Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75119	Alvocidib	GSE92742	MCF10A	Human	24h	0.4uM	EID0432

Response Information :

Types	Number	Response transcription factors
Up-regulation	128	TSC22D3; CDIP1; ZMIZ1; PEX14; TFAP2A; ETS1; VGLL4; KDM5A; NFATC4; MNT; CDX1; ZNF423; CUX2; TDP2; FOXO3; BANP; DACH1; GON4L; ZNF79; BIRC2; SOX3; ZNF24; NFATC3; HOXD1; SUPT5H; ZKSCAN4; PIAS4; ZNF23; ING4; ZNF232; ZNF200; SERTAD2; ZFP36L2; PPARD; TOB1; SP2; BRD4; DDIT3; NEUROD1; MDM2; ZNF91; MXI1; ELF4; CRK; E2F3; ZBTB7A; INSM1; CIR1; KLF10; ARNT2; KLF3; ZNF117; HBP1; VPS72; KLF11; CBFA2T2; INSR; ZNF43; CREBL2; ZNF552; ZNF165; PAX6; RARG; PHF20; TCF7L1; BHLHE41; NFATC1; NUP62; GATA6; NFE2L1; DAXX; JUP; TWIST1; TOX; ID3; FOXJ3; MAFG; TERF2; CEBPG; FOXO1; JUND; MAFB; HIRA; BACH2; WT1; ZFPM2; ZNF426; IRF6; TULP3; TXNIP; TGIF1; CHD4; SUPT6H; KLF5; ZNF711; NCOA2; TRPS1; DBP; KLF7; ST18; KLF13; ID4; NR3C2; ATF3; MECOM; RXRA; IRF9; CDYL; TLE1; HLX; POU2AF1; PNRC1; IRF7; ZNF589; SOX13; FOXF1; SMAD3; MAF; TCF21; ERBB4; SMAD1; OSR2; CTBP2; BTG1; SOX9; KLF9; ZBTB16; PDLIM1
Down-regulation	143	CCNA2; EZH2; HMGA2; IKBKAP; SMARCC1; ATF1; NPM1; CENPF; HOXC6; GTF2A2; ETV4; GABPB1; UIMC1; ETV1; PTTG1; PCBD1; TCERG1; ARNTL2; BCLAF1; ZNF32; BAZ1A; AES; PPARG; ORC2; RBM14; ETV5; TADA3; HDAC2; NEDD8; USP16; BMI1; PMF1; PBRM1; APEX1; SLC2A4RG; TCFL5; EGR1; MEF2D; SSRP1; PHF2; WDHD1; CARHSP1; PAX8; PITX1; NFX1; ECD; NR2F2; SUB1; ITGB3BP; FOSL1; HDAC7; HES1; RUVBL2; CBFB; SMARCA2; FHL2; RBPMS; STAT5B; SOX4; ZNF532; DDX54; SP3; GCFC2; BRCA1; RBBP7; TAF1D; C1QBP; CALR; CIC; TRIM32; JARID2; ZMYND11; SFMBT1; HMGB1; MAGED1; DNMT3B; ZNF551; PURA; SMARCD2; EED; POLR2A; CHD3; TRIM28; STAT6; TRIP6; PMS1; CHD9; YWHAB; ZBTB11; NR4A1; ZNF124; ELK3; TAF10; BLM; IFI16; TFCP2; BRD3; TBL1XR1; MAFF; PSIP1; KLF2; BATF3; MAML1; NLK; HOXA10; SIM1; RBBP4; CENPB; TFAP2C; E2F8; RFX5; UBP1; STAT1; SMARCA4; SIX2; NFKB1; ING3; JUNB; PLAGL1; TRRAP; LOXL2; HLTF; HOXC10; IRF4; PCGF2; TLE4; HMGA1; AFF1; MTA1; RERE; ZNF226; ZBED2; ETS2; SMARCA1; NAB1; MEIS1; SOX11; WWTR1; TOX3; EGR3; CITED2; NFKB2; SUV39H1