Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75362	Azd-6482	GSE92742	MCF10A	Human	6h	2uM	EID0434

Response Information :

Types	Number	Response transcription factors
Up-regulation	114	FOXO4; EED; MYCN; RUNX3; HOXB7; HOXC6; SKI; ZNF267; TSC22D4; CDK8; NONO; HMGB1; BLM; KDM2A; PNRC1; MAZ; KMT2B; CARM1; CDX2; KDM5B; CTR9; ELK1; ZBTB32; NPAT; DNMT3B; RUVBL2; HLTF; NFE2L1; TCF15; DNAJC1; NPM1; ALX1; NCOA3; MEOX1; HOXA5; HSBP1; HTATIP2; BMI1; MAGED1; RBBP7; TAF10; PIAS2; ZNF302; KAT7; NFIL3; TBPL1; HOXB6; ZEB2; HOXC4; TP53; ZNF189; JARID2; TGFB1; TULP4; BRD3; ZNF574; BTG1; FOXJ3; POU2AF1; TDRD3; ZBTB18; TSC22D3; MLXIPL; IRF5; HEY1; CBX6; NUP62; VPS72; SMAD5; SMAD1; NCOR2; LOXL2; BTAF1; FOXC1; HOXC10; ACTL6A; PIR; MEF2A; CBFB; NKX2-2; IRF4; CNOT1; MXI1; ZFP64; RAN; BAZ2A; BRCA1; CENPB; CHD7; HIC2; SND1; PBX1; IRF8; PAX5; SOX11; TFEC; GABPB1; CRY1; FOXG1; BHLHE41; MSX1; ID4; FLNA; MAFB; TLE4; MAF; BRD4; PUF60; RHOA; SMARCC1; NR2F6; HDAC2; PARP1; CDK7
Down-regulation	77	BCL6; CRYM; ELF5; AFF2; STAT4; ZNF12; TRPS1; ARNT2; TGIF1; EHF; ARID5B; SOX2; SAFB2; PSMD9; NPAS2; TRIB3; FOXF2; PHIP; MYBL1; FUBP1; WWC1; NR4A3; CD3D; JUN; TGFB1I1; NR2C1; JUP; RBBP8; ERBB4; STAT2; IRF6; NR4A2; ETS2; KDM5D; NEUROD1; ZNF512B; MEIS2; ZNF423; HLF; KLF11; NFIC; SOX9; REL; SOX17; PAX6; GATA6; ESR1; ZBED2; ZNF217; TRIM29; FOSL2; HOXD1; DAXX; FOXN3; AR; SP140L; TCEB2; HHEX; RFXANK; PHF20; CBX4; MDM2; SATB2; ETV5; NKX3-1; SALL1; CREM; EDF1; EGR3; ZBTB20; TFAP2C; TBX3; NFKB2; ZIC1; VDR; SNAI2; E2F2