Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75454	Palbociclib	GSE92742	MCF10A	Human	6h	0.4uM	EID0434

Response Information :

Types	Number	Response transcription factors
Up-regulation	133	SOX2; TCFL5; ZNF589; EGR1; ZNF532; ERBB2; IKBKAP; ZNF423; RFX7; RARB; PATZ1; OLIG2; MYRF; HOXB6; NFIX; AGO2; NR3C1; LZTS1; NR0B1; PHF2; ZNF580; FOXN2; SIX2; BPTF; POU5F1B; EP400; ZNF536; NEDD8; ISL1; TRIM28; CHD7; ZNF146; ZNF460; HCFC2; TBL1X; IRF8; PRKDC; NKX2-2; FOXD1; SALL2; ZIC3; FOXA1; USP21; CDK9; FUBP1; RNF10; MNDA; TRIP6; PMF1; PBX1; USF2; NFYA; ZNF143; EBF2; POU3F2; SIAH2; MZF1; HIPK3; ATF7IP; TP63; FOSL1; SUB1; HDAC9; TOX3; CREB5; SREBF1; SIRT7; HOXD10; DMTF1; ZNF34; E2F2; TXNIP; ERF; CBX6; NUP62; SIX1; ZEB2; MTA1; SPIB; HDGF; ATF6; HIVEP2; SMAD5; TCF12; HOXC6; MED24; ZNF24; PCGF2; FOSL2; KDM5D; TLE4; ZNF516; HOXB7; SETDB1; RNF141; MSX1; CENPF; MEOX2; FOXG1; NAB1; ATF3; KLF11; MAFB; THAP7; NCOR2; BATF; HMGA1; SKIL; SOX11; TRIM16; TCERG1; STAT6; JARID2; TBL1XR1; HOXB2; FOSB; JUND; MDM2; SMARCA2; INSM1; CREB3L1; HOXC10; GABPB1; HLTF; EGR3; PAX8; VPS72; IFI16; PITX1; SATB2; RHOA; PSMD9; NR2F1
Down-regulation	183	DRAP1; TCEA2; SUZ12; FHL2; NFE2L2; PSIP1; ING2; MYBL1; ZNF44; PQBP1; ZNF12; CCNH; SAP130; ZNF667; ZNF426; DACH1; ITGB3BP; GATA6; NFE2L3; ZNF43; CTBP2; CDK7; ZNF721; CHAF1B; HBP1; ZNF492; ZNF93; ZNF611; E2F3; ATF1; ZNF665; CCNE1; IRF7; CEBPB; TRPS1; ZFX; TGIF1; E2F8; ZFP30; HHEX; TCF7; RBL1; BCL10; HMGB1; TRIM33; TULP3; ZNF160; SMAD7; CHD1; STAT1; ZNF117; CREB1; WT1; CITED2; BASP1; CBX3; ARID4A; PAWR; PSMC3IP; TSC22D2; ZMYND8; PHIP; SMARCC2; ZNF652; ARID1A; KDM5C; ARNT2; NR4A2; PITX2; AEBP1; SIM2; ERG; ID1; ZNF562; ZNF224; ZNF91; ZNF430; ZNF331; TCEB2; NPM1; URI1; HSBP1; CDK8; ZNF85; ZFPM2; UBE2B; REL; CDX2; KLF4; KAT6B; CEBPG; MGA; MED17; BLM; SP100; NFE2; RNF6; ZNF551; ZBTB20; ZNF468; THAP10; TULP4; MECOM; IRX4; EDF1; CTCF; NPAT; PRRX1; ID4; MBD2; ZNF273; NPAS2; ELF5; CLOCK; L3MBTL1; TAF5; ZNF544; NR2F2; TCF7L2; CBFB; LOXL2; WWC1; BRD7; ZNF136; ENO1; ID3; LEF1; BANP; COPS2; KLF6; RCOR3; TBX2; SMARCD3; RLF; NFIB; LYL1; TRIM22; ZNF512B; TFDP2; ZBTB16; BRCA1; ZNF593; BCL11A; ING3; SOX4; ZNF232; NFKB2; PSMC3; DLX2; TCF21; MED13; ZNF302; ETS1; SP140L; BHLHE40; ZNF264; RBBP8; MXI1; HIC2; ID2; TOB1; SMARCA1; SSBP3; FOXF1; DAXX; EPAS1; ZSCAN18; TWIST1; PAX5; CUX1; ZNF217; VDR; TOX; GRHL2; FLNA; MYB; ZFP36L2; KLF10; BHLHE41; MEF2C; EMX2; TFAP2C; NFKBIB