Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75364	Azd-6482	GSE92742	MCF10A	Human	6h	0.08uM	EID0434

Response Information :

Types	Number	Response transcription factors
Up-regulation	98	HOXC6; YAF2; ASH2L; NFIB; NFKBIA; RNF14; NR1H3; LHX6; HIVEP2; HSBP1; RNF6; MYBL2; RBBP7; CTR9; MYT1L; SCAND1; SMAD3; CRK; ZNF266; IL16; MED1; ZNF23; BMI1; HOXA1; SETD2; TOB1; SMARCE1; KMT5A; BRF2; PSPC1; ORC2; NUP62; MEF2A; SP140; CARM1; NFAT5; ZNF432; SIM2; BIRC2; CBFB; TSC22D4; KLF6; HOXA5; RUNX1; HEY1; SMAD5; RUVBL2; PPARGC1A; FOXA2; BRD2; PURA; WWC1; ZHX3; HOXC4; HOXC10; BCL11B; NEDD8; SOX4; ELF1; MAGED1; SPIB; XBP1; CNOT1; IRF5; PTRF; BATF; PIAS2; NCOR2; RNF141; HIPK3; NR2F2; TBPL1; FOXD1; TBP; SMARCD2; ING3; KLF9; TGFB1; TSC22D3; SMARCA2; HMGA1; BAZ1A; CRY1; ELK3; ZBTB38; TSC22D1; CALR; SAP30; EGR3; RHOA; MSX1; NCOA6; PDLIM1; TFDP1; PSMD9; MAFB; RUVBL1; PEG3
Down-regulation	145	ARNT2; ZHX2; ZNF586; ARID5B; ZNF532; TRIB3; TCEA2; PHIP; MYBL1; SOX13; MYCL; ZNF12; PITX2; ZNF500; PBXIP1; PIAS4; SOX12; SOX17; FOXF2; REL; ZNF124; ZNF423; KLF3; KLF1; ZNF512B; NR4A1; ZSCAN9; PNRC1; GTF2IRD1; APEX1; JUN; CALCOCO1; NR1H2; CBX7; HOXD1; ZFP69B; RAD21; CSDE1; SMAD6; SMAD7; HMGB1; TGFB1I1; NFE2L2; ETV5; BCL11A; ZNF669; NFE2L3; ARID1A; MGA; NR4A2; SSX1; BCOR; ERF; ZNF232; TRIM22; NFATC4; NEUROD1; TCF4; SCMH1; MNDA; MEIS2; SSBP3; ZNF180; NR1H4; ZNF304; TBX2; ZNF91; BARX1; ZNF257; ZNF544; ZBED4; E2F5; CIC; CREB1; ZNF239; NKX2-1; IRF9; CNOT6; CREBL2; ID4; HOXD3; IRF7; POLR3C; ZNF195; RSF1; PLAGL1; AHR; AR; ZNF611; PARP1; HDAC2; WT1; HBP1; ERBB4; MBD4; E4F1; SMARCD3; SUPT4H1; THAP10; CCNE1; ZNF93; PRDM1; MEOX2; HOXB2; TFDP2; FOXN3; SOX18; RLF; HLX; ZNF43; TAL1; ZFP36L1; ZNF394; TLE4; NR2F6; HIRA; AEBP1; RBPJ; SHOX2; CUX2; NFKB2; ZNF160; KAT2B; SOX11; ZSCAN31; ZNF652; CTNNB1; ZSCAN18; YBX3; POU2AF1; FOSL2; HIC2; ELF3; EGR2; ZFPM2; ZNF217; FOSB; ZEB1; ZNF430; CUX1; ZZZ3; TOX; ZNF331; MEIS1; E2F2