Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75252	Pf-562271	GSE92742	MCF10A	Human	6h	10uM	EID0433

Response Information :

Types	Number	Response transcription factors
Up-regulation	105	TP53; ARID4B; MECOM; TBX2; NFKB2; MAF; PHF1; BHLHE41; EGR1; HOXD1; BCL11A; EYA1; ZNF467; TFDP2; HOXB5; MYCN; ZNF586; TAF12; FOSB; HMGN3; SMARCC2; MED12; SALL1; SOX11; BNC2; PEX2; THRA; HEY2; ZNF32; DACH1; SP100; IRF9; SUMO1; HOXD3; ZFHX3; SP110; PIR; NFE2L2; ERBB4; WNT4; ZSCAN18; ID4; MEIS1; PKNOX2; MYCL; KDM5D; SOX17; SMARCA1; SSBP3; RBFOX2; ZSCAN31; CREBL2; ACTL6A; NFE2L3; TAF9B; OSR2; SP3; FOXF1; HAND1; HSBP1; ZNF136; ZBED2; ZNF264; ATF3; PHIP; ZNF239; ZNF423; CAMTA1; ASCL1; STAT1; ZEB1; FOS; HOXB2; SOX13; PAX8; CREM; TRIM29; ZNF91; MXI1; IRF6; THAP10; TRIM22; SHOX2; MEIS2; ESR1; WT1; HLF; KAT2B; BBX; NR1H2; ZFPM2; CD3D; PSIP1; IRF1; ZBTB18; SOX2; TBL1X; TLE4; TRPS1; ST18; TOX3; ZIC1; BASP1; IFI16; FOXN3
Down-regulation	165	MYC; CEBPB; XBP1; FOSL1; ADRB2; CEBPZ; FOXO3; SUV39H1; EED; IRX4; MDFI; ADNP; RUNX1; SAP30; NUP62; AGO2; TBP; CCNA2; PUF60; PHF20; FOXO1; VGLL4; RXRA; USP22; TLE1; CDK7; TAF4; POU5F1B; REXO4; PDLIM1; TBL1XR1; GATAD2A; PLAGL2; SF1; FOXA1; SOX4; NCOA3; ZNF574; ZBTB7A; ZMYM2; SREBF1; KDM5B; TMF1; BANP; CEBPD; NKX3-1; TFCP2; TEAD1; ZBED4; LIMD1; FOXK2; RBM14; ZNF629; DNAJC2; NFYA; PPARG; SCAND1; TRIM27; MLXIPL; ERCC2; NR2F6; ZFP36L2; MTF2; DDX54; RCOR1; ATF1; PIAS2; TSC22D4; BLM; ABL1; BRD3; KLF9; SMAD5; PATZ1; ARNTL; TFAM; KDM2A; HOXA10; SAFB2; JUND; PPRC1; PA2G4; RREB1; ZNF131; ZBTB16; ZNF302; KLF2; NRBF2; CBFB; ELF1; CTR9; DDIT3; NELFB; SMAD3; ZBTB24; TGIF1; ANKRD1; PCGF2; BRCA1; NCOR2; TAF5; ZFP64; PIAS3; MGA; BTG1; ARID4A; DDX5; DNMT3B; ZNF432; MED7; SFPQ; PAWR; HMGB2; FOXD1; KLF7; CTBP2; E2F3; PAX5; KLF10; TFAP2C; AATF; PAXBP1; CAPN15; PPP1R13L; BRD8; NFIB; BRPF1; POU2AF1; MAGED1; POLR2A; FHL2; INSR; HOXA5; HMGB3; CBX6; HOXC6; MED1; NCOA6; KAT6B; ERBB2; TRIP6; KMT2B; MNT; STAT6; JARID2; AFF1; MAFG; YBX3; VEZF1; FOSL2; TOB1; NLK; CITED2; ERG; RUNX3; NFE2; CREB1; ZNF189; SIX2; KLF5; ZNF721; HMBOX1; CEBPA; NR2F1; CRK