Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75091	Torin-2	GSE92742	MCF10A	Human	24h	2uM	EID0432

Response Information :

Types	Number	Response transcription factors
Up-regulation	98	TSC22D3; ABL1; RB1; ATF4; DDIT3; MLXIP; FOXO4; DMTF1; UBE2B; TXNIP; MNT; RELB; CALCOCO1; EGR1; EZH1; INSR; JUP; ZNF177; KLF10; NCOA3; JUND; HMBOX1; TSC22D4; ARNTL; TGFB1I1; ZNF358; ZNF217; NEUROD1; CRK; ZNF117; HDAC6; KLF7; KDM5B; NFE2L1; HBP1; RING1; ZNF415; DBP; MAFG; PNRC1; ZBTB7A; CEBPG; ERBB2; IRF9; CREG1; TGIF1; KLF4; KLF5; TWIST1; EP300; CAMTA2; HTATIP2; CBFA2T2; PCGF3; MAFF; TRPS1; JUNB; TBX21; HMGA1; HOXA1; BCL10; RBL2; FOXD1; SMAD3; RBM39; BASP1; SERTAD2; FOSB; MZF1; TAF10; HDAC9; MSX1; EGR3; ZNF160; KLF6; BRD2; BTG1; TFDP2; MXI1; TOB1; CITED2; PHF1; BRD4; KLF9; STAT6; MTA1; ZIC1; ST18; ZNF91; RUNX1; PDLIM1; KLF13; ZNF589; IRF7; IKZF1; ZEB2; CREB1; NR4A2
Down-regulation	109	MYCBP; MYBL2; GMNN; TFDP1; ZBTB24; CCNA2; RUVBL1; PARP1; TGS1; PPRC1; WDR77; ABT1; EZH2; ZNF551; TEAD4; ADRB2; DNMT1; IKBKAP; REXO4; FOXM1; CCNH; TTF1; CENPF; WDHD1; SP3; TAF1A; NANOG; NPM1; ZNF512B; IFI16; ETV5; NR2F2; CCDC59; MEIS2; PSIP1; SUB1; TFAM; CBFB; RAN; ZNF195; C1QBP; RNF138; ETV1; ZNF180; REL; CITED1; ADNP; ZNF136; ITGB3BP; PSMC3IP; NRIP1; GTF2I; LIN28A; MTDH; TCEA2; MED6; HSF2; PMS1; GTF2A2; ZNF267; NFE2L3; ZNF107; TFAP2C; HMGB2; MTF2; ISL1; BNC2; RFX5; BRCA1; PITX1; ZNF652; BAZ1A; ZNF274; TCF21; HES1; PITX2; ZNF544; THAP10; PAXBP1; CDK2; ZNF22; CEBPZ; ZBTB18; BCLAF1; E2F8; HLF; ZEB1; ECD; HIRA; CALR; MYBL1; PBX3; RBBP8; JUN; HOXB6; PCGF2; TRIM22; TLE4; SOX11; PBX1; NR1H2; PEG3; NR2F1; ID3; WT1; TBX3; POU2AF1; LEF1; SUV39H1