Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74813	Mk-2206	GSE92742	MCF10A	Human	24h	2uM	EID0431

Response Information :

Types	Number	Response transcription factors
Up-regulation	324	NR3C1; FOXO4; GLI2; SSBP2; HDAC6; TBP; YEATS4; HINFP; EGR1; STAT5B; EGR2; PAX8; BRWD1; KDM5A; ZNF711; ETV5; IRF8; BCL6; SPI1; DAXX; ABL1; WWP1; BARX1; ZNF506; ZNF83; NFE2; SUPT4H1; CALCOCO1; RXRG; TEF; HSF4; BPTF; CRTC1; L3MBTL1; ZKSCAN7; ZNF665; ZNF764; SIX1; ZNF419; BNC2; STAT5A; ZNF135; KMT2A; MED14; RBFOX2; PAWR; SIX6; ZNF134; ZNF362; ZNF778; HIC1; UBE3A; IRF7; PDX1; FOXB1; CAMTA1; IRF3; MBD2; ZSCAN16; SUPT3H; ZNF329; ATF3; ARHGAP35; ZFPM2; ZNF672; CIITA; MAP3K10; LHX1; ZNF267; ARID3A; ZNF701; PIAS1; VGLL1; CREB3L1; PBX1; JAK2; UBP1; HNF1A; TEAD3; ZNF606; PEG3; ZNF468; RBPJ; SP110; ZXDC; TGIF1; ETV6; SOX10; ZNF177; MYOG; CNOT6; CDK8; LOXL2; KAT8; FOSL2; ZNF165; TCF21; EMX1; AFF3; MYRF; ST18; RNF138; ZNF562; GLI3; STAT2; NCOA2; NFATC4; BACH1; ELF4; NFKB2; KLF3; SP1; ERBB4; ZNF287; SP140; ZKSCAN3; ZNF623; NR4A1; BCL11A; TLX3; SOX13; REXO4; ZNF835; AHR; OSR2; LITAF; TRIM33; SIM1; CBFA2T2; MDM2; LYL1; PSMC3IP; ZNF334; SERTAD2; MYT1L; ZNF174; FOXN3; SRY; GFI1; CBL; GON4L; TBX19; PBXIP1; PRMT2; ZNF473; SMAD2; MEOX2; ZNF813; SP100; RLF; MBD1; AEBP1; MED7; PPARA; EBF2; FUBP1; FOXE1; ZNF304; NR3C2; ZNF467; KAT2A; DDIT3; ZNF384; NKX3-1; GATA1; SP140L; HMGB2; APBB1; CREBZF; ACTL6B; NR1H4; SIX3; CEBPZ; CREM; ZNF136; BNC1; TAF11; FOXI1; AFF2; ZNF264; CSDC2; WWC1; NR1H3; AGO2; AES; SMARCD2; PLAG1; E2F3; ZNF248; IFNB1; TULP3; NEUROD1; LZTR1; KLF7; ZNF611; ZBTB25; CIZ1; HMX1; SOX11; IRF9; MEIS1; ZNF44; KDM4C; LDB1; ZNF529; REL; ZNF184; ZNF423; ZNF224; CRYM; TAF10; ZNF692; TULP4; ZNF146; RORC; NR4A2; PHF1; ZNF331; RARG; ZNF33B; KAT7; BACH2; MECOM; TGFB1I1; ZNF292; MYB; DNMT1; CXXC1; ZSCAN18; SETD3; KLF6; NR0B2; EHMT2; GMNN; TLE2; KLF1; TBX21; ZNF263; CREG1; ZNF721; FOXF1; ARID5B; HDAC3; SND1; CREB3; SMAD7; TRIB3; ZNF415; PROX1; ZBTB20; SMARCD3; UBE2L3; ZNF160; FLNA; ZBTB1; EYA1; SOX5; IRF1; PHIP; SFMBT1; BASP1; ING4; POU2AF1; EHF; CHD7; TBL1X; WNT4; ZNF189; ZNF571; RSF1; ZNF45; KAT2B; ZNF274; ZSCAN31; CBFA2T3; TRIM22; TCF7L1; PAX5; ZNF580; HHEX; ZNF215; TCF4; NRIP1; NUP62; HDAC9; CEBPA; BCL10; HIPK1; BBX; NCOA1; LPIN2; TCF7L2; MNDA; ID4; JUN; HIVEP1; HOXB2; MYCN; KLF10; HLF; KDM5D; EED; TCEA2; MAF; CITED2; PAXBP1; GRHL2; ZNF573; WT1; ATF7IP; ZFHX3; EGR3; ARNT2; PBX3; NKX2-2; KLF4; ZNF652; BMI1; HIC2; EMX2; TBX3; NFE2L2; TFAP2C; MAFB
Down-regulation	300	MYC; DRAP1; RBBP4; PARP1; CDK7; PSMD9; ZNF593; PUF60; MDFI; HMGB1; NFKBIA; SUB1; ADRB2; ZBTB16; DPF2; FOSL1; MED16; RBBP7; SMARCE1; FHL2; TCEB2; ARL2BP; PCGF2; NACA; TFAM; EDF1; SIM2; DDX54; CCNH; PPARG; RBL2; THAP4; PIR; MSX1; PRKDC; MED4; PMF1; HMGN3; ORC2; PFDN5; ZNF302; PPP1R13L; PIAS3; MED6; TGFB1; CTR9; CBX3; ILF2; COPS5; ATF1; CEBPB; SP3; NFKBIB; RFC1; BTF3; CCNC; TFDP2; CNOT1; MED1; BRD8; RAD21; ELK3; NPM1; ESR1; CTNNB1; EWSR1; UBE2I; SMARCA5; ZNF32; WHSC1; ZNF212; ZNF576; RAN; HOXD1; ATF6; ETV1; TAF12; FOXP3; PHF8; SFPQ; TRIM29; TCEA1; ARNTL; ATF5; KMT2D; ADNP; SOHLH2; RELB; SMAD5; MSC; ZBED1; SAFB; SAFB2; HSBP1; HTATIP2; TOB1; STAT4; ZNF589; XRCC6; SUV39H1; SMARCD1; RNF6; MTA2; DNAJC1; PA2G4; GTF2IRD1; THAP11; RFXANK; TLE1; ZNF205; MXD4; GMEB2; E2F5; C1QBP; NELFB; NR2C1; ARID1A; BAZ1A; ID1; HMGB3; NFIB; SMARCB1; ELK1; ZBTB18; ENO1; CCDC59; KAT5; ID2; CRY1; MYBL2; PSIP1; PMS1; IRX4; NFATC3; RORA; TCFL5; TSC22D2; SMARCA4; NFIC; CTCF; ERCC3; ZNF131; REST; ZMYND11; ASH2L; POU5F1B; DNAJC2; CNOT3; ZBTB38; HSF1; SUMO1; RUVBL2; YAF2; MAGED1; BAZ1B; POLR2A; ID3; HNRNPD; ELF2; TRIM32; AATF; SOX9; TRPS1; TEAD1; LMCD1; YWHAB; ZNF22; SSBP3; HDAC1; TSC22D1; TADA2A; E2F6; TBL1XR1; SUZ12; FOXA1; TTF1; TCF3; NFAT5; RBM14; CBX6; HLTF; TOX; TAF9B; HOXB7; BATF3; BANP; ZBTB7A; CALR; TSG101; JUNB; KDM5C; POLR3C; BCLAF1; TP63; CRK; CEBPG; ZMYND8; TMF1; MED15; ZNF282; TRIM28; NR2F6; JUND; HDAC2; SPEN; VEZF1; PTRF; HOXA5; DDX5; NCOR2; CDK2; POU3F2; NFE2L1; CCNA2; ZNF226; MITF; AFF1; FOXD1; NONO; ATF2; IFI16; MXI1; HOXA7; MED21; MEF2C; MYCBP; E2F2; ZNF43; PAX9; SIX2; CBX5; ZBTB17; SOX15; SREBF1; HMBOX1; BRCA1; TEAD4; YAP1; TP53; PSPC1; BTAF1; CARHSP1; GTF3A; PPARD; PCGF3; NLK; RNF4; FOXO1; MNAT1; NFIX; RNF141; CITED1; FOXG1; ZNF91; KLF5; SUPT7L; ZNF410; SMAD1; RBBP8; ZNF432; BCL3; ZBTB24; HEY2; SOX17; MYCL; HEY1; GABPB1; ZNF430; KLF13; CTBP2; PATZ1; HLX; TWIST1; NR2E1; NKX2-1; VPS72; CNBP; ETS2; AR; NAB1; EN1; GATAD2A; FOXM1; TBPL1; PEX2; NR2F2; SMAD4; CUX2; SOX4; SNAI2; MLXIP; NFE2L3; NPAS2; PRRX1; YBX3; IRX5; STAT3; NFIL3; KDM5B; MTA1