Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75361	Azd-6482	GSE92742	MCF10A	Human	6h	10uM	EID0434

Response Information :

Types	Number	Response transcription factors
Up-regulation	320	STAT5B; HDAC6; PLAGL2; ECD; MNDA; TBP; ADRB2; GATA3; KAT5; MECP2; EP400; VGLL4; PRDM4; KMT2A; HSF2; SSBP2; TADA3; TRIM33; FOXJ1; MNAT1; SKI; TSC22D4; NCOA1; HEY2; BRPF1; EED; FOXO3; NCOA4; PPARG; KAT6A; ARID3B; TSC22D2; PHIP; YBX2; NFYB; HDAC7; ZMIZ1; EHMT1; LMCD1; ZBTB43; CHD1; CTR9; WT1; HOXC13; STAT3; SETD3; TCF15; KDM5B; KLF12; TCFL5; ING2; OSR2; ZNF358; ASH2L; TEAD3; ORC2; CENPB; EVX1; ZMYND11; MAK; ZNF764; RNF138; ANKRD1; SUPT5H; E2F8; TRIM24; ABT1; HIC1; KMT5A; MAX; TAF4; PBX2; NCOA3; TRAF6; ZNF646; CHAF1B; CREB3; ELK1; CHD7; ADNP2; ZNF76; DYRK1B; BACH1; HIC2; GFI1; SMARCB1; BATF; HABP4; CREBZF; TFE3; ASXL1; PHOX2B; ZNF467; AHR; NFIL3; EGR3; PCGF2; RORA; ARHGAP35; ZNF184; NR3C2; TRIM22; SSX1; PEG3; SAP130; UBP1; ZFP30; CCNE1; NR4A1; DNAJC1; TBPL1; TP53; TSHZ2; ZNF3; SPDEF; KLF2; ESRRA; KDM2A; HAND2; MSC; CSDE1; NPM1; NFX1; ZNF629; FOXI1; FOSB; NRL; TEAD1; ZNF165; E2F3; ETV6; HINFP; JUP; SUV39H2; ZNF384; RARA; KDM5C; HMGA1; USP16; ZNF688; BRCA1; XBP1; TULP4; TAF11; ARID3A; PHOX2A; CEBPA; TRIM28; ARID4A; ETS1; ZFHX4; BCL10; FOSL2; PBXIP1; PIAS2; EZH2; NFKB1; VPS72; POLR2A; EHMT2; SMARCD2; NR1D2; TSC22D3; HCFC2; HLTF; PLAGL1; ZSCAN18; ING3; ZBTB18; PAX5; ZNF571; MLXIPL; TFAP2C; ZNF195; ZNF84; HOXD3; CHD3; HIPK1; SOX4; SMARCD3; PURA; GTF2F1; STAT5A; ZNF768; SFMBT1; ZBTB44; MAF; DLX4; POU2F2; TSG101; SLC2A4RG; LIMD1; ZFHX3; ZMIZ2; BCL11B; TRRAP; ZNF443; ZSCAN31; CITED2; ZNF536; HMX1; SSX3; RFX2; ELF4; PPRC1; ZNF669; DBP; RUNX1; JARID2; SOX10; APBB1; SMARCD1; BRIP1; EMX2; ZNF556; ZNF226; TMF1; SNAI1; TOPORS; OVOL2; CDX2; PAWR; ZNF268; SMAD1; ZNF329; FOSL1; HIVEP2; ZNF292; SMAD6; ETS2; IRF5; ZNF227; VDR; EGR2; BTG1; RYBP; ZNF35; GABPB1; NR4A3; BCL3; MLLT10; PROX1; ZNF331; SF1; HOXC6; KLF4; HMG20A; TAF12; ZNF516; MLXIP; TCF7; SMARCA2; MBD2; HOXA4; KLF11; AATF; MMS19; KMT2B; ZNF239; NFIC; ZNF175; HOXC8; HDAC2; RBBP8; CREB3L1; ELF3; CNOT3; CAMTA1; SMAD7; CIC; BAZ1B; EPAS1; ID4; PBRM1; ESRRG; NONO; NR2F2; EP300; TBX2; SETDB1; NOC2L; MYBL1; IRX5; HOXC10; MEN1; NFAT5; SMARCC1; SUZ12; MYCN; DEAF1; HOXC4; POU2AF1; POU4F1; MEIS1; ZEB2; WNT4; HMGB2; SNW1; FOXL2; RCOR3; SOHLH2; SIX3; TWIST1; BMI1; SAP30; SMARCC2; ZNF281; CREM; FOXO1; IRF4; CEBPG; KLF10; MYRF; HLX; NFKBIB; MYB; ZNF32; TCERG1; LEF1; BHLHE41
Down-regulation	293	ARNT2; TCEA2; USP22; MYCBP; HIF1A; NFKBIA; CCNA2; HMGA2; RAD21; FOS; SP110; GON4L; KDM5D; ATF5; GTF3A; CDK2; CERS6; CBFB; YBX1; XRCC6; FHL2; CTBP2; GTF2A2; ZBTB17; IFI16; ZNF423; CTBP1; ENO1; TCEB2; MTF2; IRF3; FOXG1; REXO4; TRIB3; CDYL; ZNF408; WDR77; CUX2; ZNF586; CTCF; ATF6; LHX2; LZTR1; ZNF721; TP63; STAT1; ZNF232; TBX1; FOXF2; MED16; ETV4; CERS4; CRYM; HOXB1; PTTG1; RBM39; MYBBP1A; ZNF215; ZNF557; PREB; MEIS2; ILF2; TOX3; TFDP1; MXI1; IKBKAP; SIN3B; PTRF; ARID4B; ZNF589; C1QBP; MDFI; PITX2; TCF12; ZNF532; CCNH; HDAC9; RNF4; NSD1; SIAH2; ZMYND8; TRPS1; MED13; PMF1; ZNF611; FOXA1; CHD8; TLE1; STAT6; ZBED2; MDM2; IRF6; ZEB1; HOXD10; ATF1; TFAP2A; SCAND1; MTDH; BCL11A; ZNF787; ATF4; RB1; RFXANK; CNBP; ZBTB11; NCOA2; TOB1; ERBB2; BNC1; PPARD; NR1H2; SNAPC4; HBP1; ELK3; SIRT7; THAP11; ARID5B; HOXA10; HOXD11; UBE2L3; ZSCAN32; ZBTB24; SALL1; MYBL2; FOXJ2; ELK4; SATB2; RNF2; SREBF2; SCAI; THRA; PAX9; CREB1; SIX2; BIRC2; TCF7L1; SOX15; NFIB; ZHX2; YBX3; URI1; ZNF652; PBX1; MAFB; ZNF528; HOXB2; ZNF264; TERF1; ID1; CLOCK; JAK2; RNF6; TCF25; NFATC3; DR1; HDGF; RREB1; WWTR1; ZNF22; MED27; ZNF593; ARL2BP; TBL1X; UBE2I; ZNF263; ZFP69B; FUBP1; BACH2; NRIP1; ZNF544; ZNF432; ZNF146; C1D; ETV5; MDM4; PSPC1; HDAC3; USP21; APEX1; INSM1; REST; RING1; TTF1; MAGED1; ZIC3; PKNOX2; IRX4; ZNF160; CRY1; BRD3; BAZ1A; ZZZ3; SP3; BATF3; NFE2L2; CHD9; CNOT1; NEDD8; SIX1; PHF20; PRMT2; TDP2; NCOR1; CTNNB1; RHOA; NFATC4; RNF10; CBX4; INSR; ZNF692; ZNF354A; ABL1; SUB1; GCFC2; SOX11; SPEN; ZFP64; TUB; ZNF675; KAT6B; ZNF131; RXRG; ADNP; MEOX2; BCLAF1; MITF; NFE2L3; CEBPZ; BRD7; ID3; KAT2A; TSC22D1; ZBTB1; PCGF1; MNT; MED17; ZBED1; HMBOX1; BNC2; SERTAD2; ZNF43; FOXE1; HOXA11; NKX2-1; TRIP6; CREB5; ATN1; THAP10; ZNF576; TFCP2; NUP62; HOXB13; ZFP36L2; SOX9; MBD4; HOXB6; PAX6; ZKSCAN1; ZBTB16; TCF21; MYCL; PAXBP1; EN1; CAMTA2; TTF2; SMAD3; TAF9; PRDM1; TBL1XR1; MED24; RBPJ; PMS1; AEBP1; GATA6; BASP1; TOX; HIRA; EDF1; ARNTL2; IRF8; TFEC; FOXF1; ZNF430; PIR; ESR1; HTATIP2; GATA2; ZBTB20; PBX3; BRD4; MEF2C; ID2; E2F2