Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75366	Saracatinib	GSE92742	MCF10A	Human	6h	2uM	EID0434

Response Information :

Types	Number	Response transcription factors
Up-regulation	120	ZNF586; SSBP2; NFIX; ZNF419; TRIM28; SPIB; FOXF2; IL16; HESX1; SMARCB1; ZNF787; PAX9; CTBP2; MYBL2; CEBPD; ID1; RFX7; ZNF580; ZNF267; ING2; SMAD5; SAP18; SAFB; TP63; CNOT3; MYF6; TGFB1; CHD8; ZIM2; CAPN15; USP21; PPARGC1A; ZNF211; HSF1; HIRA; KLF5; FOXL2; NFIC; IRF6; MXD1; FOXA1; ATOH1; SLC2A4RG; ZNF134; SOX15; ZNF34; FOXO1; ZNF544; PIAS3; BRPF1; TSC22D1; RUNX3; FOXJ2; TCF7L1; E2F2; RNF6; NKX2-2; TDRD3; THAP4; HOXA1; ZNF606; TEAD1; IRF2; TDP2; IRF3; CLOCK; DDIT3; ARL2BP; PTRF; PA2G4; ZNF112; PAX5; CITED1; CBX5; ZNF14; CBFB; CNOT1; MBD2; ZBTB18; FOXM1; ZNF217; SKIL; POLR3C; HMBOX1; FOXE1; SMAD1; SOX9; NFAT5; PITX1; ZNF165; PBX1; JUND; NR0B1; RBL2; CDX1; NFATC1; IRF4; HEY1; BRD4; MED24; NANOG; NR2F6; ZFP36L2; LITAF; AEBP1; NCOA6; ZNF264; ZNF331; WWTR1; TLE4; MEOX2; ZBTB38; NKX3-1; FLNA; NR2F2; IFI16; ID3; PEG3; RUVBL1; PARP1
Down-regulation	103	HMG20B; ARID4B; ADRB2; CHD9; SMAD4; STAT3; ZNF22; STAT5A; ZNF292; SMAD7; MNDA; ATF6; IRF1; FOS; ZFHX4; ZMYND11; PSMD9; ZNF124; TSC22D2; STAT1; BMI1; UBE2B; ZEB2; HMGA2; HDAC2; TRPS1; JUN; INSR; IRF8; CD3D; ATF7IP; SUPT6H; BASP1; HOXB2; AHR; KLF4; MLXIP; PHIP; NR2C1; HMGB3; NFATC4; PNRC1; NR4A2; HLTF; FOSB; ATF3; NPAS2; CHD1; RNF138; TCF21; ETV5; CNOT6; RSF1; BATF3; PLAG1; TCF7; TAF10; HBP1; BRD3; KDM5B; HIPK3; BCL11A; HSF2; SUPT4H1; BTAF1; CRY1; ST18; PSMC3; EDF1; CUX2; TBX2; SHOX2; SMAD2; ETS2; RAN; NLK; DACH1; TCF4; EGR2; DAXX; SOX11; MEIS1; ASCL1; NFE2L3; ARNTL2; HOXB7; ZBTB20; KLF11; ID2; IKZF5; MYCL; NFKB2; PAX8; KLF10; LEF1; MECOM; PBX3; TERF2; INSM1; ESR1; EMX2; BHLHE41; SNAI2