Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75367	Saracatinib	GSE92742	MCF10A	Human	6h	0.4uM	EID0434

Response Information :

Types	Number	Response transcription factors
Up-regulation	66	MNAT1; RB1; DACH1; ASH2L; TERF1; SMARCB1; CITED1; PIR; NCOA2; EGR4; ENY2; RSF1; SIX1; SAP18; TAF5; SOX17; LOXL2; COPS5; PREB; TAF11; RAD21; CTR9; FOXA2; WWP1; MYT1L; PEX14; BRD8; MYB; SNW1; ZNF721; ID1; TCEA1; ZNF224; ZSCAN16; HMGB3; SND1; ETS2; ZNF587; ASCL1; GATA6; CHD7; ZNF160; TSC22D3; ID3; PTTG1; OSR2; NCOR2; NKX2-1; MSX1; FOXF1; HTATIP2; TWIST1; SAP30; ZNF516; HLF; NCOA6; INSM1; HEY1; NR2F6; KLF9; PITX1; ZNF652; MEIS1; SNAI2; ESR1; HDAC2
Down-regulation	81	ARNT2; TRIB3; BCL6; MTF1; CHD9; RNF10; SMARCA4; KAT6A; ZHX2; FOXC1; KMT2A; ZBED2; ATF1; BAZ2B; PAX6; ZNF423; TBL1X; HIPK3; KDM5D; RUVBL1; MAFB; FOXJ2; GCFC2; ZNF83; NFIB; ZNF512B; PSMD9; IRF6; ZNF544; CCDC59; ZSCAN18; PFDN5; HIPK1; CREB1; NR1H3; BCL3; WWC1; FOXI1; ZMYND8; ZNF140; NR1H4; EP300; PHF20; BACH1; SMAD1; MLXIP; PMS1; GTF2I; PCGF2; KDM5B; FOSL2; TGFB1; RAN; WWTR1; DAXX; GATAD2A; PAX5; MNT; AHR; CNOT2; TOB1; ATF4; ZNF331; TRIM16; TFEB; ELK3; HOXC6; MEOX2; ZEB1; BCL11B; SATB1; SOX9; CREM; MAF; NFKB2; PAX8; ID2; RBPMS; KLF10; E2F2; NFKBIB