Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75115	Cgp-60474	GSE92742	MCF10A	Human	24h	2uM	EID0432

Response Information :

Types	Number	Response transcription factors
Up-regulation	224	EGR1; ATF3; TRPS1; ZNF264; NR5A2; PRDM1; ZMIZ1; SOX2; GLI2; ZNF816; ZNF117; CEBPA; CDIP1; SHOX2; ID2; SOX17; BHLHE40; RING1; PRRX1; PROP1; INSM1; ZSCAN2; THRB; ZFPM2; NFATC4; TSHZ2; MED25; CEBPE; BNC2; CREBL2; TTF2; ZNF345; HIF3A; PRDM14; IRF6; ZNF423; LZTR1; THRA; IRF9; ZNF136; ETS1; ZNF586; SOX3; HAND1; TWIST1; CERS4; MXI1; ZNF562; HOXA3; ZNF141; TCEA2; TFAP2A; PRMT2; ZNF552; CUX2; NEUROG1; CREM; HOXB1; ZIC3; ESR1; PBX2; ARL2BP; LHX3; ING4; RB1; NHLH2; PTRF; MEIS2; CALCOCO1; ATOH1; FOS; TBX3; ZNF350; AEBP1; HBP1; ZNF444; ST18; KAT2B; BARX1; ZSCAN18; TERF1; SALL2; ZNF835; HOXD1; FOXN3; FOXF1; ZNF768; ZNF665; LOXL2; FOXF2; CBFA2T3; HDAC6; PBX3; SUPT3H; NR4A1; ZNF415; HOXD3; ZEB1; HDAC9; RARG; ATN1; GATA6; SSBP2; ZNF667; AR; NR2F1; ZNF205; TBX1; ZNF536; TBX21; PBXIP1; SPDEF; ZNF682; CDX1; MYT1; SPI1; ZNF43; EMX2; GLI3; RSF1; ZFX; EHMT2; INSR; TULP3; ERBB4; WWP1; PAX6; HOXB5; HOXB13; ZNF93; MYBL1; ZNF85; MSX1; ZNF331; HEY2; NEUROD1; NFIL3; ZNF224; KLF3; ZNF268; HEY1; ZNF467; WT1; SSX1; MAFF; NFIX; ZNF623; WNT4; DLX5; ZNF358; NR4A3; KDM5C; TGFB1I1; BHLHE41; ZNF611; ZSCAN9; ARNT2; TGFB1; OVOL2; JUNB; NFATC3; ZNF91; NFIC; HHEX; LIN28A; ZNF654; ARID5A; VPS72; MEIS1; ID3; YEATS4; ID4; MYCN; ZNF140; ZNF587; LEF1; PBX1; KLF7; SP140L; ZBED2; CNOT3; MYCL; PEG3; MAF; CBX4; CDK2; TXNIP; CREB5; PHF1; EHF; PSMC3; TCF7; EGR2; OSR2; TCF21; PLAGL1; SSBP3; CD3D; ZNF532; ZNF589; SMARCA1; CALR; NR0B1; ID1; ZIC1; CERS6; CREB3L2; DACH1; HOXB2; HLX; EYA2; ZNF83; TOX; NR4A2; HOXB6; TFDP2; MYRF; IRF7; IKZF1; JUN; NR1H2; DLX2; KAT6B; MEF2C
Down-regulation	376	MYC; CCNA2; USP22; PUF60; GABPB1; TBP; ZBTB24; RBM14; ADNP; NUP62; XBP1; YWHAB; CENPF; CRK; SIRT7; FHL2; TRIM32; TCERG1; SNW1; CDK7; ATF1; PLAGL2; FOSL1; NELFB; VEZF1; PPRC1; MED6; EZH2; BRPF1; SMARCC1; ING2; ZFP64; HNRNPD; CTR9; REXO4; YAF2; DR1; TBL1XR1; KAT5; ZNF672; PATZ1; HSF2; ABL1; CBX5; MLX; SP3; HOXC6; ZBTB11; KDM2A; HMGB2; CCDC59; HDAC2; PHF20; USP21; NR3C1; SMARCA5; RNF111; ZBTB7A; DDX54; TAF4; AATF; SNIP1; RNF6; NFKB1; SIX1; DPF2; BAZ1B; NCOA4; ERCC3; PHF8; TTF1; FOXO3; SIX2; BAZ1A; HMGXB4; ZBTB1; FOXJ3; ASXL1; SMARCE1; ADRB2; APEX1; NFYC; ZNF410; RNF138; HDGF; NFYA; PKNOX1; MED23; CEBPZ; UIMC1; SMARCD1; PMF1; ORC2; COPS2; ELF2; ZBTB18; ZNF473; SMARCA4; MEN1; HOXA10; CNOT1; RBBP4; SETD2; NPAT; CARM1; SOX4; UBP1; SFPQ; BRD8; WDHD1; ZNF7; ARID4A; GMEB2; MED17; BCLAF1; RAN; MED1; ATF7IP; NRIP1; MED24; AGO2; SAP130; KDM5A; NFKBIB; ERBB2; TSC22D2; DEAF1; IKBKAP; HMG20A; ZNF443; CBX3; ABT1; NKX3-1; CCNE1; MAGED1; TBL1X; ZBED4; KDM5D; ZNF212; TRIM28; ZNF16; TCFL5; ELF1; TBPL1; IRF2; BRD3; UBE2I; SMAD4; DNAJC2; CRYM; NCOA6; NFKBIA; KAT7; ZSCAN5A; JARID2; DNMT3B; CENPB; ZNF282; PPARG; SETDB1; POLR2A; RFC1; NRBF2; ZNF23; ZNF384; RARA; PSPC1; TRIM16; ZNF574; TCF20; GTF2IRD1; NR2F2; KDM5B; RREB1; ELK1; ZNF227; NR2F6; TAF5; SMARCD2; DEK; PIAS2; CHAF1B; RBBP5; C1D; TSC22D1; NFX1; RNF4; PURA; SAP30; ARNTL; BLM; CCNC; ZNF764; MED4; CASZ1; TFCP2; MBD2; EED; ZNF629; MTF1; RUVBL2; BRCA1; ADNP2; RBL1; ZNF146; THAP1; ATF6; HOXD10; TRIP6; MYT1L; TCF12; DDX5; SMARCD3; BASP1; RFX7; TEAD4; BAZ2B; TAF1A; NONO; CHD1; ZNF263; IKZF5; ILF2; ZMYND8; ZNF576; HCFC1; IRX4; TADA2A; TSG101; CTCF; SMAD3; E2F6; SCAND1; BIRC2; MED16; CRY1; NPM1; SFMBT1; NLK; RBBP7; CHD8; WWC1; MTDH; TRIM27; KAT8; TAF1D; BMI1; MAX; THAP4; TOB1; NFYB; UBE3A; SUZ12; HOXA11; ZZZ3; PCGF1; REPIN1; NFRKB; FOXA2; PHF2; GABPA; PMS1; FOXK2; HCFC2; HOXA7; PTTG1; MAFG; HOXB7; MKL2; ELK3; CREBZF; SMARCA2; MEF2A; REST; NPAS2; RFX5; ZNF248; PCGF2; ZNF202; ZBTB25; PIAS1; ZBTB14; ZNF3; XRCC6; CCNT1; MTF2; ANKRD1; BANP; PITX1; ZNF143; BATF; RUNX3; EYA1; CEBPD; SMAD2; SOX9; NFE2L1; TMF1; HOXC10; ZMIZ2; POU2F1; TFCP2L1; CDYL; AFF1; ZNF266; ZNF189; TFAM; ZNF337; MGA; HDAC4; ZNF593; YBX3; LPIN2; SERTAD2; TERF2; ECD; DDIT3; RBPMS; CXXC1; MSC; RBPJ; IRX5; BATF3; TRRAP; CHD7; ARID4B; NFATC1; HES1; MED13; TAF9; SIAH2; CTBP2; SREBF1; HIVEP2; TLE4; KLF2; PA2G4; TSC22D4; ZBED1; RCOR1; ETS2; DDX17; CEBPG; KLF6; TRAK1; KLF5; TULP4; ELF5; GATAD2A; KAT6A; TP53; HMGB3; HOXA5; VDR; SUV39H1; IRF4; PITX2; NAB1; KMT2A; CLOCK; FOSL2; HLTF; RERE; HIPK3; ING3; STAT6; BCL6; TLE1; FOXD1; RXRA; SMAD1; ERG; CITED2; SPEN; FOXG1; POU2AF1