Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75155	Saracatinib	GSE92742	MCF10A	Human	6h	2uM	EID0433

Response Information :

Types	Number	Response transcription factors
Up-regulation	95	TBP; SATB1; TP53; NFKB2; ZNF33B; MYCN; LEF1; TBX2; HOXC10; RBPJ; RXRB; ZZZ3; BCL11A; RFX5; PRMT2; TAF11; SIAH2; ZNF468; ZHX2; PAX8; IRX5; MED23; DAXX; ZKSCAN4; HOXC6; TCF25; EYA1; HMGN3; NFYC; FOXF2; SSBP3; CNOT6; MDM2; TRIM29; CBX5; HOXB13; PHF1; ZNF467; BRCA1; BCL6; CREBL2; CREM; RBBP8; BANP; FOXF1; DDIT3; TBL1X; ZNF239; HOXB2; SIX2; SIX1; NR2F1; MEIS2; SALL1; TULP4; ZNF148; CITED1; MXI1; CIZ1; PEG3; NPM1; HMGA1; BHLHE41; POLR2A; ELF3; ZEB1; STAT4; BNC2; PHIP; ZNF248; SUPT3H; IRF1; THAP10; TSC22D1; CBX6; MGA; MYCL; SP3; ZNF184; SOX10; KMT2A; TBX3; CAMTA1; AHR; ZIC1; HLF; NR4A2; SHOX2; EZH2; MYBL1; ESR1; HOXA5; WT1; ATF3; HMG20B
Down-regulation	67	FOXO1; PMF1; LMCD1; FOSL1; PRKDC; SCAND1; HIF1A; FLNA; NFKBIA; XRCC6; ADRB2; ID3; GATA6; GABPB1; TAF1D; FLI1; TAF4; NR1I2; MSX1; RBBP7; LOXL2; RAN; NCOA6; ATF4; RHOA; TSC22D2; TGFB1; ZMYND8; NCOR2; MAF; CREB1; PTRF; AEBP1; ZNF532; SREBF1; CNBP; SMAD7; TOB1; ZNF217; ZMYM2; HIC2; ZBED2; BASP1; ZBTB16; NR1H2; VEZF1; BMI1; SPEN; MED1; HDAC9; PDLIM1; KLF11; ZFP36L2; ELF4; PBXIP1; ZBTB18; INSM1; JARID2; HEY1; ST18; ERBB2; FOSB; MAFB; VPS72; FOXG1; NKX2-1; ZNF91