Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75189	Gw-843682x	GSE92742	MCF10A	Human	6h	10uM	EID0433

Response Information :

Types	Number	Response transcription factors
Up-regulation	115	ZEB2; PLAG1; TP53; NPAS2; IRF4; IKZF1; STAT5A; GATA6; KLF2; PITX1; ZKSCAN7; HOXD3; EWSR1; MED16; MEOX2; PLAGL2; KLF7; SREBF1; ENY2; NFIC; HCFC2; BCL11B; ZNF783; STAT4; E2F5; TBL1X; ZNF473; ZNF587; LEF1; HMGXB4; BCLAF1; REST; MDM2; LMCD1; NFYA; ZNF274; ZNF468; SMAD4; SIAH2; SMAD6; KLF10; CCNE1; ZNF423; NUP62; RBBP7; ZNF408; BBX; TGIF1; ZNF711; HLTF; ZNF266; NRF1; CTNNB1; ATF7IP; GTF2IRD1; SMAD7; USP16; TXNIP; POU2AF1; ZNF415; SMARCA1; ZFHX4; OSR2; CRY1; RREB1; NCOA4; ISL1; EZH1; TCF21; ASXL1; PPP1R13L; WWTR1; HIPK3; BACH1; SOX11; ZMYND11; PIR; E2F6; ZSCAN18; MYRF; CBX3; MBD4; CHD3; JUP; HOXB2; CREB3L1; ERBB2; TRIM28; CREB3L2; NFAT5; AATF; CREM; GTF2I; SFPQ; JARID2; AHR; ZBTB38; TCF7; ZNF160; ZBTB18; TRIM29; PEG3; ZNF721; SMAD2; SUB1; CD3D; PBX1; HOXA5; RORA; HTATIP2; RBPMS; RUNX3; PBX3; MEIS2; CRK
Down-regulation	128	PARP1; MTF2; VGLL4; TRIB3; FUBP1; ATN1; ZNF557; PFDN5; ZNF354A; ZNF205; DEAF1; HOXA10; TAF11; FOXM1; ZNF768; CHD4; HEY1; CNOT3; NR1H4; SP110; KMT5A; ATF6; IRX4; ERF; YBX3; ZNF12; HOXC10; DR1; THRAP3; PHF1; FOXJ2; CREBZF; SPI1; RBPJ; ATF3; PBX2; ZFHX3; TDP2; SALL1; BAZ2A; BRD7; LOXL2; MAX; ZNF580; KLF9; TADA3; ARL2BP; TCF4; FOXL2; WDR77; RBBP8; DACH1; NR4A1; KLF4; FOXN3; SIX6; CREB3; ZNF589; FOXA1; TOX; MAZ; VDR; ZNF133; NFX1; ZNF165; NFE2L3; IRF2; ARID5A; CBFB; SUPT4H1; TAL1; CREB5; NAB2; FOXG1; SHOX2; IRF6; CALR; RERE; NFE2; SRF; EPAS1; VEZF1; HLF; ZNF281; ELK4; BCL11A; TSC22D1; PNRC1; DLX5; TULP3; ETS2; TCF3; TFAP2C; LITAF; MAFF; GATAD2A; MXI1; BRD3; JUN; ID1; ZIC1; HIRA; SLC2A4RG; COPS2; IRF7; TWIST1; DLX2; DEK; NFATC4; MSX1; IFI16; TOX3; MKL2; CTBP2; ELF5; ESR1; EHF; ERG; CRYM; BHLHE41; ZNF91; EMX2; TOB1; VPS72; INSM1; ZKSCAN1; NR2F2; CEBPA