Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75148	Tivozanib	GSE92742	MCF10A	Human	6h	10uM	EID0433

Response Information :

Types	Number	Response transcription factors
Up-regulation	414	IKZF1; MEF2C; EGR2; NR3C2; MNAT1; PPARG; CHD7; ZNF586; SSBP2; ZEB2; ZNF253; TULP4; SATB1; ZNF93; HNF1B; MXD1; ZNF701; IRF4; ZSCAN18; NR1I2; ZIM2; NANOG; IRX5; EP400; URI1; KDM5D; ZNF671; ZBTB39; HEY2; SMARCA5; CDX1; TSG101; E2F5; ELF3; ZBTB18; PLAGL2; HLX; TXNIP; WHSC1L1; PRMT2; BCOR; ZNF443; ZNF329; NCOA1; BHLHE41; NFIX; NEUROD1; EYA3; ZNF117; ZFY; TMF1; SHOX; NFAT5; ZNF132; PEX2; BRWD1; POU6F1; SKI; MSC; ASH2L; SMAD5; PLAG1; IL16; IFNB1; RSF1; HCFC1; SALL2; ZBTB43; KLF4; TBX2; SNIP1; ZKSCAN7; HCFC2; ZNF415; ZNF506; NRBF2; MED31; TWIST1; MED7; ZBTB14; BRD7; GBX1; IRF2; ID2; ZNF573; ZNF654; TFE3; ZNF136; ZNF135; NEUROD2; SMARCD3; LZTS1; ZBTB7B; ZSCAN9; CDX2; NLK; ZBTB44; KLF15; CARF; NR6A1; RELB; PRDM5; SMAD7; KDM2A; NCOR1; OVOL1; DMTF1; ZNF273; SOX10; HMG20A; RUNX1; TRIM22; PRKDC; SATB2; ZNF350; NFRKB; PURA; ARID3B; ZNF75D; NCOA2; TGS1; TEAD1; ZNF835; SAP30; KDM4A; RARG; ARNT; BCL10; PHOX2A; MECP2; TFAM; ZNF236; ZNF667; RFX2; STAT2; PRDM14; MAX; HOXA1; GFI1; ZNF606; RBPMS; DNMT3B; SOX5; NR0B1; BARX2; CCNE1; ID4; ZNF195; ZNF510; MKL1; ZNF43; KLF13; CHD2; SOX21; SSX1; ZNF536; TRAF6; YBX2; ATOH1; ZNF440; ZNF587; HOXC8; XBP1; PIAS2; POU5F1B; NR1D2; TSC22D2; KDM5B; NFYB; STAT5A; PPARGC1A; TERF1; EED; L3MBTL1; HOXC5; ING2; RBBP5; EPAS1; KMT2D; TFDP2; CBX2; ZNF528; RB1; KLF12; SMARCD2; SSBP3; EP300; PRDM8; TFCP2L1; MLXIP; ZNF248; PAX7; CTR9; CREB3L1; LHX3; SMARCA2; IKZF3; ZNF552; ZNF665; TCF20; ZNF202; PROP1; PSMD9; ZNF223; NPAT; HDAC11; ZNF492; KMT2A; PRRX1; POU2F2; NFYC; ARID4A; NR3C1; ZBTB25; EVX1; ZNF141; CBX5; ZNF287; SNAI1; ZNF35; PRDM10; ZNF507; ZFHX4; TRRAP; MEOX2; CTNNB1; TP53; HMGB3; ZMIZ2; KDM5A; EGR4; FLI1; HOXD3; ZNF282; HOXD1; ZNF222; SUPT7L; RERE; ADNP; BATF; NFIC; ZHX3; TAF1; ZSCAN32; NEUROG1; MYB; AEBP1; HDAC6; ZNF778; PFDN5; SAP130; ZNF107; KLF9; ZNF816; TAF12; BACH2; ZNF493; PAX1; ING3; RARA; ZKSCAN4; ZNF175; DDX17; SMAD4; PGR; KAT5; WT1; OLIG2; ZNF419; MLLT10; CCNT1; TLE4; ZNF764; IRF5; KLF6; CDIP1; BBX; SAFB; ZNF134; ZNF529; LIN28A; CEBPG; ZNF286A; STAT4; ETS2; FOSL1; RFX7; REST; SMARCE1; EBF2; NR2E1; CIR1; MTF1; TAF5; NR1H4; PIAS3; BNC2; GLI2; ZNF571; EHMT1; ZIC3; FOXE1; TRIP11; CREB5; LPIN2; MYT1L; HIPK2; POU3F1; INSR; BRCA1; EYA1; E2F3; TAF7; NUP62; TCFL5; NPAS2; RNF111; SOX4; SMAD6; SUV39H1; NFKBIB; CREBL2; RBL2; ZNF302; MYCN; MED20; ELK1; BHLHE40; ELF1; TRIM24; HTATIP2; LIMD1; PLAGL1; FOXG1; OVOL2; NR2C2; CXXC1; SMARCA1; DDIT3; PBX2; MAF; TDRD3; EGR3; HEY1; ZNF85; AFF1; BLZF1; PROX1; ZNF430; EGR1; MEN1; FOXN3; BRD4; SOHLH2; TRIM25; PBX3; KLF2; HOXB2; PHF8; ZNF177; PKNOX2; EZH1; SOX11; ZNF264; SMAD2; SMARCA4; FOSB; GATAD2A; ANKRD1; GLI3; KMT2B; STAT3; DACH1; ELF2; ETS1; BLM; BCL11B; CREM; ZNF217; ZNF266; ZBTB38; MKL2; ASCL1; EYA2; TCF4; ZIC1; TCF12; MAFG; PAX6; CBX7; MBD4; ZNF331; BTG1; CHD3; PAX8; CBFA2T3; YWHAB; MGA; PRDM2; HMGA2; GTF2I; NFATC1; PBXIP1; NFIL3; ZNF224; POU2AF1; EZH2; KLF5; MYCL; SOX17; VPS72; PPARD; ZNF91; CRK
Down-regulation	387	DRAP1; CEBPB; ATF5; PCGF1; MYC; IKBKAP; IRF3; ARID4B; PMF1; DNMT1; RFXANK; RUVBL1; ZNF576; ZNF593; TCF25; CEBPZ; ZBTB17; RNF4; DR1; THAP7; TFAP2A; SCAND1; MDFI; WWTR1; MXD4; ARNTL2; CBFB; HDGF; JUP; ERF; CBX4; SP140L; RUVBL2; ZFX; TLE1; SRCAP; ZMIZ1; ZNF580; MED16; ZNF263; APEX1; HDAC1; RBBP7; BCLAF1; SP110; THAP4; ETV4; CREG1; ZNF335; XRCC6; ZFP36L1; CSDE1; UBE2L3; MED27; CNOT1; ZNF668; HSF1; FUBP1; RFC1; TAF5L; ZNF16; ZBTB11; ACTL6A; TEAD4; HDAC3; GMEB2; ERCC3; NOC2L; MYF6; IRX4; STAT6; RFX5; RNF138; MTF2; YAP1; MECOM; PMS1; MAZ; TAF6; PRPF6; EDF1; SAFB2; SUB1; PHF1; PHF2; MTDH; LITAF; ABL1; C1D; KAT2A; CREB3; CNBP; TEAD3; NEDD8; ENO1; AES; IRF8; MTA1; FLNA; CENPF; ZNF32; TAF1D; VSX1; DEK; NELFB; RNF2; HMGXB3; SIRT2; MED15; CERS4; PSPC1; USP21; FOXJ3; CEBPD; BRD2; LDB1; ATF2; DLX2; ZNF557; CENPB; SIRT7; ZSCAN5A; VGLL4; EWSR1; NKRF; KLF1; ARHGAP35; RYBP; RXRB; ARID1A; YBX3; RCOR1; ZNF74; NR0B2; NRIP1; CRY1; HIRA; HSF4; PA2G4; WDR77; REXO4; PIAS4; ZBTB7A; DAXX; ZNF12; TRIM16; SLC2A4RG; JUND; ATF4; MYNN; ZBTB48; COPS2; AIP; FOXK2; VAX2; RING1; MAFB; RHOA; CBX8; ZNF7; PREB; ELK4; CEBPE; NFYA; ZNF574; SRF; MZF1; HMGXB4; LBX1; KAT8; ZNF384; MYF5; ZHX2; ZZZ3; CDC5L; CCNC; PTRF; GCFC2; PSIP1; PIAS1; BCL3; WWC1; ELK3; ZNF512B; PAXBP1; ZNF672; HES1; ERCC2; RFXAP; TAF11; ZBTB32; SPEN; CDK9; GTF3A; TRIP4; RBFOX2; TCEB2; REPIN1; DNAJC2; CCDC59; STAT1; RNF6; NAB2; ZNF551; SIX6; GATA6; UBE3A; ZBED4; RXRA; ZSCAN31; BRCA2; ZNF473; SIN3B; TULP3; SUPT3H; HOXA7; ARL2BP; RAD21; OSR2; ZNF45; TRIM27; NR1H2; MED17; ARID5B; SMARCB1; TTF1; RAN; CDYL; DNAJC1; HOXB3; MED6; ENY2; HMGN3; SHOX2; SUPT6H; FOXF2; ZNF34; MEIS2; CREB1; ZNF787; HDAC4; CREB3L2; ZSCAN12; ZNF131; HMG20B; CTBP1; HIF3A; ZNF467; PEX14; RNF10; CARM1; NR2F2; PIR; ISL1; MED21; TCF3; ZBED1; BIRC2; EN1; CNOT3; ZNF646; ZEB1; ZNF232; BRIP1; ZNF589; SMAD3; CHD9; BRD8; USP16; MSX1; ZNF629; ZNF133; TAL1; PITX1; HOXA10; LOXL2; SREBF1; TTF2; ZNF410; KLF11; TERF2; ZMYND8; TGFB1; TOB1; GTF2F1; KAT2B; SIAH2; BARX1; MYRF; SPI1; CASZ1; CALR; ZNF3; ERBB2; PQBP1; ZBTB20; RRN3; ZNF143; CAMTA1; MYT1; FOXL2; TLE2; NR2F1; BMI1; HOXA5; ITGB3BP; MXI1; RXRG; TAF1C; PAX5; NFE2L1; TCF7L2; PTTG1; PBX1; EMX2; ZNF83; SMAD1; ZBED2; ESRRG; ZMYM2; ZNF532; FOXM1; SFMBT1; ILF2; IKZF5; ZBTB1; RCOR3; ESR1; LHX1; RBBP8; HOXD10; CBX6; ETV5; ZKSCAN5; PNRC1; NPM1; NCOR2; ZNF394; CARHSP1; HDAC9; MNT; TCF21; BAZ1A; SOX9; HDAC2; BANP; ZNF112; RREB1; ELF5; SOX13; WNT4; HOXB7; CUX1; KLF10; BTAF1; ID3; TAF10; NR4A1; ZNF239; INSM1; HMGB2; TOX3; TRIM28; E2F8; NFIB; IRF6; THAP10; NFE2; HMGA1; ERG; HSBP1; ZNF652; TRIM29; TBL1X; JARID2; TFAP2C; IFI16; C1QBP; TCF7; FOXF1; ZNF189; EHF; MEIS1; MED1; SPDEF; CEBPA; HHEX