Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75310	Mk-2206	GSE92742	MCF10A	Human	6h	10uM	EID0433

Response Information :

Types	Number	Response transcription factors
Up-regulation	144	GATA2; SSBP2; LEF1; TFDP2; MECOM; HOXA3; ID1; ERBB4; RBBP8; SALL1; ID4; EYA1; SIX3; CRYM; PBX2; NCOA1; HDAC5; TGIF1; RBPJ; ZNF467; NR1I3; PRDM14; DLX4; CBX5; SMARCC2; THRA; THAP4; EZH1; GMNN; ZNF354A; TSC22D3; UBE3A; ZNF273; NFKB2; TBX2; LPIN2; ZSCAN32; RRN3; TCF7L1; MDM2; ZNF34; CHD9; MDM4; CUX2; NCOA2; TAF7; TAF12; ZNF512B; HBP1; SOX3; L3MBTL1; LHX6; CIR1; HMGB3; RLF; CDK7; MED12; BPTF; ZNF93; E4F1; SOX11; ZNF107; STAT2; ZNF117; DBP; SOHLH2; MXD1; TFCP2L1; PEX2; BCLAF1; OSR2; SIAH2; MED13; WWP1; RING1; SP3; HMGN3; RXRG; ZFP36L1; NFE2L2; DLX5; SOX17; TRPS1; HIC2; GRHL2; HEY2; TAF9B; ZNF329; ZNF12; BACH1; KAT7; DAXX; NR4A1; PIAS3; ZNF623; SSX1; TCEB2; BTG1; HIRA; ZNF44; CUX1; ESR1; ZSCAN18; YWHAB; CREB3L2; RNF10; ZNF281; HMGA2; MKL2; AR; TRIM22; MED21; ELF3; RNF111; ZNF394; RREB1; RARA; HMGB2; HOXB2; YEATS2; SHOX2; CBFA2T3; KLF10; ZNF239; TCF4; MNT; SMAD3; ZNF665; KDM5D; TCF7; ZNF611; NKX2-1; PNRC1; ZNF430; EYA2; MYCL; NFE2L1; FOXG1; MYBL1; TWIST1; FOXF1; DACH1; ATF3; ZNF331
Down-regulation	144	TFAP2A; JUND; RXRA; SREBF1; ADRB2; TFAM; FOXO3; MED27; TAF9; POLR3F; TCERG1; GATA4; FUBP1; TEAD1; CEBPG; CDK8; CEBPZ; GATA6; RUNX1; SMARCD2; SOX15; MLXIP; WIZ; TGIF2; FOSL1; TERF2; SMAD5; GABPB1; RUVBL2; SAP30; PPRC1; ZNF593; RBL1; ETV4; SIX2; MLX; HMGB1; NUP62; HOXB6; ZNF432; ELK1; NFIB; MYNN; PEG3; WDR77; ELK3; NFKB1; ZNF24; ZNF580; MYBBP1A; ZNF202; ING3; BLM; IRF3; PCGF2; SF1; TTF2; HOXA1; CENPB; NR2E1; ARL2BP; SMARCD3; LOXL2; UBE2L3; UBP1; RBL2; GTF3A; CDYL; PBRM1; EDF1; PMS1; ZBTB20; PTRF; BCL3; NAB1; TRIM32; ETV5; RBM14; PTTG1; NPM1; PAXBP1; BMI1; ZBED2; NKX3-1; PSMC3IP; ZNF146; BRD3; ZNF302; SMAD1; TLE2; ACTL6A; SNAI2; KLF12; ETS1; SUV39H1; NELFB; HOXC10; CTBP2; SMAD7; BBX; HDAC9; BNC2; ZBTB38; ZHX2; ZMYM2; BATF3; DNAJC1; GATAD2A; JUNB; SETD2; STAT3; TRAK1; TGFB1; NFAT5; BIRC2; DLX2; HLTF; KLF2; PBX1; HES1; PDLIM1; TRIM28; ELF4; CBX6; ZBTB18; INSR; TFEB; BASP1; NR2F1; BHLHE41; SMARCA2; EHF; PURA; INSM1; HHEX; HTATIP2; ST18; MED1; TRIP6; RUNX3; SOX9; HOXC6; CEBPA; PPARD