Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75163	Azd-7762	GSE92742	MCF10A	Human	6h	2uM	EID0433

Response Information :

Types	Number	Response transcription factors
Up-regulation	97	RELB; ZMIZ1; FOXJ3; NFATC4; ZNF148; HOXB5; LEF1; RERE; PLAGL1; SIAH2; CBX5; ZNF587; NANOG; FOXO1; IRF4; CALCOCO1; NCOR1; E2F5; ATN1; POU4F1; AGO2; YAP1; IRF2; AR; ZNF266; TBL1XR1; PBX1; EP300; HMGB1; BCL3; PNRC1; ZHX2; CITED1; ZSCAN18; SMARCA1; KAT7; RBBP7; HMGB3; NFIC; PLAG1; PRKDC; TCEA1; NFX1; BACH2; RAD21; HOXB13; HOXB6; PBXIP1; TFCP2L1; TGFB1I1; MEIS1; TBL1X; ARNTL; ZNF117; CHD9; GTF2IRD1; TGIF1; CREB3L2; TCF7; THAP10; HIPK2; CREBL2; SREBF1; NR4A1; PBX3; CREM; RCOR3; HOXB2; TEAD4; ZNF160; ZNF721; BRD8; SPIB; HMGB2; INSR; DDX17; PEG3; ARID1A; ZBED2; REL; ZNF331; CREB3L1; WT1; IRF6; ZBTB16; ZBTB38; ZBTB18; TBX3; HOXB7; TRPS1; TLE4; ZNF44; RBPMS; FOXN3; RORA; NR4A2; HMG20B
Down-regulation	110	CDK9; HCFC2; ZNF124; KLF4; CCNE1; UBE2L3; MDFI; ZNF668; ELF1; BRIP1; TSC22D2; ZNF263; MNX1; HIC2; THRAP3; SAP30; RLF; MAFB; ANKRD1; XRCC6; MED6; BAZ1A; PRDM4; PTRF; SAFB; ZNF350; ZEB1; CENPB; DDX54; THAP1; TEAD1; MECOM; TOX; ZNF14; KDM5B; ZBED4; ATF1; SRF; SND1; ZFP36L2; RUNX1; CBX6; SMARCA4; TFAM; MED15; PML; MED17; ARL2BP; ST18; KLF2; CARM1; TDRD3; PBX2; IRF8; HOXD1; GATAD2A; OSR2; IFI16; MED1; HIPK1; EGR3; FLNA; ZNF423; ZBTB7A; MITF; ZNF711; KDM5D; SHOX2; SERTAD2; AATF; MTA1; SMAD3; HIRA; NAB1; BTAF1; MYRF; TOB1; HEY1; HMGA1; MNDA; TAF10; NR2F1; E2F8; SP3; MSX1; HDAC9; COPS2; RUNX3; JUP; SOX9; STAT6; CRY1; EMX2; SOX17; C1QBP; NCOR2; CRK; VPS72; NFIB; ZNF394; NFE2; SFPQ; JUN; SUB1; CARHSP1; ZNF91; ZFPM2; ZKSCAN1; CEBPA; PPARD