Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74846	Plx-4720	GSE92742	MCF10A	Human	24h	0.4uM	EID0431

Response Information :

Types	Number	Response transcription factors
Up-regulation	318	SOX2; GLI2; BRWD1; TBP; MED14; PPARD; TGFB1I1; PAX8; FOXO4; ETV1; SOX13; FOXE1; EGR1; RNF138; ZNF500; ERF; FOXF1; CBFA2T3; DEAF1; TGIF1; BRD2; HINFP; UBE3A; ELF4; SPI1; NANOG; ZNF195; ST18; LOXL2; CIITA; CENPB; MBD2; BARX1; WWP1; OLIG2; SATB2; ZBTB3; TCF21; HMGXB4; LHX2; PIAS2; NFKB2; SMAD2; IRF6; ZNF304; TGS1; SAP18; ZNF484; CREB3L1; ZNF623; HDAC4; TRAF6; ZNF189; CARF; UBE2L3; BRIP1; AES; JUP; ZKSCAN4; ZNF124; PRDM10; PROX1; CREM; HOXA2; EBF2; SMAD7; PBX1; THAP9; TAF4B; ZNF552; ZNF286A; SUPT3H; ZNF83; ZNF835; IRF1; NFYC; POU6F2; CDK8; PLAGL2; ZNF711; SAFB2; ZNF506; ZNF419; LIN28A; BNC1; ZNF580; ZNF155; NHLH2; ZXDC; LZTS1; ZNF202; HOXA4; MED15; ZNF75D; SUPT6H; POU4F1; SOX12; PNRC1; ZNF362; ZNF551; FOXD1; YEATS4; KDM4C; RLF; LZTR1; ZNF211; RNF2; ZNF574; EP300; TEF; ZNF175; KLF11; MEN1; NCOA6; ZNF135; TONSL; CAMTA1; NR2F1; ZNF12; ZFP2; TRIM22; ZNF112; CDX1; ZFY; TLE2; HSF4; NR3C2; ZNF250; KMT2A; TGFB1; STAT2; IRF7; ZNF444; ZNF292; ZNF134; ZNF217; ZNF267; PML; ING3; MLXIP; FHL2; E2F8; UBP1; ZNF74; ZNF423; SIX6; ID4; KLF3; FOXG1; ZNF350; HOXD13; EP400; ZNF184; SETDB1; BPTF; ZNF287; NEUROD1; ZBTB1; ZNF778; MBD1; ZNF764; MKL2; HLF; ZNF473; TEAD3; MECP2; TDRD3; YBX2; SCAI; ZIC3; GFI1; TEAD4; PRDM13; CBFA2T2; PPARGC1A; TLE4; GTF2F1; GRHL2; TAF10; TCF7; BNC2; FOXN3; FOSL2; ZBTB6; ETV4; BCL6; HMGA1; RERE; ARHGAP35; ZNF248; ZNF493; CAPN15; PSMC3; CHD1; ZNF557; ZBTB43; BCOR; EHMT2; ZNF24; NCOA2; KMT2B; ZNF646; HEY1; RCOR3; SOX11; ZBTB20; EGR2; CBX7; ZNF223; CDK2; ZNF227; FOXI1; ARNTL2; ZNF467; REL; HR; SSBP2; RRN3; OSR2; MEF2D; MAF; TERF1; ZNF45; UBTF; MEOX2; BCL3; ZFPM2; ARID5B; ZNF16; TSG101; CALCOCO1; MDM2; SUPT4H1; NKX2-1; ZNF215; GLI1; HIVEP1; RNF141; SMARCD2; HMGB2; MAML1; TAF11; SMAD4; MNDA; MAFB; HOXB13; HIRA; SNAI1; CREG1; CDX2; NPAT; RB1; CNOT3; KLF4; MED12; TOPORS; ZNF329; TP63; ZNF281; INSR; PATZ1; THAP7; NR1D2; BCL11A; KLF10; LITAF; TRIB3; SOX5; ZNF410; VDR; FLNA; SRF; MAZ; NR1I2; BACH1; AGO2; TERF2; ELF1; TDP2; RARA; MECOM; NKX2-2; CNOT2; PAXBP1; RREB1; DLX2; ZNF587; KLF7; HDAC7; PEG3; ZNF468; GTF3A; IRF9; ZNF573; BCL11B; SOX10; ZNF274; FOXM1; EED; TFAP2C; IKBKAP; AEBP1; MYCL; EMX2; ZBED2; PHF2; SNAI2; POU2AF1; MYBL1; TXNIP; TBX3; NFE2L2; JUN; ZNF331; RBPMS; KDM5B; TWIST1; SMAD3
Down-regulation	286	MYC; PARP1; CRK; CDK7; RUVBL1; HDAC2; PCBD1; ATF1; MYCBP; SIX2; ENO1; TFDP1; HMGN3; SND1; RBBP4; TRIP6; ATF6; RHOA; WDR77; DR1; ZNF593; TCERG1; NFKBIA; ADRB2; C1QBP; URI1; MED6; ZNF302; BATF3; RAN; NR2F6; TRRAP; RBBP7; ILF2; FOXC1; CCNH; KLF6; E2F5; PRDM12; ZNF426; HOXB6; RNF4; PFDN5; NACA; USP22; WHSC1; ZKSCAN1; CERS4; BRD8; RFC1; CDYL; HOXD1; MITF; ELK1; AATF; BTG1; CTBP2; REXO4; VEZF1; MXD3; SP3; MSX1; NPM1; NR2F2; TCEB2; ZBTB24; CLOCK; KAT2A; MED17; CNOT1; SMARCA5; SIRT2; KMT2D; HOXB9; CCNC; TAF12; MXD4; TRAK1; CBX5; ABT1; YBX1; WWC1; MNT; RFXANK; BRD4; DNMT1; SUB1; ZNF562; RUVBL2; CBX3; GTF2IRD1; STAT4; ZNF32; EDF1; TBL1X; MED24; NFKBIB; MYOD1; SMAD5; ATF2; ESR1; ZBTB18; HSBP1; IL16; PGR; MYBBP1A; SIX3; SMARCD1; TCEA1; PPARG; ACTL6B; MED1; BLZF1; BANP; MED13; TOX4; C1D; PRKDC; ZBTB38; ING2; ZBTB16; PCGF3; TCFL5; PREB; ZNF146; DNAJC1; HOXB2; SERTAD2; RYBP; BTF3; RNF6; PEX2; ANKRD1; CRY1; THAP4; ZNF239; PMF1; HTATIP2; TOB1; UBE2I; SIN3B; ZNF576; HDAC5; PRRX2; ZZZ3; YAF2; SIM2; PHF8; TRIM27; TCEA2; MED4; PHOX2A; COPS5; ARL2BP; CDC5L; ZNF282; HOXA11; POU2F2; APEX1; SUPT5H; RBBP8; SSRP1; BAZ1B; HMBOX1; CRYM; ZNF43; HOXB1; RBL2; NR3C1; PURA; MAGED1; MED7; NONO; SALL2; NFIC; E2F6; POLR2A; BARX2; HDAC9; HLX; TSC22D1; TEAD1; TOX; PIR; BRD7; CBFB; TOX3; TLE1; BASP1; HNRNPD; NCOA4; HLTF; JUND; TAF9; GATA2; CHD9; ZNF721; BBX; TMF1; MXI1; TRIM16; SIRT7; PA2G4; NRBF2; REPIN1; ATF4; HDAC3; ASH2L; ZNF140; SMARCE1; GATAD2A; ZNF430; BAZ2B; ID1; ZNF44; MEF2A; MYRF; KLF2; NRIP1; PAX5; PITX2; CNBP; CITED2; ZBTB11; CEBPB; HBP1; KLF13; CCNA2; IRF2; SIAH2; XRCC6; IRF4; TRIP4; MBD4; NAB1; ZNF160; CTBP1; ZIC1; AR; PSIP1; PITX1; DDIT3; ZNF415; PDLIM1; ASCL1; FOXA1; CITED1; NUP62; DEK; ZNF652; FOXL2; CTNNB1; ZEB1; DDX5; PLAGL1; ZMYND8; PHOX2B; ZFHX4; FOXF2; PAX6; SMARCA4; ELF3; ELF5; BRPF1; ZFP36L1; TRIM29; GTF2A2; YBX3; NFATC1; PBX3; ATF3; RFX5; ARNT2; CREB3L2; INSM1; STAT3; EYA1; VPS72; SSX1; IRX5; RUNX3; MTA1; EGR3; TBPL1; HOXC6; ZNF91