Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74906	Cgp-60474	GSE92742	MCF10A	Human	24h	0.4uM	EID0431

Response Information :

Types	Number	Response transcription factors
Up-regulation	223	FOXO4; L3MBTL1; SOX2; ID4; ESR1; PBX1; SPDEF; ZNF345; NHLH2; OLIG2; SOX17; ZNF623; CSDC2; ZNF136; PNRC1; MED14; CDIP1; ZNF667; SIX6; ATF3; ST18; SPI1; ZFPM2; WWP1; WT1; PRDM14; BNC2; RING1; HNF4G; SMARCA1; HOXD3; TSHZ2; MAFF; SHOX2; HOXB1; BARX1; PPARD; ZNF586; RBPJL; HSF4; HIPK2; HEY1; HIC1; FEZF2; SND1; ZIC3; HIF3A; TRPS1; ZNF606; ERBB4; PLAGL1; IRF6; ZNF257; CRX; SALL2; ZNF816; ZNF195; ZNF334; ZNF264; NANOG; KAT2A; ZNF350; ZNF362; SOX3; HSF1; NAB2; ZNF304; TFAP2A; VENTX; ZNF223; AR; ZBED2; HDAC9; ZNF423; MYT1; ZNF562; SIN3B; ZNF835; GMEB2; GBX1; ZNF682; THRA; ZFX; HMX1; PEG3; NR4A3; CEBPE; HOXB5; ZNF415; HBP1; EGR2; ESRRG; RORC; ZNF787; ZNF426; NR1H2; IRF9; ERF; EP300; GLI3; HAND2; ELF4; ZNF44; ZNF654; EYA2; TCEA2; RLF; SSX1; MYCL; ZNF135; MYCN; ZNF419; IRF5; ARID5B; HDAC5; SIRT2; SUPT3H; HOXD13; TWIST1; TCF7L1; ZNF93; INSM1; HOXD1; MITF; ATF2; CNOT3; PBX2; PRDM2; EMX2; MED12; ZNF492; HOXB13; FOXG1; ZNF529; MYNN; TSC22D3; TCF7L2; ZSCAN9; ZNF432; LOXL2; LIN28A; BRD4; KLF7; ZNF141; CAMTA2; MAFB; ZNF536; RARG; ZNF91; MDM2; ZNF580; DLX4; PKNOX2; ING4; CUX2; TERF1; ZNF587; HIRA; ZNF331; NR0B2; HLX; RBFOX2; BHLHE41; SP140L; SRF; VGLL1; ZNF117; MEIS2; IRF8; ZNF551; MXI1; RYBP; TGFB1; E2F2; OSR2; ARHGAP35; TOX3; ETS1; SCAI; MEOX1; ZNF711; NR2F1; ID3; BHLHE40; ZNF83; BACH2; ASCL1; PHF1; NR5A2; FOXO1; NR4A1; CALR; NEUROD1; NFATC4; ZNF573; PBX3; ZSCAN18; BIRC2; NKX2-2; MAF; CDK2; INSR; POU4F1; IRF7; TGFB1I1; DLX5; CITED1; PRRX1; KLF13; MYRF; FOXI1; JUN; KAT2B; IRF1; ZNF512B; POU2AF1; ZNF274; TBX3; CREB3L2; TFEC; ZIC1; DACH1; ARNT2
Down-regulation	352	FOXO3; PSMD9; RBBP4; ZMYM2; ATF1; ADRB2; TBL1XR1; TBL1X; RBM14; MYC; ATF5; BCLAF1; HOXB7; RNF14; SFPQ; PMS1; SIX2; BRD3; PUF60; NR2F6; CEBPZ; ORC2; HOXA5; BAZ1B; TCF20; ZNF672; UBP1; TBP; ERBB2; DDX54; GTF2IRD1; SUV39H1; PPARG; SAP30; MED6; NCOA6; TLE1; TRIM32; VGLL4; CBX3; SP3; SUZ12; ZNF282; POLR2A; BLM; HDAC2; PSPC1; SMARCE1; CARHSP1; PURA; ZBTB16; SNW1; ERCC3; WDHD1; CHAF1B; ING2; TCFL5; ZBTB24; MNAT1; YAF2; NRF1; ADNP; NFYB; PSMC3IP; CHD1; HOXA11; SAFB2; SMARCA5; CDK8; NR2F2; NFRKB; HNRNPD; ARID4A; TRIM16; PAWR; PBRM1; ZBTB1; CCNH; NLK; ZNF131; RUNX1; KDM2A; CDK7; LIMD1; KAT6A; ARID4B; CBX6; RNF6; ZFP64; NFX1; DPF2; MED1; NPAT; GCFC2; REXO4; HOXA10; ZBTB7A; PATZ1; PHIP; CREBZF; PMF1; TULP4; GTF3A; KMT5A; PCGF2; NELFB; MGA; CENPB; BRIP1; BMI1; AATF; JARID2; PHF20; EED; NFYA; CEBPD; CNOT1; TTF1; BRD8; KAT7; ZZZ3; TRIP6; BRCA2; MLX; CRK; NRIP1; NR2C1; SAP130; NCOR1; ZNF473; CLOCK; VEZF1; SMARCA2; ZNF446; HSF2; TRIM27; THAP11; ASH2L; ABL1; HOXC6; SREBF1; KDM5A; TMF1; ZNF384; TRIP4; FOXC1; KAT5; BATF3; ETV6; CCNC; DDX5; IRF2; CBX5; ELF1; UBE3A; ANKRD1; SIAH2; RREB1; BRCA1; DNAJC1; REST; ATF6; MAGED1; TLE4; SIM2; RBBP7; WHSC1; STAT6; TAF5; SFMBT1; ETV1; RAN; BRPF1; ELK1; SMARCD3; TEAD4; MLXIP; ZNF593; NFKBIB; CHD9; ARNTL2; RFX7; TADA2A; ZSCAN5A; KMT2A; HOXA7; HMGN3; UBE2B; CASZ1; ZNF337; POLR3C; ELF2; ERG; HCFC1; RBL2; MED13; TRRAP; BAZ1A; CTBP2; SMARCA4; PIAS3; ZBED4; SMARCD1; NAB1; CREB3L1; EDF1; HOXC10; RBL1; BAZ2B; NCOR2; POU2F1; TFCP2; PITX1; FLI1; IRX5; HMG20A; TRIM29; BLZF1; URI1; CHD3; HLTF; AGO2; HMGB1; ZNF32; PIAS2; NCOA4; ZMYND11; CENPF; CTBP1; RBPMS; TOB1; SMAD2; PQBP1; CTR9; NKX3-1; ZBTB14; ZBTB25; GABPB1; ZSCAN32; TFDP2; ZNF189; HOXA1; CEBPA; RUVBL2; RNF111; KLF2; CITED2; THAP7; TSC22D1; RFX5; BATF; XRCC6; PRKDC; IKBKAP; TP53; ZBTB18; ZNF84; APEX1; MEF2A; ZNF23; CCNA2; KLF12; KLF4; ISL1; RBBP5; ZNF217; ZNF629; PHF2; FOXJ2; AFF1; STAT4; ELF3; SIRT7; ZNF146; PIR; ZMYND8; UBE2I; ZHX2; ZNF443; MAZ; NFAT5; NPAS2; YWHAB; ZNF266; TGIF1; CEBPG; ADNP2; ZNF200; HMGB3; NPM1; ETS2; ATF7IP; TSC22D2; ZMIZ2; ELK3; ZBTB38; TRIM28; PRRX2; DNMT3B; LYL1; HOXC4; EZH2; ETV4; ZNF652; NR1H4; CUX1; TCEA1; HDAC1; TAF9; HDGF; TADA3; SMARCC1; SMAD4; HTATIP2; SOX4; STAT3; PSIP1; VDR; ZNF281; RNF141; FOXD1; ATF4; TP63; DEK; YBX3; ING3; NFIB; REPIN1; KDM5D; ZNF430; REL; TAF9B; LPIN2; MED23; GATAD2A; FOXM1; KLF5; SMARCD2; ZFHX3; NFIL3; HES1; ECD; AHR; TXNIP; SMAD3; IFI16; MTA1; TBPL1; CBFB; KDM5B; BCL11B; LEF1