Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75136	Motesanib	GSE92742	MCF10A	Human	6h	10uM	EID0433

Response Information :

Types	Number	Response transcription factors
Up-regulation	129	NFKBIB; NFKB2; SMARCA1; IRX5; NFATC4; DMTF1; ID2; HOXC10; EYA1; ID4; SALL1; URI1; CBX4; DR1; TCF7L2; DAXX; ETV5; RBBP8; TGIF1; ELF3; ESR1; PAX8; PIAS3; IRF5; ZNF329; CHD9; PSPC1; NCOA1; MYB; ZNF148; RERE; TAF12; HLTF; ZNF571; ABL1; ZNF443; DBP; TCF12; PHIP; SERTAD2; WWTR1; ERF; ITGB3BP; PLAG1; ZFHX3; NFE2L2; CREM; DACH1; CIZ1; HOXB2; GRHL2; SP3; JUN; ZZZ3; FOXA2; ZFP36L1; ZNF467; BCL11A; CREB3L2; CBX5; ZSCAN18; TXNIP; TRIM32; HMGA2; NFKB1; PMS1; BCL6; SUPT3H; PHF1; E2F5; SIAH2; HMGN3; EYA2; MBD2; REL; PRRX2; ZNF184; ZBTB20; BHLHE41; MNDA; HHEX; DLX5; POU4F1; NR1D2; HNRNPD; WNT4; ZNF117; NELFB; AR; SIX1; TRPS1; HMGB2; OSR2; NFE2L3; GTF3A; PLAGL1; BAZ2B; PURA; ING2; NAB1; TOX3; TLE2; PTTG1; AES; TCF4; KAT6B; PCGF2; RARA; BMI1; HOXA11; TRIM28; TBL1X; YEATS2; OVOL2; HSBP1; SIX2; HOXA10; MXI1; POU2AF1; ZBTB38; CTBP2; NKX2-1; KLF11; HOXB7; NR4A2; TFAP2C; NR2F2; CEBPA; MEIS2
Down-regulation	85	PRKDC; ZNF557; TTF2; NKX3-1; MDFI; PSIP1; SOX15; TMF1; MLXIP; RYBP; EGR2; FOXO1; JUND; FOSL1; NCOR2; HOXA7; ETV1; ID3; KLF7; RAN; ZNF500; NCOA3; NR2E1; LITAF; NANOG; ARNTL2; HOXD1; ZNF195; MTA1; LZTS1; FOXM1; CNOT2; TOX; BLM; NR4A1; ID1; MECOM; FLNA; TFCP2L1; BRD4; ZNF302; EGR4; EGR3; KLF13; GATAD2A; TEAD4; MAFB; TAF10; MED21; NFIB; ATF1; MED1; NKX2-2; NFATC3; STAT6; ZBTB16; SNAI2; KLF5; TRIM29; CUX1; SMAD1; TP63; TULP3; CAPN15; TRIM22; HEY1; TWIST1; ZNF224; STAT1; SPEN; ZNF721; ZNF91; CRY1; ELF4; FOXG1; AEBP1; TCF7; YBX3; TSC22D1; ZFP36L2; BCL11B; VPS72; TLE4; SMARCA2; SPIB