Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75118	Alvocidib	GSE92742	MCF10A	Human	24h	2uM	EID0432

Response Information :

Types	Number	Response transcription factors
Up-regulation	210	EGR1; NR5A2; GLI2; NFATC4; ATF3; ZIC3; CDIP1; PPARD; ZNF423; INSM1; ZNF75D; ETS1; TTF2; TFAP2A; SOX17; SOX2; ZNF117; ZNF816; CUX2; ERBB4; NR4A1; FEZF2; TWIST1; BHLHE40; HOXB1; THRB; RB1; IRF1; BARX1; NHLH1; SHOX2; LIN28A; HBP1; NHLH2; CEBPE; ARL2BP; NEUROG1; RING1; ZMIZ1; ZNF711; TRPS1; E2F2; ZFPM2; HOXA3; TSHZ2; THRA; MECOM; SND1; TBX21; SOX3; PRDM1; TERF1; RSF1; DLX5; HOXD1; ZNF141; ZBED2; PRDM12; SPI1; PRDM14; FOS; ZNF701; HAND2; WT1; LHX3; ZNF562; HOXD3; LZTR1; MEIS2; NR5A1; KLF7; CALCOCO1; CREBL2; MED12; NFATC3; IRF6; ZNF345; MYCN; MXI1; TCF7L1; EHMT2; ST18; BACH2; GBX1; ID3; ZNF682; ESR1; NR0B2; HEY1; SPDEF; HDAC9; HIC2; GATA6; VPS72; ZNF654; TCEA2; TGFB1; FOXO4; KAT2B; EP300; HMGN3; L3MBTL1; GLI3; SOX18; ZNF665; ARNT2; ZNF264; HOXA4; AEBP1; IRF9; ZNF667; ING4; PBXIP1; DACH1; ID4; SSBP2; ZNF586; ZNF532; ZNF611; PHF1; ZNF467; BIRC2; HLX; HOXB5; ZNF358; EGR2; CAMTA2; HIPK2; MED14; KDM5C; ARID3B; STAT2; ZSCAN18; EMX2; ZNF536; MYBL1; NCOA2; CDX1; RARG; MYRF; TCF21; SALL2; CREG1; JUP; CREB3L2; SUPT3H; NR2F1; TCEA1; SMARCA1; HEY2; LOXL2; ARID4B; ZNF415; DAXX; POU5F1B; ZNF426; FOXL2; LDB1; PBX1; PAX6; NR4A3; UBE2L3; TAL1; TFDP2; KLF13; PEX2; ATF2; PTRF; MAFF; BNC2; MAF; ZNF589; WNT4; TCF4; YEATS4; TCF7L2; SP140L; JUNB; DLX2; PBX3; FOXF1; FOXF2; AR; NFE2; STAT4; ZEB1; PLAGL1; PEG3; MEIS1; CALR; TOX; ID1; FOSB; IKZF1; ZIC1; CD3D; NR4A2; HOXB2; EGR3; PDLIM1; HOXB6; LEF1; ZNF331; TBX3; ZEB2; NR1H2; SATB1; NFE2L2; ARID5B; CITED2
Down-regulation	376	PUF60; MYC; CCNA2; USP22; FHL2; ZBTB24; CRK; HNRNPD; TBP; TCERG1; RBM14; ABL1; CDK7; ADNP; TRIM32; FOSL1; SNW1; GABPB1; ATF1; ADRB2; ZFP64; CENPF; CCDC59; NUP62; NFKBIB; XBP1; MLX; TAF4; MED6; NPM1; HSF2; PATZ1; SMARCD2; YAF2; ZNF16; SMARCC1; NELFB; TRIM28; BRPF1; EZH2; PTTG1; NKX3-1; ZNF473; SP3; DDX54; PMF1; ZNF384; MAGED1; VEZF1; HOXA10; TTF1; SFPQ; YWHAB; KAT5; VGLL4; ING2; RNF6; CTR9; HOXC6; ZBTB11; HOXA11; ERCC3; RBBP5; BRD8; FOXO3; ZNF443; ZMYM2; NFYA; CENPB; PHF8; IKBKAP; PLAGL2; ZNF212; SMARCD1; SNIP1; NFYC; TAF5; PURA; RBBP4; DPF2; DEAF1; CHAF1B; NRIP1; SIX1; DNAJC2; ZBTB1; REPIN1; TBL1XR1; ELK3; PSPC1; NCOA4; ZSCAN5A; SETD2; RUVBL2; SIRT7; TRIM16; RNF111; ELF2; ELF1; MEN1; CTCF; ZNF282; PHF20; PCGF2; LIMD1; ADNP2; ABT1; E2F6; PPRC1; CBX5; NPAT; ZBTB40; RAN; TRIM27; HMG20B; MED27; KAT8; RREB1; KDM5A; BCLAF1; ZNF408; KAT7; UBP1; UIMC1; KDM2A; ZNF672; SMARCA4; HCFC1; CDK8; ORC2; CEBPZ; ZNF227; MED1; MED17; UBE2I; AATF; ZNF7; KDM5D; BAZ1A; ZNF696; GTF3A; HCFC2; ATF7IP; ETV4; EED; AGO2; ERBB2; SIX2; TBL1X; NCOA6; TCF20; TCF12; NR2F2; PIAS2; DEK; ZNF263; COPS2; APEX1; FOXJ3; HDAC2; ERCC2; NFKBIA; RBPMS; ETV1; BLM; PHF2; CASZ1; BRCA1; PBRM1; POLR2A; ETV5; ZBED4; MED23; SCMH1; PCGF1; MED4; CEBPA; USF2; IRX4; BRD3; CHD8; SMARCE1; REXO4; HMGB2; TAF10; ZBTB7A; HMGXB4; CHD9; THAP1; TRIP6; NRF1; ZNF248; GTF2IRD1; ZNF146; MED24; SOX4; TMF1; NFX1; MNT; ASXL1; IKZF5; BAZ1B; ZNF14; IRX5; MEF2D; ZNF12; CITED1; ZNF23; FOXJ2; TSC22D1; TFAM; SAFB2; JARID2; TP53; ZZZ3; ZNF574; PRPF6; MAX; HMGB1; ZNF410; DNMT3B; MED16; YBX3; CRY1; NCOR2; MGA; POLR3F; HOXA5; SMARCA2; ZNF629; ITGB3BP; ZNF148; MYF6; ZNF143; BMI1; ELK1; AFF1; TRIP4; SAP30; ZNF337; ZNF266; HDGF; NCOR1; RBBP7; SSRP1; ZBTB25; RFX5; NSD1; SF1; REST; TSC22D2; CBFB; ZNF394; RNF138; NFKB1; ZBTB18; PPARG; TLE2; TEAD4; ZNF45; SMAD5; TFAP2C; SIAH2; HMG20A; ZNF202; TADA2A; CLOCK; HR; RNF4; CARHSP1; ZKSCAN5; SMAD4; PA2G4; SMARCA5; ECD; ANKRD1; SMARCD3; CNOT1; MTA2; ARNTL; CBX3; ZMIZ2; CRYM; SFMBT1; NFRKB; RFX7; MTDH; USP21; ZBTB16; SERTAD2; PIAS3; KLF2; HOXC10; ATF4; SMAD2; ZKSCAN1; TBPL1; CARM1; CEBPG; THAP11; PMS1; LPIN2; MTF2; MAML1; ID2; POU2AF1; ASH2L; SIM2; CREB3L1; SUB1; MEF2A; SREBF1; GATAD2A; HIVEP2; FOXM1; CREBZF; PIR; TFCP2; ZHX2; TERF2; TULP4; ZNF652; TLE4; MBD2; CHD3; RCOR1; DNAJC1; NFE2L1; ZNF430; IRF4; TOB1; PITX1; CHD7; POU2F1; CHD1; ZNF189; RELA; NLK; RORA; SCAND1; EN1; MKL2; TSC22D4; BANP; PHIP; ZNF512B; ING3; RRN3; BCL6; WWC1; TRRAP; SMAD1; KAT6A; CDYL; ZNF302; CTBP2; ELF3; KMT2A; RNF141; SMAD3; SOX11; KLF4; CBX6; SUV39H1; TP63; FOSL2; ZNF274; PAX5; RBPJ; SOX9; ERG; NFIB; MITF; TLE1; BASP1; HES1