2F1; EP300; ZNF160; PBX3; HIRA; AEBP1; IRF9; TRIM24; TFAP2C; ZNF180; WNT4; ZNF329; ZNF14; ATF3; ZNF512B; DAXX; SIM1; TBX2; NKX2-1; ZNF43; PRDM1; ZNF331; ZNF350; SIAH2; MKL2; EN1; CNOT2; THAP7; CUX1; POU2AF1; SIX3; SPDEF; TOX3; RFXANK; NR3C2; CBX4; FOXE1; REPIN1; E2F5; ZNF136; SKIL; PAWR; IRF6; HDAC1; NFKB2; SMAD6; CDK2; SP140L; ZNF24; ZFP36L2; TCF7; KLF11; IFI16; SOX11; TOX; NR4A2; ID1; BHLHE41; KLF4; OSR2; RREB1; ZEB2; CAMTA1; ZNF430; PSMC3; AHR; MYCL; SOX10; AR; KAT2B; VDR; ZNF652; GRHL2; ZNF91; CREM; PEG3; NKX3-1; E2F2