Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75394	Gsk-461364	GSE92742	MCF10A	Human	6h	2uM	EID0434

Response Information :

Types	Number	Response transcription factors
Up-regulation	161	MYBL2; SCAND1; RUVBL2; ASXL1; TAF10; RELB; NFKBIA; RNF141; HOXC6; CRK; EGR4; PPARD; CXXC1; AFF4; ARNTL; EGR1; POU3F1; CARM1; YBX1; ENO1; KDM2A; HEY1; HIVEP2; NUP62; USF2; KLF5; BLM; AGO2; CBFB; BRPF1; TRIM25; ERF; TRIM28; ELF1; HCFC2; RELA; SKI; TEAD1; PIAS2; CTR9; ORC2; ZHX3; MNAT1; SMAD5; ING1; NKX2-2; ID3; ZFHX4; KMT2B; FOXC1; FLNA; TSC22D4; TGFB1; BATF; KDM5B; POU2F2; SIM2; NR2E1; MEF2A; HOXA5; KLF7; AIP; STAT3; KLF9; TCFL5; CBX6; RFX2; SPIB; RBL2; KDM5C; AATF; ZBTB32; IRF5; FOSL1; ERG; ZFP64; MXD4; NFATC1; MAZ; PA2G4; FOXD1; DNAJC1; RUNX1; IL16; PTRF; RNF14; NPAT; HOXC4; PDLIM1; KLF6; CCNC; HOXA1; MAFG; TDRD3; POU3F2; MNT; FOXG1; MBD2; NR1H3; GTF3A; TMF1; HLTF; MED15; CNOT3; NCOR2; PROX1; LIMD1; CHD4; HMBOX1; TAF9B; BRD8; NFIB; MAGED1; MAFF; TSC22D3; BHLHE40; ELF3; PML; BBX; WWC1; ID1; EGR3; TWIST1; HOXB7; BAZ2A; NCOA6; EPAS1; SFPQ; MTDH; TBPL1; TSC22D1; TFDP1; SMAD3; MED1; JARID2; BRCA1; ETS1; HMGN3; SMARCA4; GABPB1; SMAD1; SMAD2; TOB1; CALR; VPS72; DNMT3B; ZNF281; BAZ1A; ELK3; ASCL1; MAFB; NAB1; ZIC1; MTA1; PAX5; HTATIP2; SMARCC1; SOX9; PUF60; RUVBL1; EMX2
Down-regulation	185	MNDA; ZNF12; GMNN; PHIP; ARNT2; TCEA2; ZNF586; ARID5B; DNMT1; TRIB3; IKBKAP; NFE2L3; ZNF274; ZNF268; CHD9; CD3D; ZFPM2; JUN; ZNF544; IRF1; CBX7; PIAS4; ZNF140; BACH1; CREBL2; ZNF532; FOXN3; TDP2; HIVEP1; WT1; ZNF184; CRYM; COPS2; CERS6; MYBL1; CTCF; ZNF682; RRN3; ZSCAN9; ZHX2; MEIS2; ZNF467; AFF2; TAF7; TGFB1I1; CDIP1; TEAD3; TCF21; SOX13; JAK2; ZNF423; STAT1; AR; ZNF329; ZNF180; PIAS1; MGA; NFE2L2; ZNF239; ZNF10; UBE3A; ZNF667; ERCC3; FOXM1; HOXB5; BCL11A; PBX2; ZNF43; ELF2; ILF2; TBL1X; TAF11; ZSCAN18; ARID1A; KLF11; TEAD4; RBFOX2; EHMT2; EHF; SP3; ZNF84; ZNF623; MYCL; NR4A2; E2F8; ZKSCAN4; RNF138; ZIC3; TCF25; ZNF304; SUPT4H1; ZNF571; BCL6; CBFA2T3; ZNF215; ZNF551; FOXF2; HIPK1; TXNIP; KDM4C; ZNF135; IRF6; TOPORS; TRIM22; KAT2B; CDK2; ESR1; PSMD9; TOX3; ZXDC; ZNF529; RREB1; FOXI1; CNOT6; CTBP1; ZNF75D; ZNF33B; INSM1; CTBP2; ZNF83; BNC2; OSR2; STAT4; ZNF263; ZNF136; CAMTA1; CUX2; ZNF611; SETDB1; ZEB1; ZNF711; ZNF394; POU2AF1; HMGB2; DAXX; SOX18; HOXB2; ZNF512B; MAF; ZNF195; GATA6; RSF1; REPIN1; HLF; SALL1; HBP1; TBX2; SOX17; ZNF331; ZNF32; POLR3C; SMARCD3; MXI1; MYB; IRF9; PEG3; GRHL2; CITED2; SIX2; SP140L; ZBTB20; TAL1; SSBP3; SMAD6; KLF4; THAP10; NKX3-1; HOXD1; MED13; TFEC; TFAP2C; TBX3; RYBP; SOX11; HHEX; NFKB2; ID4; NR3C2; MEIS1; VDR; BHLHE41; SMARCA1; ZFP36L1; ZNF91; NR2F1