Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74880	Torin-2	GSE92742	MCF10A	Human	24h	10uM	EID0431

Response Information :

Types	Number	Response transcription factors
Up-regulation	143	HINFP; TSC22D3; STAT5B; ABL1; HDAC6; JUND; DMTF1; PPP1R13L; PAWR; HMG20B; HBP1; FOXO3; DDIT3; KLF6; HSF1; CIZ1; ZNF768; BRD2; MED16; HTATIP2; ZNF195; CALCOCO1; HDAC5; EZH1; CDK9; TGFB1I1; PBXIP1; TCF7L1; SRCAP; MAFG; SOX13; KLF3; FOXO4; LZTR1; PSPC1; ZHX2; IRF7; PRMT2; AES; ZZZ3; SMARCC2; ELF4; KLF11; ZNF688; RELB; RING1; NFE2L1; ZNF211; PHIP; NELFB; ATF4; JUP; PHF1; BRWD1; CREG1; ZMIZ2; PIAS1; TXNIP; RBPJ; INSR; RNF10; CREB3; MYRF; RELA; ST18; SIN3B; ZIC3; NR2C1; EHMT2; TCF7; ERBB4; CBFA2T3; CIR1; KLF4; CEBPG; ZNF444; ARID5B; ZBTB16; CEBPD; WWP1; CAMTA1; SIRT7; IRF9; TFEB; EDF1; TRIM16; OSR2; KLF13; STAT5A; ZNF83; CARHSP1; TDP2; LIN28A; CITED2; KLF7; TRIB3; TCEA2; BAZ2B; ZSCAN18; TADA3; CBX7; ARID1A; CNOT3; FLNA; ZNF217; NCOA2; TCEA1; TCF25; ZNF117; BTG1; ZNF91; BRD4; ZNF423; SSBP3; ZNF329; FOXN3; ZFP36L2; SP100; CNOT2; ASCL1; PAX5; AEBP1; HMGA1; GATA6; TGIF1; ELF3; IRF8; ATF3; NCOA3; INSM1; FOXO1; POU2AF1; ELF5; SOX4; HIVEP1; NKX2-1; KLF2; RBPMS; ZFPM2; PBX3; ARNT2; KLF5; KDM5B
Down-regulation	149	HMGA2; ADRB2; C1QBP; RBBP7; RBBP4; TFDP1; FOSL1; PARP1; C1D; FHL2; RUVBL1; PTTG1; ATF1; MED6; MYCBP; TFAP2A; TFAM; SUB1; SUV39H1; ITGB3BP; CEBPZ; NR2F2; HDAC2; SMAD5; RUVBL2; WDR77; SFPQ; TBP; BCLAF1; WDHD1; RBL1; ENO1; PBRM1; TBL1XR1; CHAF1B; ZBTB18; HOXB7; HOXB9; HLTF; EGR2; HOXA5; NFKBIB; MTF2; CBFB; MED1; MED24; TGS1; HNRNPD; ORC2; MNAT1; SIX1; ZNF302; CCNA2; MED7; ATF5; THAP10; GCFC2; MECOM; MYBL2; PLAGL2; BLM; SMARCD3; RUNX1; PMS1; EED; UBE2L3; BMI1; PSMC3IP; WT1; ZNF22; E2F3; PIAS2; NAB1; TAF9B; UBP1; EGR3; ETV1; RBBP8; MYT1L; SOHLH2; PITX1; MAX; SMARCE1; TRIM32; USP16; HHEX; HOXA7; WWTR1; RAN; NR1H4; ERG; TAF4; CBX3; CENPF; BATF3; WWC1; SAP30; NUP62; LOXL2; TGIF2; ZBED2; JARID2; HOXA1; ELK3; ZBTB24; NFAT5; ASH2L; NLK; TAF9; ZNF239; HMGB3; SMAD1; RNF138; BRCA1; COPS5; FOXC1; ZNF200; ECD; ZNF267; TEAD1; MAGED1; IFI16; PITX2; PAX8; BAZ1A; RFX5; ESR1; ZMYND8; HOXB6; ETS1; LEF1; GABPB1; EZH2; MYCN; HOXB2; VDR; HDAC1; HOXA10; IRF4; IRX5; HES1; PURA; STAT3; SMARCA4; NR2F1; HOXC10; HOXC6; GTF2A2; TWIST1