Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75451	Osi-027	GSE92742	MCF10A	Human	6h	0.08uM	EID0434

Response Information :

Types	Number	Response transcription factors
Up-regulation	125	ASH2L; PPARGC1A; AFF1; ING3; RELB; MEF2C; SMARCB1; NFE2L1; BRD8; ERBB2; HOXC6; AGO2; HTATIP2; ARNTL; NCOR2; SCAND1; TCEA1; DNAJC1; PBRM1; ZNF226; ZBTB40; MAZ; USF2; ZFP64; MEF2A; PIAS2; ARID4A; TAF10; BMI1; PMF1; HIVEP2; MKL2; RNF14; BLM; FOXO4; SKI; TSC22D4; STAT3; SMAD3; NPAT; ETV1; HMGB3; KLF6; TRPS1; TRIM28; ERG; NR2E1; TCF4; TSC22D3; LMCD1; BRF2; YBX1; BRD3; MAGED1; HOXA1; HOXA5; SOX4; NUP62; TMF1; HLTF; SPIB; KDM2A; ATF1; HEY1; HOXB7; MTDH; KLF9; FOXC1; FOXO1; NR3C1; TXNIP; RNF141; HMGA1; BATF3; ENO1; POU3F2; IRF5; DNMT3B; ELF1; CRY1; NCOA6; FOXG1; CEBPG; BTG1; KLF7; MNT; MLX; FOXD1; PDLIM1; HDAC1; NR1D2; SMAD2; MSX1; EDF1; RBBP8; TP53; PTTG1; HDAC5; PAX5; NFIB; ZBTB38; ATF4; ASCL1; SSRP1; BRCA1; TERF2; VEZF1; KLF2; PIR; NFAT5; ID3; JUND; MED1; MYB; STAT6; RUNX1; RHOA; SMARCA2; PSMD9; PBX3; RBPMS; HDAC2; LEF1; RUVBL1; CDK7
Down-regulation	122	MYBL1; ZNF654; MNDA; ARNT2; PIAS4; SOX13; PHIP; ZNF467; ZNF12; PBX2; EYA1; ARID5B; ZNF586; ISL1; WT1; FOXF2; ZBED2; ZNF273; ILF2; SIX2; TRIB3; TCEA2; ZNF512B; HOXD1; BCL6; PIAS1; RARA; JUN; WDR77; ZNF423; MECP2; PCGF3; APEX1; NEUROD1; TRIM29; ZBED4; ZNF83; ZNF682; GTF2IRD1; SOX17; CRYM; NFE2L3; PQBP1; PLAGL1; NFE2L2; RBFOX2; STAT4; MED21; ZNF91; SMARCD3; MEIS2; ZNF239; TCERG1; OLIG2; BACH1; ZEB1; VGLL1; CNOT6; EHF; IRF9; HDAC4; PITX2; CD3D; NPAS2; ZNF43; WWC1; ZNF75D; ID4; HIPK1; FOXF1; TOPORS; HIRA; DAXX; ZNF665; REL; RXRG; ZNF136; PFDN5; TEAD3; CCNE1; ZNF180; OSR2; EYA2; GTF2I; URI1; SALL1; ETV5; CUX2; NR1H4; RREB1; ESR1; CTBP1; AHR; NFKB2; GATAD2A; SPDEF; SOX11; TFAP2C; HOXD3; GRHL2; GATA6; MYCL; IFI16; TCF21; TBX3; BCL11A; BHLHE41; ZSCAN18; HOXB2; AR; BASP1; HOXC10; KAT2B; NR2F2; ZNF331; ZFPM2; TRIM16; HHEX; SMARCA1; NKX3-1; ID2; E2F2