Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75319	Fostamatinib	GSE92742	MCF10A	Human	6h	2uM	EID0433

Response Information :

Types	Number	Response transcription factors
Up-regulation	246	ZMIZ1; ID2; EED; SATB1; PPARG; NR3C2; NFKB2; PLAG1; MDM2; KDM5D; SMARCA1; MECOM; CREB1; SMAD6; ELF3; SOX11; TCFL5; SALL1; TAF12; HMG20A; TCF4; CBX5; HLF; FOXO3; ZNF124; CRYM; PAX8; XBP1; MNDA; PHOX2B; PRMT2; PHIP; ETS2; PCGF2; TRIM32; EYA1; SIAH2; RARB; IKZF1; EGR2; BARX1; HABP4; TERF2; HMGB2; ID1; TXNIP; ZNF253; SP100; CREB3L1; DLX4; KLF15; HMGN3; POU4F1; MBD1; SOX5; HOXD3; IRX5; REL; HMGXB4; AR; BNC2; ZNF287; SCMH1; PRDM1; NR1H4; ZNF33B; TSG101; STAT4; ZBED1; BCL11A; LPIN2; ZSCAN32; PHOX2A; ZNF12; NKRF; HNF1B; HMGA2; CREM; DMTF1; NR1D2; IRF4; PLAGL2; DEAF1; ZNF174; ZNF423; TFEC; TBL1X; ZNF43; MAML1; SERTAD2; MXD3; HOXD1; CREB3L2; RFX5; RARG; PKNOX1; ELF1; PRDM12; SMARCD3; ZNF556; THRA; SATB2; NR4A2; SIX2; HOXC11; SMARCC2; MGA; CBFA2T2; KLF10; ZNF148; TAF11; ZFHX3; PLAGL1; MAF; NCOA1; HSBP1; MEOX1; POU2F1; NFE2L3; MYT1; HLTF; NFYC; BACH1; PAX1; TCF12; ZNF215; DPF2; HIVEP1; RNF10; URI1; ZHX3; TGIF1; ERBB4; HIC2; SUPT7L; MXD1; TAF7; CALCOCO1; ZNF136; FOXA1; GRHL2; CBX6; MED13; TCF20; TCF21; ZBTB20; ZNF415; ZNF239; ETV5; ZNF248; SIX1; MYB; RBBP7; CNOT6; IRF9; HOXD9; HMGB3; CREB5; FOXF2; PRRX2; LYL1; RBFOX2; TCEB2; MYRF; NCOA2; PKNOX2; SSX1; HOXC10; NR4A3; FOSL2; NFE2L2; CUX1; ZBTB38; ZZZ3; PPARGC1A; ACTL6B; IRF7; DNMT3B; YBX1; COPS2; ZNF467; UBE2L3; LHX6; EYA2; NFAT5; ITGB3BP; DBP; EZH1; ABL1; PATZ1; SIM2; TAL1; ZNF117; NFIL3; JUN; PIR; FOXE1; REPIN1; ZSCAN31; ZNF266; HMGA1; FOXF1; SP3; PRDM2; ZNF623; AEBP1; ZNF264; BCL10; HDAC4; RBL2; SSBP3; CBX7; HOXD10; CLOCK; ID4; SPDEF; MED1; SMAD3; ZFP64; PURA; RREB1; NR4A1; DEK; KMT2A; YEATS2; RNF141; BHLHE40; AHR; DLX5; CD3D; CITED2; NKX2-1; ZNF217; ZNF184; CHD3; POU2AF1; ZNF331; NR2F1; MEIS2; TBX3; FOXN3; ZNF160; HHEX; KAT2B; MYBL1; HMG20B
Down-regulation	282	CEBPB; CEBPG; ARID4B; ATF5; JUND; GABPB1; ADRB2; PCGF1; REXO4; NFIB; MEF2D; TMF1; MED27; PTRF; ZNF576; PPRC1; INSR; KMT5A; POLR3F; HSF1; MKL1; NKX3-1; PREB; ATF6; CALR; ZNF410; MTA1; ZNF654; CREB3; TRIM33; LDB1; IRX4; TONSL; BRIP1; VDR; RBM39; BAZ1A; FOXK2; ZNF770; ZNF226; BRCA1; ZNF692; ATF1; PHF2; TBP; SCAND1; ZFX; E2F4; MAFB; ARID5A; TBX2; ZNF165; ZNF593; CCNC; CCNE1; NR1H2; ZNF205; SAFB2; E2F2; SMARCD2; MYBBP1A; GATAD2A; ZNF646; TP53; HDAC9; APEX1; ERF; MSL3; ZBTB48; HCFC2; HOXA10; CNOT3; MSX1; ZHX2; WDR77; NFKBIA; POU3F2; HR; ZNF35; NR2E1; TGFB1; PUF60; SNAPC4; TGFB1I1; HDGF; PMF1; ETV1; MYBL2; ARID3B; MLXIPL; MAK; ZNF219; KDM5C; TRIM29; PAWR; PA2G4; ZNF771; SOX3; ZNF32; ZNF302; HSF2; SRCAP; SOX4; BTF3; ZNF473; HMGXB3; ERCC2; SKIL; KMT2B; MED24; IKBKAP; SETD2; PAX5; ZNF281; CDK9; MED21; KAT2A; DNAJC1; ZNF24; KLF7; ZNF222; ID3; ATF4; DLX2; MYOG; RNF4; TAF4B; NRL; VGLL4; TTF1; NHLH2; RYBP; SMAD4; MAFG; DDIT3; PSMC3; RELB; MAZ; SIN3B; ZNF384; MLX; TCERG1; ZNF83; SMARCB1; NFATC3; NEUROD1; FLNA; ESRRA; SOX15; CCDC59; RBL1; UBE3A; ZNF8; NFE2L1; CTBP1; NELFB; VPS72; BRD2; RBBP8; ZNF211; PIAS2; FOS; TOB1; ASXL1; LITAF; HDAC5; FOSL1; ZNF140; YAF2; ACTL6A; HOXB2; FOXD1; NPAT; CRY1; SREBF1; SOX13; CAPN15; ERBB2; ST18; TGIF2; SMAD5; SPEN; ZNF84; ESR1; ZNF91; PSPC1; NCOR2; ZNF268; HBP1; ZNF432; JUNB; GLI2; GATA3; BRPF1; ZBTB16; NOC2L; AGO2; NUP62; DDX5; NR1I2; ZNF783; CNBP; PSMC3IP; BACH2; CDK8; YEATS4; ZNF227; FHL5; FOSB; KAT6A; SHOX2; HEY1; CHD8; MAFF; STAT1; SRF; ZIC1; SAP18; TOX; ATF3; ZFP36L2; ZBTB7A; BTAF1; ZNF426; ZMYM2; ELF5; BANP; PHF8; AFF4; TAF5; TRIM16; TFAP2C; ZBTB18; ZMIZ2; STAT6; INSM1; TDRD3; PSIP1; HIVEP2; KLF13; CITED1; PPP1R13L; BAZ2B; TSC22D2; NFIC; TRRAP; MED15; SOX9; JUP; YBX3; IRF1; ZNF3; SIRT7; NCOA4; PBX3; TRIM27; NKX2-2; ARNTL; BRD4; WWC1; C1QBP; KLF6; CRK; PAX6; SOX2; RORA; ZNF232; KLF5; SPIB; KLF9; RNF6; ZKSCAN1; TFEB; PITX1; NR2F2; EHF; TRIM22; EMX2; EZH2; CEBPA; BHLHE41; TLE4