Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75239	Osi-027	GSE92742	MCF10A	Human	6h	0.08uM	EID0433

Response Information :

Types	Number	Response transcription factors
Up-regulation	137	SATB1; NFKB2; EGR2; TCF25; PAX8; HOXC10; EYA1; DAXX; TAF12; ELF3; SOX11; TRIP4; HOXB2; MDM2; MNDA; SCMH1; KDM5B; SMARCA1; HOXC4; RBPJ; ZNF33B; PFDN5; IKZF1; GATA2; ZFP36L1; RARG; ZNF253; REPIN1; MAML1; SALL1; ZSCAN31; BCL11A; NFKB1; PRPF6; DPF2; HEY2; HMGA2; HMGN3; SMARCC2; ELK3; COPS2; HOXC6; STAT4; ZHX2; HOXA1; TBL1X; PHIP; DLX4; ID4; SIAH2; PLAG1; IRF4; CBX5; ZFHX3; TCF4; BHLHE41; CHD9; REL; PEG3; RING1; SIX2; SERTAD2; NFE2L3; MAF; EGR3; RXRG; ZZZ3; CUX1; NR1H4; CREB3L2; E2F6; HOXA11; JUN; HDAC1; LZTS1; SOX10; BNC2; YEATS2; NFKBIB; CLOCK; HMG20A; ITGB3BP; ETV5; AR; MEF2A; HOXA5; NFE2L2; CREM; ZNF239; CITED1; CREB5; GATA6; TULP4; TCEB2; BACH1; HOXD3; GRHL2; ESR1; IRF6; MYCL; PURA; GTF2IRD1; TRIM27; ZEB2; TXNIP; CBFA2T3; TRPS1; HSBP1; CBX6; MGA; CTBP2; RNF111; NR2F2; SP3; NPM1; EYA2; MYB; CREB3L1; WT1; PLAGL1; BCL6; ELF5; BHLHE40; ERBB2; NR4A2; MYRF; CARHSP1; DACH1; NFIL3; IFI16; MEIS2; HOXB7; RUNX3; EZH2; ZKSCAN1; ATF3; HMG20B
Down-regulation	118	ATF5; PMF1; ID3; PSIP1; TTF2; CEBPG; CCNH; TOX; SREBF1; ATF1; PRKDC; FUBP1; RXRA; CDK9; ENY2; NR2E1; CCDC59; HDGF; HCFC2; RNF138; POLR3F; ZNF576; HSF2; MAZ; FLNA; ETS1; MED1; WDR77; IRF3; CRY1; ZBTB11; NFIX; SAFB2; RYBP; KAT2A; SF1; TFAM; NCOR2; ZNF302; ZNF8; CALR; RRN3; TCEA1; KLF7; TFCP2L1; MAX; GFI1B; PPRC1; AGO2; PHF2; SUB1; CAPN15; ACTL6A; MTDH; SAP18; PIAS2; KLF9; HEY1; NFIB; ZNF432; POU3F2; MSX1; ASCL1; TEAD1; NUP62; CEBPD; SAP30; UBE2L3; TP63; NR1H2; SIX6; CNOT3; KDM2A; TBP; NFIC; TGFB1; TWIST1; ZNF532; FOXA2; HIPK1; VPS72; TSC22D2; ID1; FOXG1; SMAD1; KLF5; WDHD1; MLX; PMS1; PDLIM1; NFE2; ZBTB16; BIRC2; E2F3; STAT1; MAFB; BAZ1A; ZIC1; NFE2L1; ZFP36L2; INSR; ZNF528; ARNTL; PPARGC1A; TOB1; BCL11B; KMT2B; PAX6; KDM5D; ZNF224; JUNB; EMX2; ERG; JARID2; ZNF331; ZNF91; SMARCA2; SOX9