Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75197	Hg-5-88-01	GSE92742	MCF10A	Human	6h	10uM	EID0433

Response Information :

Types	Number	Response transcription factors
Up-regulation	402	IKZF1; NANOG; RELB; NEUROD1; ZNF492; EGR2; ZNF586; POU5F1B; MYT1L; SATB1; HOXC10; EGR3; ZNF93; TXNIP; SALL1; KLF4; ZIC1; HOXC13; ZNF589; TFDP2; MYCN; ZNF124; LZTS1; ZNF257; PLAG1; TBL1X; VAX2; ZNF33B; BNC2; PAX1; POU6F1; SOHLH2; HMGXB4; ZSCAN18; GON4L; ZNF253; EP300; ZNF135; NFKB2; ZNF682; ZNF671; ID4; SSBP3; NHLH2; SALL2; KDM5D; ZNF208; NHLH1; ID2; NEUROG1; ZNF701; HOXB2; CSDC2; BRIP1; BRWD1; ZKSCAN7; ZNF329; ZFP30; GCM1; KAT7; ZNF440; STAT4; FOSB; ZNF304; PGR; POU2F1; STAT2; SMAD6; TRRAP; ZNF154; CREBL2; ALX1; TULP4; SOX21; TAF4B; EN2; ZNF813; ZNF14; PLAGL1; NR2C1; ZNF264; SOX11; ZNF606; ZNF536; PFDN5; ZKSCAN8; POU4F2; ZNF217; PAX8; TFEC; PRDM1; SMARCD3; ZNF654; KAT6B; KAT5; FOSL2; SHOX; RFX3; TCFL5; ZIC3; DNMT3B; ARID4A; MED12; FOXD1; TEAD3; ZNF180; LHX2; ZNF175; SREBF2; GLI1; MSC; ATOH1; HNF1B; BARX2; ZNF443; TP53; ZSCAN31; IKZF4; ZBTB7B; OSR2; ATF7IP; NEUROD2; TBL1Y; CITED2; SP2; WT1; ST18; LIN28A; PEG3; ZNF415; IRF4; REL; ZNF665; ZBTB18; MXD1; ZNF506; IKZF3; FOXP3; ZIM2; MZF1; CREB3L1; DLX4; MAML1; RARG; ZNF778; ZNF695; AFF2; NR4A2; PEX2; GBX1; NCOA1; IRX5; SIAH2; ZBED1; ZNF544; STAT5A; CREM; TFCP2; ZNF148; CDIP1; SKI; ZBTB7C; MYB; TLX1; ZNF688; ZNF571; ZBTB6; ZNF141; ZNF211; ZNF419; TBX21; TEF; MED7; PRDM5; HOXC6; LHX1; ZNF35; ZNF331; EBF2; EYA1; ZFY; KMT2D; ZNF335; TAF9B; ZNF226; ZNF239; TOX4; EYA3; PRDM13; DAXX; PITX2; ZNF287; MAK; CBX2; SOX13; EZH1; MAPK8IP1; THAP11; TBX1; ZNF132; ZBTB43; CHD2; TGFB1I1; EMX2; HLTF; STAT5B; SUPT7L; TSC22D3; PRMT2; MED23; MAFK; KDM4C; ERBB4; HNF4G; HBP1; ZKSCAN4; NAB2; OVOL1; SUMO1; IRF5; BRDT; ZNF225; BARX1; KDM4A; ARNT; E2F5; HOXB13; GTF2I; ZBTB44; MAP3K10; CBFA2T3; MEOX1; TAF6L; MYOD1; KDM5A; CUX1; HOXC8; TSG101; NFE2L3; RBBP4; KLF2; FOXA1; TCF25; ZBTB14; UTF1; CBX7; CENPB; INSM1; NCOA2; BCOR; HEY2; NFAT5; ESR1; TERF1; TRIP11; CD3D; ZNF529; ZFP37; CDK8; ZNF136; ZNF268; NFYC; FOXI1; GTF2IRD1; NPAS2; TAF9; BACH1; RORC; HSF4; EGR4; MYCL; NR4A3; CHD8; TADA2A; SCMH1; HMG20A; HDAC4; SETDB1; CTNNB1; ZNF711; ARRB1; RBPMS; IRF9; TRIM25; ZNF134; TRIP6; TFE3; HIPK1; DLX5; KDM5B; FOXE1; RSF1; TAF12; RBL2; TLE2; ZNF573; NR2F1; NPAT; ZNF345; SNAI1; FLI1; MYRF; BMI1; HOXD9; TRIM16; THRA; ZNF266; ZMYND11; NR2C2; PNRC1; ZNF227; BHLHE41; HINFP; NONO; PIAS3; BCL10; ZNF430; FOXO4; ACTL6B; ZNF611; COPS2; ZNF3; KLF12; AR; ZNF562; CNOT3; BRD3; NFKBIB; CIITA; VGLL1; BCL11B; ZNF85; ZNF140; ZEB2; NFIL3; HOXB7; ZNF652; DBP; PBX1; ZNF623; CITED1; ZNF222; DDX17; MEOX2; IRF8; ZNF189; GLI3; DEAF1; ZNF426; ZNF177; ZNF112; BASP1; JAK2; NR5A2; ZZZ3; TFAP2C; PAX6; SIM2; ZNF224; HOXC4; CARHSP1; ZNF835; STAT3; TLE4; SIX2; MBD4; PRDM2; FOXJ1; HOXB6; SOX2; HMGA2; ZKSCAN1; NFATC1; HMBOX1; BCL11A; PHIP; HSBP1; KLF9; HTATIP2; YEATS2; PIR; CBX6; MITF; ING2; ELF3; SMARCA2; MEIS2; CDK2; BTG1; TRPS1; ZNF423; RUNX3; DACH1; ZNF160; AHR; MYBL1; FOS; SMAD2; ZBTB38; FOXN3; HMG20B; CEBPA
Down-regulation	340	MYC; GMNN; CEBPB; DRAP1; ZMIZ1; TFDP1; ATF5; IKBKAP; CBFB; SCAND1; ABL1; CEBPZ; RBM39; SF1; ELK3; CDK9; ID3; CREG1; RFX5; FOXJ3; HDGF; IRF3; MTF2; ZNF593; RYBP; ZFP36L2; ELF1; CEBPD; CALR; VGLL4; MDFI; CREB3; ZNF692; TLE1; SOX15; PRDM4; KAT2A; RUVBL2; GTF3A; PA2G4; NKRF; TAF1D; CNOT2; TFAP2A; JUP; PLAGL2; CCDC59; MED27; PITX1; FOXO1; UBP1; WDR77; MED25; ZBED4; UIMC1; ETS2; DR1; DNAJC2; E2F4; LOXL2; STAT6; FUBP1; POU2AF1; TAF10; BAZ1A; FLNA; FOXK2; SUB1; PTTG1; CEBPE; MECOM; YEATS4; NFE2L2; FOXJ2; MNAT1; BRF2; ZNF195; YBX3; MTA1; HSF1; HMGA1; MTDH; SND1; TP63; LDB1; TAF4; MBD2; HNRNPD; ID1; MYBBP1A; HES1; PUF60; SP100; WWTR1; SP110; HOXA4; BAZ2A; ZFX; HCFC2; PPRC1; ZBTB17; RUNX1; KAT8; SAFB; RBBP7; HMGB1; ABT1; TMF1; WWC1; TFAM; RCOR1; ZNF205; ZMYM2; ADRB2; RNF138; CDC5L; CERS4; SETD2; PAX5; SRF; BCLAF1; RNF4; ZNF672; TRIM33; PSMC3; MED15; ZNF771; HIF3A; GMEB2; BIRC2; ZSCAN2; ZSCAN12; CDYL; REPIN1; VSX1; POLR3F; EDF1; ZNF281; IRF6; PPP1R13L; RNF6; IRX4; CBX4; BRD7; NR0B2; FOSL1; HOXA7; ZNF131; RFXANK; PHF20; SAP30; LMO1; PHF2; TERF2; TRIM27; SAFB2; SPI1; BPTF; TSC22D1; ZNF384; LMCD1; DEK; ZNF219; UBE2I; CCNC; KLF5; DDIT3; TSHZ2; CIC; RRN3; NCOA6; KMT5A; ZNF580; ZBTB16; MED1; ASCL1; SRCAP; TTF1; RBBP8; CLOCK; YAF2; PMF1; MED6; REXO4; USF2; MYBL2; ASXL1; PCGF3; POLR2A; SMARCB1; NFYA; ARL2BP; ZMYND8; FOXF2; NCOR2; BNC1; ERBB2; TFEB; KLF7; MLX; SMAD3; CHD4; MSX1; PAXBP1; MYOG; MAFB; MLXIP; TAF11; BANP; ATN1; ERF; CTBP2; GFI1B; XRCC6; SUPT4H1; DPF2; KLF1; ZNF532; ZNF446; HIPK2; SMAD4; AEBP1; CREB3L2; MXD3; CERS6; SOX9; ZBTB20; SMAD1; RXRA; SFPQ; ZNF107; SIRT2; RBM14; TDRD3; C1QBP; HOXA10; ZNF24; TOPORS; ARNTL; ERG; LEF1; NFIB; NUP62; PDLIM1; PHOX2B; MAGED1; HOXB3; HHEX; DNAJC1; MLXIPL; KAT2B; ELF4; PMS1; CBX3; CEBPG; ISL1; HCFC1; LYL1; CDX1; TCF21; TCEB2; RFC1; ZNF12; FOXM1; CRY1; GATA6; SNW1; PIAS2; HOXA5; ARID5B; ARNTL2; TCF12; AFF1; MYCBP; TCF4; NFKB1; PROX1; TGIF1; CREB1; CARM1; NOC2L; BCL3; IFI16; SAP130; POU3F2; CNBP; ZFP36L1; BRCA2; RNF10; BCL6; CTBP1; APEX1; SERTAD2; ZNF232; PPARGC1A; ZMIZ2; SPEN; FOXA2; ANKRD1; STAT1; BRD8; NFE2; BLM; JUN; SIRT7; MED13; NKX3-1; ZBED2; ZNF516; DDX5; KLF10; NR4A1; KMT2B; TOX; CENPF; CHD9; TCF7; CBX5; BTAF1; NFATC3; SMARCE1; VEZF1; GATAD2A; KLF6; COPS5; E2F3; SNAI2; IKZF5; INSR; SUPT3H; TGFB1; AES; WWP1; BRPF1; HEY1; JUNB; SHOX2; MAFG; PBX3; NR2F2