Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74936	Tivozanib	GSE92742	MCF10A	Human	24h	10uM	EID0432

Response Information :

Types	Number	Response transcription factors
Up-regulation	51	EGR1; XBP1; NFATC3; EGR4; PPARD; KDM2A; KLF10; EGR2; HOXC10; MEOX1; EGR3; JARID2; HOXA1; E2F3; POLR2A; SMAD3; SMAD5; DDIT3; CBX6; POU2F2; MNAT1; CARM1; FOXC1; TRPS1; MAFF; TSC22D4; MECOM; MAFB; FLNA; KLF4; KLF9; PPARGC1A; ZEB2; RNF141; NKX2-2; SOX9; BHLHE40; ZIC1; HOXC6; STAT6; NAB1; HLTF; TOB1; BMI1; TWIST1; TGFB1; TXNIP; JUNB; DLX2; SCAND1; ZNF589
Down-regulation	80	PUF60; ZNF7; ZNF551; TFAP2C; ZNF44; FOXI1; BACH2; ZNF180; ZNF264; REL; ZNF623; MEIS2; WT1; DNMT1; AR; ZNF586; IKBKAP; APEX1; RAD21; STAT4; ZNF136; INSM1; FOXE1; ZFP36L2; PBX3; ZNF43; TRIM24; ZNF268; TEAD4; FOXN3; MYCL; ZNF652; LITAF; BNC2; ZNF611; ZNF107; TCF21; WNT4; ZBTB20; ARNT2; ASCL1; YBX3; TCF7; ZNF721; NKX2-1; TBX3; ZNF274; ZNF91; NFE2L3; HHEX; ZHX2; SOX11; ZEB1; ZNF160; IFI16; SOX13; HOXB6; ZNF544; GRHL2; SOX17; TLE1; ELF3; ZFHX3; PLAGL1; BCL11A; HOXB5; PIR; HOXB2; MYBL1; OSR2; ZFPM2; LEF1; MNDA; JUN; TLE4; TOX3; PEG3; NFE2L2; ARID5B; IKZF1