Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75024	Mk-2206	GSE92742	MCF10A	Human	24h	10uM	EID0432

Response Information :

Types	Number	Response transcription factors
Up-regulation	148	PPARD; CEBPA; CREM; ABL1; DAXX; SMARCD2; TEAD3; CBFA2T3; KDM5A; ETV5; JUP; REL; CALCOCO1; PBXIP1; SP3; ZNF117; AES; KAT2B; FOXE1; MNDA; IRF6; NFIL3; HMGA2; PLAGL1; TGFB1I1; TCF25; TSC22D3; CRYM; RXRB; ELF3; IRF9; BACH1; DLX4; SOX9; ZNF423; ZNF160; NAB2; SND1; ZNF264; ZNF611; KLF3; HBP1; PRMT2; FHL2; ZNF710; PRDM1; CIZ1; TLE2; TGIF1; SP100; IRF8; TRIM32; FOXF1; TRPS1; BNC2; MAML1; MAF; URI1; KDM5D; CHD9; NEUROD1; HHEX; MYBL1; ZNF331; CTCF; AHR; CUX1; SERTAD2; RING1; SIAH2; TCF7; BCL11A; IRF1; ZNF665; SMARCD3; ZZZ3; TRIM22; CTNNB1; HIC2; CD3D; CBX7; PHIP; PCGF3; SALL1; BCL6; TBX3; SPDEF; JAK2; HLF; MYCL; ZSCAN18; TCEA2; ERBB4; ZBTB38; LYL1; SP140L; BASP1; CREG1; STAT2; TDP2; CHD1; ID4; FOXF2; ZNF12; NFKB2; OSR2; BHLHE40; MED13; RNF10; RCOR1; TBL1X; TFEC; NR4A3; WNT4; RREB1; NR2F1; KLF2; ZFPM2; SATB1; TRIM29; ELF1; PHF1; TP63; NR4A1; ARID1A; RERE; MEIS2; IRF7; MYB; HOXA5; KLF4; NFE2L2; TRIM16; ZSCAN31; HLX; PBX1; ZNF721; POU2AF1; CREB3L2; TCF4; SMARCA1; TXNIP; IFI16; CREB1; NR4A2; ESR1; LEF1; ARID5B
Down-regulation	193	FOS; CCNA2; TAF4; BRIP1; NUP62; RUVBL1; ZNF384; ATF1; PPARG; VGLL4; TFDP1; PATZ1; ZNF10; ZNF195; TBP; FOSL1; MYCBP; PHF8; PMF1; ZNF668; BRD8; LMCD1; PMS1; TAF1A; ZNF473; CTR9; XRCC6; TFAP2B; GABPB1; EGR4; ZNF227; WDR77; MYBL2; RFX7; PPRC1; PRKDC; PIAS2; TCERG1; MLX; MEOX1; NCOR2; EZH2; HOXC6; VEZF1; HSF2; PEX2; ZNF23; CRY1; HEY1; PSMC3IP; PA2G4; ELK1; ZNF281; DDX5; INSM1; TTF1; TCEA1; TEAD1; SMARCB1; ERCC2; CAPN15; SMAD1; TGS1; MTA2; MLLT10; KAT2A; CENPF; HMBOX1; MYF6; BRF2; CREBZF; ADRB2; ATF4; CNBP; ZBED4; FOXN2; CBX3; HEY2; ZNF32; NFE2L1; NFIB; MSX1; THAP1; ZNF211; ZBTB1; TGIF2; ZKSCAN7; HAND1; ZBTB32; THAP11; ID3; MAFG; MTDH; ZSCAN12; TADA2A; TAF10; GTF3A; ZBTB25; BIRC2; CHD7; RUVBL2; TMF1; EED; CCNC; YBX1; TOB1; ASCL1; MECOM; DLX2; CSDE1; PGR; POLR3F; BMI1; PTTG1; ADNP; TFCP2L1; TFAM; AIP; TOX; DNMT3B; BLM; SALL2; ENO1; MYNN; ZNF143; NR1I2; YAP1; ATF5; LITAF; CNOT3; HOXB6; HOXB7; ZBTB18; ZMYND11; POU3F2; FUBP1; ORC2; E2F3; VPS72; LOXL2; PAXBP1; ATF2; RAN; MAZ; SOHLH2; MED1; FOSB; ZNF3; DDIT3; PURA; TBPL1; SMARCA5; SAP30; SMARCE1; ZNF302; YBX3; MDM4; ELF5; PBX3; KAT6B; CEBPD; C1QBP; ATF3; FOXG1; ZNF165; TSC22D2; EMX2; PDLIM1; HIPK3; FOXO1; ERG; KLF13; MTA1; TAF9B; CEBPZ; SMAD3; GATAD2A; ZBTB16; HOXB5; SOX17; ISL1; TWIST1; KLF5; KLF9; MTF2; PSIP1; CALR; SPEN; EYA2; ID1; TOX3; SUV39H1; IKZF1