Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75209	Gsk-3-inhibitor-ii	GSE92742	MCF10A	Human	6h	2uM	EID0433

Response Information :

Types	Number	Response transcription factors
Up-regulation	341	E2F2; MEF2C; KDM5A; EGR2; ZNF586; ZEB2; NANOG; PPARG; NR3C2; SUV39H1; ADRB2; FLI1; PRDM1; MNAT1; CEBPZ; TXNIP; IFNB1; SOX10; POU5F1B; ZNF589; IRF4; NEUROG1; IRF5; SOX21; NR4A3; PHF20; LIN28A; EBF2; NEUROD2; FEZF2; STAT2; CREM; CBX2; HOXB8; IKZF3; HOXB5; NEUROG2; TULP4; EGR3; PAX3; PAX1; ZBTB7B; VGLL1; NCOA1; MAF; EYA3; MLLT10; SKI; TFDP2; KDM5D; VAX2; WHSC1L1; TBL1Y; HOXB6; TSG101; ZIC1; HOXB13; RFX2; NFE2L3; ZIC3; RFX1; TDP2; THRA; PRDM14; MXD1; ELF5; LZTS1; TOX4; ZNF257; NFKB2; ZNF492; ARNT; CTNNB1; GBX2; ZNF536; ZNF124; ZNF93; TCF7L1; REL; KLF4; MAPK8IP1; ALX4; BNC2; EMX1; LMX1B; CUX2; GTF2IRD1; HABP4; DLX4; ZNF329; TGIF2; CDX4; MAFK; RARG; KLF15; TOX3; PRDM5; HEY2; SOX18; TERF1; PRDM8; ZNF571; ZNF778; FOXI1; SOX3; TBL1X; ATOH1; ZBTB39; MED12; HOXB1; ZNF654; CREBL2; ZBTB44; ATF6B; ZNF148; LHX5; BCL11A; TULP1; ZNF141; TULP2; RNF4; SIX1; PREB; MDM2; RSF1; STAT4; NR1D2; DNMT3B; NEUROG3; FOXP3; GRIP1; SOX12; ATF7IP; CTR9; HNF1B; LHX2; AFF3; ZBTB25; TLX1; ZNF701; NR1I2; ZNF350; ZNF286A; HIPK3; NFIX; ZNF135; MSC; ZNF613; SUPT5H; TFE3; ZNF544; XBP1; AFF2; ZNF573; BATF; ZNF682; DDX17; SMARCA5; PRDM2; PAX8; LHX1; LPIN2; HIC1; ARRB1; ZKSCAN8; SAP130; EP400; POU2F3; FOSB; ZNF667; TAF6L; BASP1; TRIM25; PLAGL1; ECD; GFI1; ASH2L; CBFA2T2; ZNF268; ZNF84; NR3C1; ZNF440; PRDM16; SIX3; ZSCAN18; ZNF529; TBX21; SOX1; UTF1; NCOA2; BARX2; NR2C2; RARB; ZNF408; ZNF248; SP2; TAF1A; TFCP2; KDM5B; DAXX; GON4L; MYOD1; OSR2; HOXC10; GTF2I; ZNF652; ALX1; CRYM; IKZF1; ZNF276; PML; BCOR; SMARCA1; EHMT1; PLAG1; HOXC8; CAPN15; THRAP3; BBX; CHD7; DMRT1; PSMC3; EHMT2; NEUROD1; ZNF362; ZNF33B; MEN1; DEAF1; ZNF202; POU2F1; TBX1; SSBP3; NHLH2; TRIM22; PRMT2; PKNOX2; DACH1; ST18; TFCP2L1; SMAD5; NRBF2; CSDC2; NR4A2; HOXB9; ZNF587; ZNF274; MTF1; TGIF1; HMGB2; MYBL1; EPAS1; MYT1L; GLI3; RUNX3; SOX13; NFATC1; HTATIP2; HDAC4; HOXB2; PIR; SMAD6; SOHLH2; MYCL; ZNF510; HMGA2; IL16; ERBB4; GABPA; POU4F1; CREB3L1; ZFHX4; RELA; REST; ZBTB38; TRIM16; TRRAP; NCOR1; HLX; RREB1; EGR4; ZBTB18; MED21; FOSL2; TSC22D2; RBL2; JAK2; TCF20; SMARCA2; JUN; REPIN1; RAN; SUPT4H1; MYT1; ZBTB16; RARA; NFIL3; ZNF189; PDLIM1; AHR; ZNF669; PBX3; HIVEP1; BHLHE40; ZNF43; ZNF345; SMAD2; SOX11; RBPMS; SMAD7; CDYL; BHLHE41; NFKBIB; SLC2A4RG; BCL11B; FOXO4; NAB1; FOXE1; EYA1; KDM2A; ZNF528; TFEB; KMT2B; SMARCA4; CBX7; SP3; CBFA2T3; NR2F1; HSBP1; ELF3; ZNF665; MAFF; ZNF552; FOXN3; TRIP6; EN1; CTBP2; EZH2; HDAC2; ZFPM2; HMG20B; CRK
Down-regulation	388	CEBPB; CDK7; DRAP1; RNF138; PARP1; IKBKAP; DNMT1; ATF5; ZMIZ1; GTF2A2; CBFB; TAF1D; SCAND1; YBX3; MTF2; ARL2BP; RBM39; ABL1; ID1; ID3; RBBP8; SND1; RBBP7; RYBP; BAZ1A; FOXJ3; HMGB1; RFX5; GTF3A; UBE3A; ZNF593; ZNF83; ETV4; RFXANK; HDAC7; DR1; FUBP1; APEX1; CEBPE; HMGXB3; ZBTB17; ACTL6A; VGLL4; ZNF562; SP110; YEATS4; HDGF; POLR3F; E2F4; HES1; GMEB2; MEIS1; SUB1; ELK3; PHF2; SRCAP; MED27; THAP7; PCGF1; PITX1; RUNX1; VDR; ZNF468; STAT6; BIRC2; UIMC1; MYNN; NRIP1; CEBPD; SAFB; KAT2A; ZNF12; HMX1; NFE2L2; UBP1; WDR77; IRF3; SNAI2; MTA1; ZNF232; UBE2B; ZNF446; SAFB2; SCMH1; PRDM10; TSHZ2; MEF2D; ZNF410; TAF5L; CNOT1; ZBTB7A; FOXJ2; HOXA4; MXD4; TAF10; CNOT6; CARM1; ZNF226; MED23; TRIP4; THAP1; JUP; MYBBP1A; ERF; CCDC59; TMF1; MXD3; TCEA1; CIC; GATA6; CBX4; ZNF24; MSL3; ZNF672; INSR; C1D; SF1; ZMYND8; AES; WIZ; CAMTA2; PRKDC; ELF1; MED15; KLF7; ZNF354A; CERS4; KDM5C; PAX5; TBX2; RRN3; ZFP36L1; PMF1; RCOR1; DNAJC1; BCLAF1; HR; YAP1; USP21; NR0B2; TP63; ZNF324; ZSCAN5A; SMARCB1; RNF6; TTF1; NKX3-1; PAWR; WWP1; ZNF219; PIAS1; ZNF131; MED17; MED25; FLNA; CALR; MSX1; HOXA10; TCF3; CRY1; BTAF1; CCNT1; SIN3B; HOXA7; SSBP2; UBTF; HDAC3; NR2F2; NR1H4; BRF2; MECOM; ZNF263; ZNF580; WWC1; PA2G4; TERF2; HOXD11; ZNF212; ZFX; HIPK1; LDB1; ESRRG; ZNF646; CSDE1; MAZ; GATA2; ZBTB48; CDK9; STAT1; KLF1; HOXA5; ZNF8; ZBTB1; ZNF32; MLXIP; TRIM33; TGFB1I1; SMAD3; SAP18; ASCL1; WWTR1; SMARCD1; RCOR3; TTF2; TCF7L2; ADNP2; PTRF; ZSCAN12; ARID1A; TCF21; C1QBP; MED24; ZNF195; PCGF3; ERBB2; TFAP4; THAP10; TRIM32; MTDH; BCL3; NOC2L; SPI1; BNC1; KLF2; CBX8; SPEN; KAT6B; NKRF; ZBTB11; RUVBL2; TSC22D1; ZNF532; TOX; CUX1; ZNF44; FOXL2; PIAS3; CDK8; RNF10; HEY1; CIZ1; HMGA1; RBL1; ZNF107; SHOX2; UBE2L3; ARNTL2; MLXIPL; ISL1; JUNB; HSF2; PBX2; REXO4; ESRRA; CXXC1; HHEX; ERG; ELF4; CNOT2; ZNF23; HOXD13; CREB3; HSF1; THAP4; RERE; CALCOCO1; CREB1; HMGXB4; RNF14; FOXD1; POLR2A; ZNF512B; CREB5; ELK4; ZFP36L2; ZNF302; CHD4; SMAD4; TADA3; HOXD1; SOX9; NCOA6; CHD9; E2F6; CEBPG; ZBTB40; POU2AF1; AR; USP16; ZNF629; JUND; BLZF1; TBL1XR1; MED1; MAFB; ZFP64; CCNE1; AIP; RFC1; ANKRD1; PKNOX1; SREBF1; TRIM27; SIX6; BATF3; PSMC3IP; HDAC9; SUPT3H; ZNF516; ZNF783; LYL1; ZBED4; CREB3L2; IRF6; AEBP1; OVOL2; CBX6; TOPORS; MITF; WDHD1; SIX2; TAF5; E2F8; ZNF3; POU3F2; BAZ1B; TCF15; TRAK1; NR4A1; HLTF; MED13; SUPT6H; BRD8; ZNF266; SIRT7; DLX2; ZNF281; TCF7; RBFOX2; SIAH2; LEF1; DDIT3; TCF4; TSC22D4; KLF10; PAXBP1; TCF12; CHD8; MEF2A; ZBED2; MEIS2; KLF5; CITED2; ZNF222; CARHSP1; TRIM28; NKX2-2; FOXF2; BRD3; MBD2; BTG1; ZEB1; SMAD1; BRD4; ZNF91; VEZF1; BCL6; BAZ2B; CAMTA1; ATF3; MNT; CHD3; WT1; NFE2; KMT2A; TLE4; MAFG; BRPF1; NCOA4; KLF6; PRRX1; JARID2; INSM1; HMBOX1; HOXC6; ESR1; IFI16; VPS72