Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75167	Bi-2536	GSE92742	MCF10A	Human	6h	2uM	EID0433

Response Information :

Types	Number	Response transcription factors
Up-regulation	462	EGR2; IKZF1; MEF2C; NR0B1; NR3C1; GATA2; RELB; TFDP2; PPARG; MNAT1; CHD7; ZNF701; SSBP2; KDM5A; EP400; ZEB2; ZNF329; IRF4; ZNF93; SATB1; NR1I2; NCOA1; ZKSCAN7; SOX21; NFAT5; SSX1; WHSC1L1; ID4; NR3C2; NEUROD1; LMCD1; EPAS1; GATA3; ZNF671; GATA1; ADRB2; ZBTB39; PAX7; PLAGL2; MEOX2; LHX6; ZBTB44; ASCL3; NEUROD2; ZIM2; CDX1; ZSCAN16; ZNF253; GON4L; IKZF3; NANOG; PIAS2; TBX21; HNF1B; DLX4; HEY2; ZNF165; BRWD1; STAT2; EGR4; GFI1; HCFC2; POU6F1; CBFA2T3; CTNNB1; ZNF587; RBBP5; TAF4; BHLHE41; HABP4; RFX2; PRDM14; HESX1; CREBZF; LEF1; FOXJ3; SERTAD2; MED31; FEV; ZNF507; LPIN2; TULP4; NR5A1; NR1I3; DNMT3B; ZNF223; CBX2; LIMD1; MAF; POU2F2; CHD2; TAF1; MECP2; KLF13; HEYL; HOXA1; OVOL1; MLLT1; TRIP11; SMAD7; SP4; PRMT2; ZNF141; ZBTB16; PHOX2B; MAPK8IP1; GATA6; IFNB1; ZNF589; CDX2; KLF2; ZNF276; NFATC3; EYA3; PRDM5; PROP1; ZNF506; ASCL1; L3MBTL1; STAT5A; ZNF75D; SSX3; HOXC5; FOXD3; ZNF343; ARNT; E2F5; RSF1; ERG; ASCL2; FHL5; HIVEP2; SAP130; HDAC9; SMAD6; ID2; ZBTB14; EGR3; CSDC2; CIC; MED12; ZNF771; ZIC3; HOXA2; TAF7; MYCN; TBX2; ANKRD1; ZBTB6; EBF2; EZH1; REL; FOXO1; TAF4B; NFRKB; MBD1; SHOX; AGO2; DACH1; MYB; PAX1; ZNF492; GCM1; PRDM2; EMX1; KMT2A; KLF9; RARG; VGLL1; NHLH1; ZNF778; ZNF571; ZMIZ2; BARX2; CREB5; SMARCA1; TWIST1; ELF3; ZSCAN32; TFCP2L1; ASH1L; HDAC11; ZNF154; SALL2; MYT1L; NR6A1; NRBF2; SKI; ZNF235; NR1D2; NPAT; PRDM8; TERF2; STAT4; ZBTB3; KLF15; CREM; PRDM10; ZSCAN9; POU4F2; MED7; ARID3B; POU3F1; KDM4A; MTF2; YBX2; BBX; CRTC1; SUV39H2; HCFC1; SOX17; HAND1; E2F1; MYBL2; SP140; ZNF236; FOXB1; CAMTA2; NR1H4; ZNF721; MYOG; DDIT3; ARID3A; ZNF682; ATOH1; XBP1; DMRT1; BCL10; MAFG; GBX1; BNC1; ZNF358; LHX3; NKX2-2; HOXB9; TRIM24; KLF4; ZBTB25; TLE2; EYA1; YAF2; TFAP2B; ZHX3; NEUROD6; SOHLH2; FOXD2; ZNF665; ZNF573; ZNF222; ALX1; FOSB; ZBTB38; LMX1B; CBX7; EVX1; ING2; ELK1; HNF4G; ZSCAN18; ZBTB43; NRL; IRF6; TAF9B; CBX5; EED; ZNF254; RFX7; WWP1; ERBB4; ZNF552; FOXH1; SNIP1; KMT2D; RUNX3; MBD2; CCNE1; ZNF160; MAP3K10; ZNF227; BLM; ZIC1; EHMT1; IRF2; ARNTL; TRIM25; TCF7; DDX5; ZNF443; ATF7IP; TSHZ2; SKIL; KLF6; SMAD5; TP53; IRX5; IL16; PDLIM1; ZNF107; ZNF177; IRF5; BCL11B; KLF10; AFF4; TSC22D2; CALCOCO1; KLF3; ZBTB18; KDM5D; AFF2; SFMBT1; CCNT1; TCF4; E2F3; URI1; SOX10; FOXO3; ESR1; NFYB; HDAC6; ZNF423; ZNF654; EGR1; HIVEP3; ZFPM2; ZNF257; ZNF432; MECOM; SMARCD2; ADNP; HOXD3; ZNF695; RLF; ZNF286A; TSG101; MLLT10; ETV1; POU2AF1; ZNF493; ZNF415; TFEB; TEAD1; POLR2A; ZNF611; DMTF1; NPAS2; TBX3; CERS6; ZNF124; TLX1; ECD; MTA2; PHF20; ZNF281; VDR; PHOX2A; NFKBIB; ZNF510; SMAD3; KDM2A; PPP1R13L; POU2F1; TBL1XR1; SNAI1; INSR; WT1; TAF1A; HIPK2; SIX3; KAT7; HMBOX1; MXD1; CRYM; FOXN3; DDX17; ASH2L; SUPT7L; NFIB; PBX2; TRIM22; MED13; FOXE1; ZBTB20; SAP30; ZNF274; SP1; ZNF202; CD3D; TCF7L1; ZNF112; CXXC1; MAX; MYBL1; ING4; MLXIP; THRA; ID1; CEBPD; RORA; PPARGC1A; PIAS3; BPTF; BTG1; PAX8; PITX2; RNF111; YEATS2; SATB2; ZFHX4; LIN28A; KAT6B; MAGED1; IRF9; SMAD2; NR2C2; ZNF195; NFKB2; TSC22D4; ZNF117; BRPF1; ELK3; SAFB; KLF12; RBBP4; MBD4; HTATIP2; ETS2; ZNF345; NAB1; SETD3; HOXC6; PAX5; NONO; IRF8; NFATC1; NLK; ZNF85; ZNF430; DBP; FOXJ1; ZNF140; NKX2-1; PURA; ZNF91; RARA; CBX6; NR4A1; HMGB3; NFE2; TBPL1; NFIL3; OLIG2; EMX2; BHLHE40; FOXG1; HOXA5; EZH2; NR4A2; AHR; ZNF331; ARID5B; SMARCA2; CRK
Down-regulation	454	PUF60; PCBD1; ARID4B; CEBPB; RNF138; DRAP1; PCGF1; MYC; MTDH; IKBKAP; PARP1; XRCC6; TCERG1; TFDP1; PMF1; RUVBL1; NR2F6; DNMT1; NFKBIA; DNAJC2; ZNF593; ZFP36L1; PSMD9; ATF5; RBPJ; HDAC1; ERCC3; GTF2A2; CDK9; SSRP1; YBX3; RNF4; HDGF; JUP; KAT8; TLE1; PQBP1; IRF3; TCF25; CCNH; ARNTL2; FOSL1; UBE2L3; RFXANK; ATN1; THAP4; ZNF12; ZBTB11; ENO1; CCDC59; MDFI; MED17; ATF2; WWTR1; BCLAF1; ETV4; NKX3-1; ARL2BP; ZBTB17; DR1; SP140L; WDR77; CALR; FLNA; KAT6A; CBX4; REXO4; ATF4; IRX4; MEF2D; CENPB; CSDE1; NELFB; SCAND1; NOC2L; RFX5; ZBED4; ZNF7; MED16; SOX15; SP110; HSF1; ZNF692; LOXL2; RBM39; TEAD4; DPF2; RYBP; RB1; THAP7; HMGXB4; KDM5B; COPS5; CNBP; SUMO1; HBP1; MAZ; SRCAP; BAZ1A; MED27; SREBF1; TAF11; WIZ; NFE2L2; ZNF146; ARID1A; RNF10; RUVBL2; HOXB6; ZNF668; TGFB1I1; EDF1; LITAF; USP16; HOXD1; CREG1; ZNF576; ZNF83; COPS2; ABL1; ZNF263; PPRC1; RFC1; ABT1; PRPF6; ZBED1; ZNF768; SUZ12; AIP; CNOT3; TEAD3; CDC5L; CCNC; WWC1; PREB; MTA1; ENY2; PHF2; TAF6; C1D; ZNF787; PMS1; CARM1; NFYA; CEBPG; MED24; FOXF2; ZNF16; SRF; RCOR1; NFE2L1; PSMC3; TFAP2A; ZBTB48; SCMH1; TCEA1; TRIM29; RFXAP; CHD8; SP3; TRIP4; ILF2; SAFB2; NRIP1; ZNF444; LDB1; PAXBP1; CIZ1; MITF; TOB1; TULP3; E2F2; ZFX; HOXB3; SUPT6H; CITED2; RRN3; APEX1; SREBF2; SUB1; HMGB1; ZNF580; RNF6; VGLL4; PCGF2; RNF2; SP100; PSPC1; SMARCB1; JUND; KAT2A; HSF4; CREB3; DEK; TRIM27; PITX1; CTCF; TADA3; TAF1D; BIRC2; ZSCAN5A; SIRT7; GMEB1; ZNF467; SMARCA4; MED15; SIN3B; CTBP1; RHOA; MXD4; TRIB3; ZMYM2; ZNF232; NSD1; PEX14; CHD1; GTF2F1; TTF1; TRIM16; PA2G4; TRIP6; DEAF1; SLC2A4RG; MED6; GLI3; EWSR1; RBFOX2; SMAD4; ZZZ3; ZNF512B; HIRA; NEDD8; PTRF; OSR2; MLX; NFKB1; GCFC2; RXRA; MYNN; ZNF133; TFAP2C; ZNF217; CTBP2; TAF9; SNW1; CREB1; CNOT6; MED1; KAT5; PTTG1; HMGXB3; RXRB; HSBP1; PLAGL1; BRCA1; HDAC3; ZBTB7A; MED23; UBE3A; SAP18; ZNF354A; TFAM; NR2F1; PSIP1; HIVEP1; TRIM28; DAXX; RAD21; GTF2IRD1; ZFHX3; C1QBP; TFEC; SUPT4H1; PBRM1; KDM5C; SPI1; PIAS4; BAZ1B; ZNF410; ZNF24; SMAD1; TRIM32; TBP; GMEB2; UIMC1; FOXP3; ZNF337; HES1; CENPF; SOX11; ATF6B; POLR3C; SOX4; ZNF205; ZNF468; NR1H2; ARRB1; HOXA11; CNOT1; MED21; VEZF1; ZNF639; NCOA4; NR2F2; TBL1X; POLR3F; TSC22D1; AES; CBFB; ISL1; ZNF250; ZNF174; JUNB; MXD3; ZMYND11; RCOR3; HOXA10; MYF5; BRD3; MEIS2; SIX6; MMS19; GTF3A; ITGB3BP; ZNF131; SIX2; SPEN; ERBB2; ZNF143; FOS; MED20; TFAP4; ZMYND8; SETD2; BMI1; CIR1; REPIN1; HOXB7; SOX9; ZNF74; BAZ2A; HOXD11; BRIP1; TCF12; SHOX2; MXI1; FOXM1; ERF; AR; ZNF551; E2F6; ZNF3; ZNF646; CBX8; ZEB1; HSF2; HR; TCEB2; HOXD10; RAN; HMG20B; TFCP2; REST; PIAS1; SMARCE1; HDAC2; ELF1; SOX12; NR0B2; PBX3; NFIC; BATF3; USP21; THAP1; RNF14; MYCBP; TOX; RBBP8; TRRAP; BACH1; EN1; ZNF629; HIPK1; MZF1; CERS4; PSMC3IP; FOXF1; TDP2; WHSC1; BCL6; SPDEF; TCF21; BRD4; E4F1; BAZ2B; TLE4; ACTL6A; IKZF5; NPM1; BNC2; MYT1; BTAF1; IRF7; ELF2; NFYC; HOXD9; GLI2; PATZ1; ZNF32; ZNF44; TRAK1; FOXL2; TOPORS; HOXB13; AATF; BRD8; ZNF688; HDAC4; HIPK3; HNRNPD; HMGA1; PCGF3; ZNF394; PHIP; SIX1; TDRD3; MEIS1; KAT2B; ZNF516; MAFB; UBE2I; TAF10; CUX1; STAT6; CRY1; ORC2; NFATC4; DLX2; TERF1; ZNF652; BASP1; GTF2I; MSX1; HEY1; PAX6; CEBPA; ST18; EHF; CARHSP1; VPS72; ZKSCAN1; HHEX; ATF3; PPARD