Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75449	Osi-027	GSE92742	MCF10A	Human	6h	2uM	EID0434

Response Information :

Types	Number	Response transcription factors
Up-regulation	117	SSBP2; HOXC6; RELB; FOXO4; NFIB; TSC22D3; ZMYM2; NR1H3; SPIB; SCAND1; LOXL2; BRD8; STAT3; KLF2; KLF9; ASH2L; TSC22D4; PBXIP1; KLF6; TSC22D1; TCEA1; ERG; SMAD3; ATF3; HOXC4; PTTG1; SLC2A4RG; ETV1; ARID4A; HIVEP2; PTRF; SKI; NCOR2; PMF1; FOXD1; PEX2; YBX1; MTA1; DDIT3; BCL3; TAF10; MAGED1; ZNF131; MLXIPL; MAF; BRPF1; MED15; TGIF1; BRF2; TBPL1; NRBF2; SMAD1; ENO1; KDM5D; RBL2; PEG3; HMGA1; ZBTB16; ZBTB18; MEF2A; HDAC1; RNF141; MNT; SMAD5; CBFB; ZNF302; SMARCE1; MAFB; HMBOX1; HMGB2; COPS5; SOX4; JARID2; CNOT1; NFATC1; FLNA; ELF1; HSBP1; BCL11B; ATF1; NAB1; BHLHE40; BATF; ZMYND8; ZNF226; BAZ2A; SAP30; NR1D2; WWP1; MED1; HMGN3; SMARCA2; DNMT3B; BAZ1A; TBL1XR1; RBPMS; PBX1; YBX3; HEY1; FOXG1; BHLHE41; TGFB1; CALR; EGR3; MITF; ATF4; PIR; POU2AF1; MXI1; PDLIM1; SOX9; HTATIP2; FOXO1; RHOA; ID3; IFI16; CDK7
Down-regulation	110	TRIB3; MNDA; ARNT2; ZNF586; ZSCAN9; PLAGL2; ZNF423; PIAS4; REL; NR4A3; ZNF124; DACH1; CCNE1; ARID5B; MGA; TCEA2; ANKRD1; ILF2; ZNF665; NR4A2; ZNF551; ZNF444; E2F8; WDR77; ZNF215; DLX5; HAND1; CRYM; ERBB4; ZNF180; ZNF331; PSMD9; MEIS1; HOXB5; ZNF611; NFATC4; WWC1; MEIS2; FOXI1; SOX17; RNF138; MED17; HOXB6; NFE2L2; HMGB3; ZNF239; ZNF43; INSR; HIPK1; SIX2; NR4A1; TCF21; MKL2; SMAD7; BASP1; ZNF45; IRF6; SMARCD3; ZNF576; TBX2; CREB1; VGLL1; ZFP36L2; SMAD6; TEAD4; FOXF2; ZNF263; AHR; BRIP1; MECOM; PRDM1; ZNF652; TCF12; ZNF136; NFKB2; ZFHX3; AR; HDAC2; MYCL; ZNF91; ZBED2; SOX11; KLF4; ST18; ELF3; HIC2; ZNF512B; CDK2; ZZZ3; ZNF160; ZNF430; ZNF232; RYBP; HOXD1; PSMC3; WT1; ESR1; ATN1; RREB1; CREB3L2; ETV5; GRHL2; ETS2; MDM2; BCL11A; TLE2; CREM; EMX2; ZFP36L1; E2F2