Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75348	Motesanib	GSE92742	MCF10A	Human	6h	0.08uM	EID0434

Response Information :

Types	Number	Response transcription factors
Up-regulation	102	YY1; MYBL2; SCAND1; NCOR2; CRK; RFX7; CEBPD; SREBF1; TOB1; HEY1; FLNA; KLF5; NFIB; FOXN2; SIX1; FOSL1; TRIM28; TGFB1; KMT2D; KLF7; FOXA2; MYRF; CARM1; MED6; FOXC1; NCOA3; ETV1; FUBP1; SMAD5; PRKDC; CCNC; KMT2B; EHF; RNF4; EPAS1; SOX9; HIPK2; POLR2A; ENO1; TAF10; EGR1; MXD4; TAF9B; TSC22D4; FOXD1; CAPN15; CNOT3; PTRF; NFIL3; HSF1; SOX4; MED15; ID1; CNBP; SUB1; BRD4; MAFG; BATF; RCOR1; NFATC3; ID3; ZNF281; ARNTL; VEZF1; FOXG1; ASCL1; HMGN3; TRIP6; ZNF226; GTF2I; DDIT3; TWIST1; ZNF302; ST18; PAX6; NKX2-2; NR1H3; ELF3; RBL2; CBFB; BMI1; HMGA1; CBX6; CHD7; IRX5; NR2F6; MED1; IRF4; PDLIM1; ZIC1; ZBTB38; PAX5; TFDP1; KLF9; MSX1; INSM1; PSMD9; SNAI2; RUVBL1; MECOM; EMX2; NR2F1
Down-regulation	138	DRAP1; HMGA2; ZNF12; ELF2; MNDA; JUN; PITX2; ARID5B; ATF6; IKBKAP; THAP11; MYBL1; TBL1X; HIVEP1; KLF1; NFE2L3; ZHX2; CD3D; MGA; KAT5; RELA; PBXIP1; ZNF202; STAT1; BASP1; UBE3A; SMAD7; PBX2; CALCOCO1; PHIP; PQBP1; TRIM22; CREBL2; ZSCAN18; FOSB; ZNF274; NCOR1; BCLAF1; KDM5D; ARNT2; FOXI1; SSX1; ZNF512B; GTF2IRD1; BCL11A; WT1; ZBED2; SOX13; HMGB1; CHD9; ZNF304; MED21; TAF7; CDK8; PKNOX2; CNOT6; ZNF710; NFE2L2; REL; THAP10; TGIF1; NR4A2; CBX7; CITED2; CBX5; TLE4; ID4; IRF6; NFYC; ZBED4; TULP3; HOXC10; TGFB1I1; ELF5; COPS2; KLF4; ZNF331; RREB1; GTF2F1; ZNF394; SALL1; JAK2; REPIN1; ZNF93; CNOT2; ZNF350; SMARCC2; RSF1; KAT2B; MYCL; MED13; MEIS2; NR1H4; ZBTB16; ZFPM2; PLAGL1; KLF11; STAT4; TCF4; YAP1; PBX3; ZNF263; PRDM1; DAXX; AR; HIC2; ZNF468; JUP; IRF9; BACH2; ZEB2; DACH1; ATF3; NFKB2; HIRA; RBPJ; TFAP2C; OSR2; ZSCAN31; HOXB13; TFEC; TBX3; BNC2; SATB2; TLE2; LEF1; ZZZ3; ZNF91; ZNF430; CREB3L2; TRIM16; MYB; PIR; ZBTB20; NR3C2; HHEX; PEG3; E2F2