Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75162	Azd-7762	GSE92742	MCF10A	Human	6h	10uM	EID0433

Response Information :

Types	Number	Response transcription factors
Up-regulation	163	FOXO3; GATA3; TP53; ZNF14; ZNF287; ZNF329; MECOM; FOXA1; ZBTB6; ZNF274; TFEC; NFKB2; ZSCAN9; KDM5B; TAF7; ZSCAN31; ZNF304; ZNF492; ECD; ZFY; HOXC6; MDM2; ZFHX3; NR1H4; TAF12; ZNF180; TOPORS; SNIP1; ZNF571; PBX2; RBBP5; RXRG; HOXD11; NR5A1; ZNF214; ZNF263; NR3C2; TAF1A; ZKSCAN3; ZNF75D; TXNIP; TAF9B; ENY2; CCNT1; MED23; ZNF12; HMGB2; ADNP2; PRDM5; L3MBTL1; ZNF682; ZNF33B; ITGB3BP; ZNF536; ZNF165; SOX11; HOXB13; BHLHE41; ZBTB43; ZNF184; ZSCAN16; WWP1; DAXX; RERE; KDM5D; ZNF529; ZNF10; MDM4; SCAI; REPIN1; TSC22D3; HEY2; ZNF124; BBX; HOXC11; EDF1; TGS1; SCMH1; MED7; MXD1; UBE2B; BCLAF1; CITED2; POU4F1; ZNF226; ZNF606; SMARCA1; BLZF1; ZNF134; LIMD1; TCF21; FOXF2; TERF1; MBD2; CREM; ZNF551; BRD2; ING2; ZNF227; TCEB2; ZNF268; NFE2L2; AR; NR4A2; CBX7; SUPT4H1; RSF1; ISL1; KAT7; THAP10; TBL1X; POU2AF1; TFCP2L1; ZNF112; EYA1; MEOX2; NFAT5; ZNF107; HOXC10; YBX1; NONO; NFE2L3; NR2F2; CREBL2; ZHX2; DACH1; ZNF835; SHOX2; ASCL1; ZBED2; RNF14; ZNF248; PHIP; ZBTB20; HMGB3; BNC2; FOXE1; REL; HMGN3; PURA; ZNF189; PEG3; CAMTA1; ZNF611; JUN; TBX3; FOXF1; SUB1; PITX1; ZBTB16; NKX2-1; RBPMS; ZNF721; ZNF44; ZNF331; ZNF160; MYBL1; TOB1; WT1; SMAD2; ESR1; ZBTB38; HMG20B
Down-regulation	183	PUF60; ADRB2; TLE1; TRIB3; YAP1; ATF5; BAZ1A; VDR; CCNE1; DR1; HDGF; TFCP2; MKL1; FOSL1; KAT2A; CEBPG; FOXN2; MED27; SSRP1; MED16; TTF2; SF1; RXRA; KAT8; IRF3; TBP; RUNX1; TGFB1; ZNF410; ESRRA; VGLL4; ATN1; MLXIPL; TERF2; HLX; HOXA4; DEAF1; RFXANK; UBE2L3; CAMTA2; BATF3; PSPC1; RYBP; BRD4; ZMIZ1; CHD7; NUP62; PREB; ZSCAN5A; NAB1; EED; SMAD1; RELA; ELF1; SNAI2; LMCD1; TCF12; TAF4; GTF3A; YAF2; NFIB; KMT2B; ALX1; MTA1; ZNF22; TRIM28; RUVBL2; ID3; ARNTL2; NCOR2; NFRKB; ZNF143; NFYC; SMARCB1; MED6; HIPK3; IRF8; PMS1; MSX1; TRIP6; ATF1; NRBF2; FLNA; MNT; RBM14; CNOT3; XRCC6; AIP; ATF2; PLAGL1; DPF2; BIRC2; SMARCA4; PATZ1; SOX4; TRIM29; JUNB; SUV39H1; BRCA1; ARID5A; PPRC1; BATF; MLX; HDAC9; STAT3; ZMYM2; APEX1; SFMBT1; KLF11; ZBED1; CBFB; CREB1; SERTAD2; MED21; ZNF282; TEAD1; TAF10; TRAK1; ZFP36L2; ETS1; IRF7; PROX1; TCF3; ZNF146; NCOA6; NKX3-1; KDM2A; ZEB1; MED15; SETD2; HIVEP2; EGR1; TFE3; ETS2; MEIS1; KLF4; HTATIP2; MED24; ELF4; HEY1; TLE4; C1QBP; RNF111; PPP1R13L; NFIC; TFEB; HMGA1; CARM1; BASP1; NFE2; FHL2; MYRF; BTAF1; SPEN; CAPN15; TSC22D4; ST18; FOXA2; PDLIM1; TULP3; BMI1; PAX6; RNF141; PAX5; ERBB2; BAZ2B; CRY1; NR2F1; MYB; SMAD7; KLF5; RORA; SOX17; SATB2; ATF3; SMARCA2; TWIST1; EMX2; CEBPA; FOXN3; SOX9; VPS72; PPARD