Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75114	Cgp-60474	GSE92742	MCF10A	Human	24h	10uM	EID0432

Response Information :

Types	Number	Response transcription factors
Up-regulation	243	EGR1; GLI2; TRPS1; ATF3; CDIP1; ZNF816; CREBL2; NR5A2; ERBB4; HEY2; SOX2; SOX17; ZFPM2; ZIC3; MYCL; SSX1; ZEB1; NFATC4; CBFA2T3; THRA; PEX14; IRF9; CUX2; TCEA2; TSHZ2; MXI1; PBX3; ZNF835; SOX3; RING1; CERS4; ZNF264; CREM; PIAS4; ZNF671; NFATC3; ZNF177; MED25; ZNF75D; THRB; SP100; ZNF34; TCF7L1; ZNF117; SALL2; FOXF1; MEIS2; ZBED2; TFAP2A; ZNF682; TTF2; ING4; ZNF586; ZNF701; NAB2; HBP1; PEG3; DACH1; ETS1; BNC1; IRF6; SSBP2; CEBPE; BRWD1; TCF3; ZNF623; BNC2; PRDM2; WNT4; LHX3; SOX5; ZNF350; ZNF665; ZMIZ1; ID4; BARX1; KAT2B; ZNF232; NR0B2; PBX2; GATA6; ZSCAN9; ZNF467; ESR1; HDAC9; WWP1; ZBTB17; L3MBTL1; NR2F1; SHOX2; SMARCC2; CEBPA; ZSCAN18; EHMT2; SUPT3H; HIF3A; ZNF768; BAZ2A; FOXN3; BHLHE41; HDAC6; AR; TBX21; ZNF136; LZTR1; ZNF91; TBX1; ZNF141; ZNF345; AEBP1; AFF2; SMARCA1; ZNF273; HHEX; TULP3; ZNF43; ATN1; RSF1; ZNF423; RB1; ZFP69B; ZNF93; SIX6; SUMO1; ARID5A; CALCOCO1; NHLH2; PRDM1; MYB; WDR77; FOXE1; TERF1; HOXA4; STAT2; PBXIP1; PTRF; TGFB1; PRDM14; TCF21; TCF4; ZNF415; SPDEF; MED12; KLF3; VGLL1; ZNF175; YEATS4; FOS; NR4A1; HOXB5; FOXF2; PBX1; ZNF180; ZNF140; VPS72; MYBL1; EMX2; ZNF304; ZHX2; ZNF611; ZNF536; BACH2; ZNF85; SOHLH2; ZNF562; SP140L; HEY1; TBX3; INSM1; PRRX1; HAND1; MEIS1; TRIB3; CSDC2; ZIC1; REL; CAMTA2; KDM5C; ZNF195; TWIST1; PAX6; MYCN; SPI1; CDK2; MECOM; LEF1; TAF11; CNOT3; RARG; ZNF667; AES; CAMTA1; SALL1; IRF8; ZNF532; ARNT2; CREB1; RAD21; PKNOX2; ZNF331; ZFP36L1; HOXD1; PNRC1; TCF7L2; OLIG2; CALR; EGR2; ZNF107; TFDP2; BCL11A; PAWR; WT1; TLE2; NFE2L3; CREB5; HOXB2; NFE2; NCOA1; BHLHE40; INSR; DLX5; NR4A3; THAP10; MXD4; NR1H2; ZSCAN31; TOX; ST18; ZNF589; CREB3L2; PHF1; ASCL1; JUNB; TDP2; NR0B1; SOX11; OSR2; DLX2; CD3D; ZBTB38; IRF7; MYRF; MEF2C
Down-regulation	363	MYC; NFKBIA; CCNA2; PUF60; USP22; TCERG1; FOSL1; RBM14; TBP; XBP1; MLX; NUP62; COPS2; ZBTB24; CRK; TRIM32; ATF1; PMF1; ZMYM2; GABPB1; PLAGL2; CENPF; HSF2; FHL2; RBBP4; ZFP64; TRIM28; BRPF1; HMGA2; CCDC59; ZBTB7A; VEZF1; ADNP; APEX1; EZH2; PATZ1; SNW1; ADRB2; ZBTB11; ZNF672; FOXO3; KDM2A; MED23; ABL1; ZBTB1; MNT; SMARCC1; CTR9; CDK7; MED6; TAF4; HOXC6; TTF1; NELFB; MAGED1; KAT5; ING2; SNIP1; MED17; ZNF384; NCOA4; SMARCA4; SMARCA5; SMARCE1; USF2; SREBF1; ARID4A; RNF6; BIRC2; PHF20; CEBPB; TBL1XR1; HOXA10; TSC22D2; SIX2; CHAF1B; TSC22D3; ELF2; ZBED4; BAZ1A; USP21; HDAC2; BRD8; IKBKAP; KDM5D; DDX54; HMGXB4; ZNF410; E2F6; IRX4; ELK1; CENPB; RAN; C1D; ATF7IP; PPRC1; RNF4; CBX3; ZNF473; RNF111; SMARCD2; FOXJ3; ZNF443; AATF; HOXB7; PURA; NFKB1; NPM1; PBRM1; NRBF2; RBBP5; HOXD10; PHF8; TCFL5; SMAD5; NFYA; USP16; SIX1; YWHAB; TBPL1; ASXL1; DR1; YBX3; BAZ1B; ILF2; KLF2; PSPC1; HCFC1; SMARCD1; ZNF576; SCAND1; HDGF; AGO2; MED1; PIAS1; NFE2L1; NONO; NR3C1; CNOT1; REXO4; ZSCAN5A; NFIL3; BRD3; UBE2I; PIAS2; CRY1; SIRT7; ZNF764; KAT7; NCOR2; NCOA6; SP3; MED4; PTTG1; TCF12; SFPQ; MTDH; ELF1; DDX5; WDHD1; CEBPZ; DPF2; DNMT3B; ABT1; GTF2IRD1; TAF1D; TSC22D1; ORC2; SMARCD3; ZNF217; BRCA1; TP53; CHD1; BCLAF1; WIZ; MAX; NKX3-1; VGLL4; KAT6A; POLR2A; ATF4; BASP1; HDAC1; PPARG; KDM5B; SAP30; MED27; DEAF1; ADNP2; ERCC3; RFX7; CBX5; PKNOX1; SAFB2; RNF14; MTF1; CASZ1; KLF5; SOX4; MAFG; ZNF629; TRIM16; MYT1L; BMI1; KMT5A; CARM1; TOB1; HNRNPD; TEAD1; EDF1; UBP1; PHF2; PRPF6; FOXN2; ZNF189; ELK3; HMGB2; TCF20; NPAT; TMF1; TADA2A; LIMD1; TRIP6; HOXD11; LDB1; CHD8; NLK; YAF2; RUVBL2; NR2F2; GTF3A; ZNF263; ZNF669; TOPORS; EED; REST; ZNF324; MAFB; IKZF5; CXXC1; PIR; JARID2; ZMIZ2; SMAD2; NFAT5; SMARCA2; GABPA; MEF2A; ZBTB25; CDYL; ZBTB18; BCL10; PMS1; MNAT1; UBTF; ZNF337; SETD2; WWC1; TFAM; TRIM29; SUZ12; CRYM; NFX1; ING1; AIP; EP400; BTAF1; RBBP7; HMG20A; ENO1; SMAD3; CHD4; CARHSP1; MKL2; ZNF124; TBL1X; SSRP1; RCOR1; ETS2; ZNF266; ZNF84; ZZZ3; NCOR1; YBX1; BATF; TULP4; PA2G4; SERTAD2; PRKDC; ANKRD1; RUNX3; CDK8; RNF138; MED24; FOXO4; CCNE1; BANP; DNAJC1; ZNF267; CREB3L1; IRX5; DNAJC2; SIAH2; POU2F1; BCL11B; TAF10; KMT2A; TRRAP; RBPMS; BLM; RREB1; PQBP1; KLF10; KAT6B; PIAS3; ZNF512B; NAB1; SMAD7; RFX5; BCL6; ZNF12; IL16; AFF1; ARNTL; AHR; PCGF2; HMGB3; ZBTB16; NRIP1; ERBB2; CTBP2; ZNF226; RUNX1; HES1; SIM2; ZNF131; RBM39; HOXC10; CHD9; NFIB; MGA; ARID4B; SUV39H1; HOXA5; ECD; RNF141; HLTF; KLF4; MTF2; SNAI2; RBL2; PREB; EYA1; ERG; PITX1; SPEN; RXRA; FOXD1; RBPJ; FOSL2; FOXG1; TLE1; CITED2