Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75363	Azd-6482	GSE92742	MCF10A	Human	6h	0.4uM	EID0434

Response Information :

Types	Number	Response transcription factors
Up-regulation	98	STAT3; KAT6A; RFX7; ETS1; EYA2; KDM5D; FOXN3; HOXC6; MEOX1; NEUROD1; BMI1; HOXB6; TSC22D3; MEOX2; MTA2; BRF2; CDK8; CCNE1; STAT2; RORA; TBPL1; CCNT1; XBP1; MYBL1; MDM4; JUP; SMAD1; DLX2; RNF10; HAND1; IRF6; PDLIM1; PQBP1; BBX; SAP18; ELK3; PRKDC; RNF14; FOXD1; MAGED1; ZNF266; MSX1; FLI1; MYCN; BRCA1; HMGB3; E2F2; ZSCAN18; RCOR1; CTR9; HTATIP2; LMCD1; COPS5; TRIP4; IRF5; NFKB2; ZNF131; ASCL1; MKL2; MAF; NR0B1; TSC22D2; HSBP1; GABPB1; TLE4; ZNF32; SIAH2; ZEB2; BHLHE40; BATF; SMARCC1; ZBTB18; INSM1; ZNF217; CENPB; TFCP2L1; RBBP8; SATB1; CTNNB1; TWIST1; SMARCA2; ZNF43; CHD7; PSMC3; PAX5; NFAT5; TOX3; HOXC10; VDR; BCL11B; SOX11; MAFB; TOB1; HDAC2; ZNF165; ZNF91; SNAI2; CDK7
Down-regulation	98	MYC; NFKBIA; ZHX2; BASP1; FOSL1; ID3; THAP11; ZNF532; TRIM22; ID1; RBFOX2; PITX1; CEBPB; CEBPE; SMARCD3; KLF5; GATA6; NR4A1; THRA; ZNF580; PAWR; FOXA2; MNDA; PNRC1; NFE2; CRYM; RLF; ARNT; IRF1; PEX14; DBP; TRIP6; RREB1; YBX1; YBX3; ZNF721; FOXF1; TULP3; SIX1; HIRA; ZNF175; RHOA; CITED2; SALL2; IRF2; WWC1; REPIN1; SOX10; TCF7; DPF2; TGIF1; ZFP36L2; NFATC1; HHEX; HNRNPD; TRIM29; ZEB1; TCF21; CBX4; FOXF2; RUNX1; ZNF611; WNT4; PTTG1; CD3D; TSC22D1; TRIM24; TEAD4; HDGF; HBP1; ZNF652; LYL1; SMAD6; ZNF160; TFAP2C; HLF; HOXD1; BNC2; SPDEF; RARA; KLF2; NKX3-1; VPS72; KLF9; ATN1; TXNIP; AR; BCL11A; DNMT3B; MEIS2; CUX1; ID2; MXI1; TBX3; ZFP36L1; LEF1; DAXX; IFI16